トップ研究者を探す脳動脈瘤形成増大における体内塩分貯留の意義と分子機序

脳動脈瘤形成増大における体内塩分貯留の意義と分子機序

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-24592131
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
脳神経外科学
研究機関 徳島大学
代表研究者 里見 淳一郎
研究分担者 永廣 信治
研究分担者 多田 恵曜
研究分担者 兼松 康久
研究期間 開始年月日 2012/4/1
研究期間 終了年度 2014
研究ステータス 完了 (2014/4/1)
配分額(合計) 5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
配分額(履歴) 2014年度:650,000 (直接経費 :500,000、間接経費 :150,000)
2013年度:2,730,000 (直接経費 :2,100,000、間接経費 :630,000)
2012年度:1,950,000 (直接経費 :1,500,000、間接経費 :450,000)
キーワード 脳・神経
脳血管病
エストロゲン
高塩分摂取
高血圧
体内塩分貯留
脳動脈瘤破裂
ミネラルコルチコイド受容体
脳神経疾患
脳動脈瘤
ミネラルコルチコイド

研究成果

[雑誌論文] Prevention of Retrograde Blood Flow Into Large or Giant Internal Carotid Artery Aneurysms by Endovascular Coil Embolization with High-Flow Bypass: Surgical Technique and Long-Term Results

Nakajima N, Nagahiro S, Satomi J, Tada Y, Nakajima K, Sogabe S, Hanaoka M, Matsubara S, Uno M, Satoh K 2015

[雑誌論文] Two-layered susceptibility vessel sign on 3-tesla T2*-weighted imaging is a predictive biomarker of stroke subtype

Yamamoto N, Satomi J, Tada Y, Harada M, Izumi Y, Nagahiro S, Kaji R 2015

[雑誌論文] Intra-arterial signal on arterial spin labeling perfusion MRI to identify the presence of acute middle cerebral artery occlusion

Tada Y, Satomi J, Abe T, Kuwayama K, Sogabe S, Fujita K, Yamamoto N, Kaji R, Harada M, Nagahiro S 2014

[雑誌論文] Acquired Pial and Dural Arteriovenous Fistulae following Superior Sagittal Sinus Thrombosis in Patients with Protein S Deficiency: A Report of Two Cases

Matsubara S, Satoh K, Satomi J, Shigekiyo T, Kinouchi T, Miyake H, Nagahiro S 2014

[雑誌論文] Is the Susceptibility Vessel Sign on 3-Tesla Magnetic Resonance T2*-Weighted Imaging a Useful Tool to Predict Recanalization in Intravenous Tissue Plasminogen Activator?

Yamamoto N, Satomi J, Harada M, Izumi Y, Nagahiro S, Kaji R 2014

[雑誌論文] Brush sign on 3-T T2*-weighted MRI as a potential predictor of hemorrhagic transformation after tissue plasminogen activator therapy

Terasawa Y, Yamamoto N, Morigaki R, Fujita K, Izumi Y, Satomi J, Harada M, Nagahiro S, Kaji R 2014

[学会発表] Role of hyperhomocysteinemia in the development of intracranial aneurysms

Korai M, Kung DK, Kitazato KT, Matsushita N, Tada Y, Yagi K, Shimada K, Kanematsu Y, Satomi J, Nagahiro S 2013

[雑誌論文] Frequency of emerging positive diffusion-weighted imaging in early repeat examinations at least 24 h after transient ischemic attacks

Morita N, Harada M, Satomi J, Terasawa Y, Kaji R, Nagahiro S 2013

[学会発表] Hemodynamic change elicits the formation and rupture of experimental cerebral aneurysms

Miyamoto T, David K. Kung, Korai M, Kitazato KT, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S 0

[学会発表] Role of hyperhomocysteinemia in the development of intracranial aneurysms

Korai M, Kitazato KT, Miyamoto T, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S 0

[学会発表] Hemodynamic changes may elicit the formation and rupture of experimental cerebral aneurysms

Miyamoto T, David K. Kung, Korai M, Kitazato KT, Shimada K, Yagi K, Tada Y, Kurashiki Y, Kuwayama K, Satomi J, Nagahiro S 0

[学会発表] Is the regulation of M1 macrophage activation beneficial in the acute phase of post cerebral ischemia?

Kurashiki Y, Kitazato K, Uto Y, Yagi K, Shimada K, Miyamoto T, Sumiyoshi M, Tada Y, Kuwayama K, Satomi J, Nagahiro S 0

[学会発表] Activation of M2 macrophage in the late phase after cerebral ischemia promotes the expression of neurogenesis related molecules

Kurashiki Y, Kitazato K1, Uto Y, Yagi K, Shimada K, Miyamoto T1, Sumiyoshi M, Tada Y, Kuwayama K, Satomi J, Nagahiro S 0