研究成果

[学会発表] Possible epigenetic modulation of cerebral angiotensin type 2 receptor in the cognitive function in vascular dementia.

Iwanami J, Mogi M, TsukudaK, Wang XL, Higaki A, Kukida M, Nakaoka H, Yamauchi T, Bai HY, Shan BS, Min LJ, Horiuchi M. 2016

[雑誌論文] Angiotensin II type 2 inhibits vascular intimal proliferation with activation of PPARγ.

Kukida M, Mogi M, Ohshima K, Nakaoka H, Iwanami J, Kanno H, Tsukuda K, Chisaka T, Min LJ, Wang XL, Bai HY, Shan BS, Higaki A, Yamauchi T, Okura T, Higaki J, Horiuchi M. 2016

[学会発表] Deficiency of angiotensin converting enzyme 2 causes deterioration of cognitive function.

Iwanami J, Mogi M, Wang XL, TsukudaK, Higaki A, Kukida M, Nakaoka H, Yamauchi T, Bai HY, Shan BS, Min LJ, Horiuchi M. 2016

[雑誌論文] Drinking citrus fruit juice inhibits vascular remodeling in cuff-induced vascular injury mouse model.

Ohnishi A, Asayama R, Mogi M, Nakaoka H, Kan-no H, Tsukuda K, Chisaka T, Wang XL, Bai HY, Shan BS, Kukida M, Iwanami J, Horiuchi M. 2015

[雑誌論文] Low protein diet-induced fetal growth restriction leads to exaggerated proliferative response to vascular injury in postnatal life.

Chisaka T, Mogi M, Nakaoka H, Kan-no H, Tsukuda K, Wang XL, Bai HY, Shan BS, Kukida M, Iwanami J, Higaki T, Ishii E, Horiuchi M. 2015

[雑誌論文] Role of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis in the hypotensive effect of azilsartan.

Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Jing F, Ohshima K, Chisaka T, Bai HY, Kanno H, Min LJ, Horiuchi M. 2015

[雑誌論文] Angiotensin II type 2 receptor signaing affects dopamine levels in the brain and prevents binge eating disorder.

Nakaoka H, Mogi M, Kan-no H, Tsukuda K, Ohshima K, Wang XL, Chisaka T, Bai HY, Shan BS, Kukida M, Iwanami J, Horiuchi M. 2015

[図書] THE PROTECTIVE ARM OF THE RENIN ANGIOTENSIN SYSTEM(RAS)

Horiuchi M, Mogi M 2015

[雑誌論文] Direct stimulation of angiotensin II type2 receptor initiated after stroke ameliorates ischemic brain damage.

Min LJ, Mogi M, Tsukuda K, Jing F, Ohshima K, Nakaoka H, Kanno H, Wang XL, Chisaka T, Bai HY, Iwanami J, Horiuchi M. 2014

[雑誌論文] Serum levels of renin-angiotensin system components in acute stroke patients.

Mogi M, Kawajiri M, Tsukuda K, Matsumoto S, Yamada T, Horiuchi M. 2014

[雑誌論文] Role of angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis in the hypotensive effect of azilsartan.

Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Jing F, Ohshima K, Chisaka T, Bai HY, Kanno H, Min LJ, Horiuchi M. 2014

[学会発表] アンジオテンシンIIタイプ2受容体直接刺激はPPAR-gamma活性化を伴って血管リモデリングを抑制する

大島弘世、茂木正樹、中岡裕智、閔莉娟、菅野晴美、佃架奈、千坂俊行、Huiyu Bai、王小俐、岩波純、大木元明義、檜垣實男、堀内正嗣 2013

[学会発表] ACE2/Angiotensin-(1-7)/ Mas axis plays an important role on cognitive function using ACE2-deficient mice.

王小俐、茂木正樹、岩波純、閔莉娟、佃架奈、中岡裕智、白薈鈺、菅野晴美、大島弘世、千阪俊行、堀内正嗣 2013

[学会発表] AT2受容体刺激は慢性脳低灌流による認知機能低下を改善する

岩波純、堀内正嗣 2013

[学会発表] Possible Synergistic Effect of Direct Angiotensin II Type 2 Receptor Stimulation by Compound 21 with Memantine on Cognitive Impairment in Type 2 Diabetic Mouse

Mogi M, Iwanami J, Nakaoka H, Tsukuda K, Ohshima K, Fei J, Wang XL, Chisaka T, Min LJ and Horiuchi M. 2013

[学会発表] Direct Angiotensin II Type 2 Receptor Stimulation by Compound 21 Prevents Vascular Dementia; Involvement of NMDA Receptor Activation

Mogi M, Iwanami J, Min LJ Fei J, Tsukuda K, Ohshima K, Nakaoka H, Wang XL, Chisaka T, and Horiuchi M 2013

[学会発表] Gain of function approach by angiotensin-(1-7) to cognitive decline in ACE2 deficient mice.

Wang XL, Mogi M, Iwanami J, Tsukuda K, Min LJ, Nakaoka H, Bai H, Ohshima K, Chisaka T, Horiuchi M 2013

[学会発表] 血管リモデリングにおけるACE2/アンジオテンシン（1-7）/ Mas系とアンジオテンシン（1-7）/ アンジオテンシンIIタイプ2受容体系のクロストーク

大島弘世、茂木正樹、中岡裕智、菅野晴美、佃架奈、千坂俊行、Huiyu Bai、王小俐、閔莉娟、岩波純、大木元明義、檜垣實男、堀内正嗣 2013

[学会発表] Possible roles of crosstalk between angiotensin-converting enzyme 2/ Angiotensin (1-7)/ Mas Axis and Angiotensin (1-7) angiotensin II type 2 receptor axis in vascular remodeling

Ohshima K, Mogi M, Nakaoka H, Iwanai J, Min LJ, Tsukuda K, Kanno H, Chisaka T, Wang XL, Ogimoto A, Higaki J, Horiuchi M 2013

[学会発表] Intrauterine growth restriction is a risk of vascular remodeling

Chisaka T, Mogi M, Nakaoka H, Ohshima K, Kan-no H, Tsukuda K, Wang XL, Bai H, Min LJ, Iwanami J, Horiuchi M 0

[学会発表] Synergistic inhibitory effect of rosuvastatin and an AT2 receptor agonist on vascular remodeling

Bai H, Mogi M, Nakaoka H, Kan-no H, Tsukuda K, Ohshima K, Chisaka T, Wang XL, Min LJ, Iwanami J, Horiuchi M 0

[学会発表] Effect of interferon regulatory factor-1 on vascular dementia using mouse chronic cerebral hypoperfusion model

Wang XL, Iwanami J, Mogi M, Tsukuda K, Nakaoka H, Bai HY, Kukida M, Chisaka T, Shan BS ,Horiuchi M 0

[学会発表] Angiotensin II type2 receptor interacting protein inhibits vascular remodeling with activation of perpxispme proliferator-activated receptor gamma

Ohshima K, Mogi M, Nakaoka H, Iwanami J, Min LJ, Kan-no H, Tsukuda K, Chisaka T, Bai H, Wang XL, Ogimoto A, Higaki J, Horiuchi M 0

[学会発表] 中大脳動脈梗塞モデルにおけるAT2受容体直接刺激薬の脳保護効果

閔莉娟、茂木正樹、佃架奈、中岡裕智、王小俐、千阪俊行、茎田昌敬、白薈鈺、単宝帥、岩波純、堀内正嗣 0

[学会発表] 柑橘飲料飲用による血管障害抑制効果（炎症性血管障害モデルマウスにおける検討）

大西亜里香、浅山理恵、茂木正樹、中岡裕智、菅野晴美、千阪俊行、莖田昌敬、岩波純、堀内正嗣 0

[学会発表] Hypotensive mechanism of telmisartan in high salt-loading human renin and angiotensinogen transgenic mice

Iwanami J, Mogi M, Tsukuda K, Wang XL, Ohshima K, Nakaoka H, Chisaka T, Bai H, Min LJ, Horiuchi M 0

[学会発表] Direct angiotensin II type 2 receptor stimulation by compound 21 prevents vascular dementia

Iwanami J, Mogi M, Tsukuda K, Wang XL. Kukida M, Nakaoka H, Chisaka T, Bai HY, Shan BS, Horiuchi M 0

[学会発表] Improved cognitive function by angiotensin-(1-7) in ace2ko mice

Wang XL, Iwanami J, Min LJ, Nakaoka H, Tsukuda K, Bai H, Ohshima K, Chisaka T, Mogi M, Horiuchi M 0

[学会発表] インターフェロン調節因子1（IRF-1）はアンジオテンシンII2型受容体の発現を調節し、炎症性血管リモデリングを抑制する

中岡裕智、茂木正樹、菅野晴美、佃架奈、千阪俊行、莖田昌敬、王小俐、Bai Huiyu、単宝帥、岩波純、鈴木純、堀内正嗣 0

[学会発表] Gain-of-function of cognitive impairment by angiotensin-(1-7)in ACE deficient mice

Wang XL, Mogi M, Iwanami J, Tsukuda K, Min LJ, Nakaoka H, Bai HY, Ohshima K, Chisaka T, Horiuchi M 0