研究成果

[雑誌論文] A 590 kb deletion caused by non-allelic homologous recombination between two LINE-1 elements in a patient with mesomelia-synostosis syndrome.

Kohmoto T, Naruto T, Watanabe M, Fujita Y, Ujiro S, Okamoto N, Horikawa H, Masuda K, Imoto I. 2017

[雑誌論文] Genome-first approach diagnosed Cabezas syndrome via novel CUL4B mutation detection.

Okamoto N, Watanabe M, Naruto T, Matsuda K, Kohmoto T, Saito M, Masuda K, Imoto I. 2017

[雑誌論文] Targeted exome sequencing and chromosomal microarray for the molecular diagnosis of nevoid basal cell carcinoma syndrome.

Matsudate Y, Naruto T, Hayashi Y, Minami M, Tohyama M, Yokota K, Yamada D, Imoto I, Kubo Y. 2017

[学会発表] EBV関連胃癌患者における遊離DNAの有用性の検討

庄田勝俊、市川大輔、藤田悠司、増田清士、濵田隼一、有田智洋、小西博貴、小松周平、塩崎敦、岡本和真、井本逸勢、大辻英吾 2016

[学会発表] 8q13 microdeletion in a Japanese case with mesomelia-synostoses syndrome.

Imoto I, Naruto T, Kohmoto T, Horikawa H, Masuda K. 2016

[学会発表] Long interspersed nuclear element-1 (LINE1)-mediated 8q13 microdeletion detected in a Japanese case with mesomelia-synostoses syndrome.

Imoto I, Naruto T, Kohmoto T, Watanabe M, Ujiro S, Masuda K. 2016

[学会発表] がん体細胞変異検出の特性からみた検査の考え方

井本逸勢 2016

[学会発表] Frequent silencing of the candidate tumor suppressor TSLAC1 by promoter methylation in early stage lung adenocarcinoma.

Kohmoto T, Kajiura K, Naruto T,Masuda K、Kondo K, Tangoku A, Imoto I. 2016

[雑誌論文] A novel frameshift mutation of CHD7 in a Japanese patient with CHARGE syndrome.

Kohmoto T, Shono M, Naruto T, Watanabe M, Suga K, Nakagawa R, Kagami S, Masuda K, Imoto I. 2016

[雑誌論文] A novel missense mutation of COL5A2 in a patient with Ehlers-Danlos syndrome.

Watanabe M, Nakagawa R, Naruto T, Kohmoto T, Suga K, Goji A, Kagami S, Masuda K, Imoto I. 2016

[学会発表] 新規RNA結合蛋白質MRF1は癌関連microRNA発現以上を誘導し食道癌の進展を促進する

藤田悠司、増田清士、井本逸勢 2016

[学会発表] 肺腺癌の早期からDNAメチル化により高頻度に発現抑制を受ける新規癌抑制遺伝子候補TSLAC1の同定

成戸卓也、梶浦耕一郎、増田清士、近藤和也、丹黒章、井本逸勢 2016

[雑誌論文] Exome-first approach identified a novel gloss deletion associated with Lowe syndrome.

Watanabe M, Nakagawa R, Kohmoto T, Naruto T, Suga K, Goji A, Horikawa H, Masuda K, Kagami S, Imoto I. 2016

[学会発表] RNA結合蛋白質TIA1による食道癌進展機構の解明

増田清士、濵田隼一、庄田勝俊、藤田悠司、井本逸勢 2016

[学会発表] ゲノム構造解析を基盤とするがん研究

井本逸勢 2015

[学会発表] アレイ法による網羅的DNAメチル化解析・ゲノム構造解析

井本逸勢 2015

[雑誌論文] HER2 amplification detected in the circulating DNA of patients with gastric cancer: a retrospective pilot study.

Shoda K, Masuda K, Ichikawa D, Arita T, Miyagami Y, Watanabe M, Konishi H, Imoto I, Otsuji E. 2015

[雑誌論文] A FRMD7 variant in a Japanese family causes congenital nystagmus.

Kohmoto T, Okamoto N, Satomura S, Naruto T, Komori T, Hashimoto T, Imoto I. 2015

[学会発表] エクソーム解析で潜在性エクソンを活性化させるGPR143 の深部イントロン変異を検出した眼白子症の家族例

井本逸勢、成戸卓也、増田清士、河本知大、遠藤高生、初川嘉一、岡本伸彦. 2015

[学会発表] Identification of a RNA binding protein, SSP1, inducing cell growth in esophageal squamous cell carcinoma (ESCC)through posttranscriptional regulation of target genes.

Imoto I, Masuda K, Shoda K, Hamada J. 2015

[雑誌論文] Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer

Hosoda F, Arai Y, Okada N, Hiroko Shimizu H, Miyamoto M, Kitagawa N, Katai H, Taniguchi H, Yanagihara K, Imoto I, Inazawa J, Ohki M, Shibata T. 2015

[学会発表] A novel RNA binding protein, SSP1, induced cell growth in squamous cell carcinoma through posttranscriptional regulation.

Masuda K, Shoda K, Hamada J, Imoto I. 2014

[学会発表] Overexpression of SMYD2 contributes to malignant outcome in gastric cancer.

Hirajima S, Komatsu S, Ichikawa D, Nagata H, Nishimura Y, Konishi H, Shiozaki A, Okamoto K, Tsuda H, Imoto I, Inazawa J, Otsuji E. 2014

[雑誌論文] A novel PTCH1 mutation in a patient with Gorlin syndrome.

Okamoto N, Naruto T, Kohmoto T, Komori T, Imoto I 2014

[学会発表] Identification of a novel tumor-suppressor gene through methylome analysis in smoking-associated lung adenocarcinoma.

Imoto I. 2014

[学会発表] HER2 amplification detected in the circulating DNA of patients with gastric cancer: a retrospective pilot study.

Shoda K, Masuda K, Ichikawa D, Arita T, Konishi H, Imoto I, Otsuji E. 2014