研究成果

[雑誌論文] Significance of exercise in nonalcoholic fatty liver disease in men: a community-based large cross-sectional study.

Miyake T, Kumagi T, Hirooka M, Furukawa S, Kawasaki K, Koizumi M, Todo Y, Yamamoto S, Nunoi H, Tokumoto Y, Ikeda Y, Abe M, Kitai K, Matsuura B, Hiasa Y. 2015

[雑誌論文] Interleukin 28B polymorphism predicts interferon plus ribavirin treatment outcome in patients with hepatitis C virus-related liver cirrhosis: A multicenter retrospective study in Japan.

Shakado S, Sakisaka S, Okanoue T, Chayama K, Izumi N, Toyoda J, Tanaka E, Ido A, Takehara T, Yoshioka K, Hiasa Y, Nomura H, Seike M, Ueno Y, Kumada H. 2014

[雑誌論文] 18F-FDG-PET/CT predicts the distribution of microsatellite lesions in hepatocellular carcinoma.

Ochi H, Hirooka M, Hiraoka A, Koizumi Y, Abe M, Sogabe I, Ishimaru Y, Furuya K, Miyagawa M, Kawasaki H, Michitaka K, Takada Y, Mochizuki T, Hiasa Y. 2014

[雑誌論文] Maximum standardized uptake value in 18F-fluoro-2-deoxyglucose positron emission tomography is associated with advanced tumor factors in esophageal cancer.

Kajiwara T, Hiasa Y, Nishina T, Matsumoto T, Hori S, Nadano S, Iguchi H, Takeji S, Tsubouchi E, Ikeda Y, Onji M. 2014

[雑誌論文] Short sleep duration reduces the risk of nonalcoholic fatty liver disease onset in men: a community-based longitudinal cohort study.

Miyake T, Kumagi T, Furukawa S, Hirooka M, Kawasaki K, Koizumi M, Todo Y, Yamamoto S, Tokumoto Y, Ikeda Y, Abe M, Kitai K, Matsuura B, Hiasa Y. 2014

[雑誌論文] Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion.

Kuroda T, Hirooka M, Koizumi M, Ochi H, Hisano Y, Bando K, Matsuura B, Kumagi T, Hiasa Y. 2014

[雑誌論文] Wilms' tumor 1 gene modulates Fas-related death signals and anti-apoptotic functions in hepatocellular carcinoma.

Uesugi K, Hiasa Y, Tokumoto Y, Mashiba T, Koizumi Y, Hirooka M, Abe M, Matsuura B, Onji M. 2013

[学会発表] Nature of pathogenic and protective immunity in chronic hepatitis B virus infection

Sheikh Mohammad Fazle Akbar, Mamun A. Mahtab, Yoichi Hiasa, Julio Cesar Aguilar 2013

[雑誌論文] Des-gamma-carboxy prothrombin identified by P-11 and P-16 antibodies reflects prognosis for patients with hepatocellular carcinoma.

Takeji S, Hirooka M, Koizumi Y, Tokumoto Y, Abe M, Ikeda Y, Nadano S, Hiasa Y, Onji M. 2013

[学会発表] IgG4関連疾患診断における巻組織検査の有用性

熊木天児、日浅陽一、恩地森一 2013

[学会発表] Composition of serum fatty acids may be associated with the antiviral effects of interferon-based therapy in patients with hepatitis C virus infection

Teruki Miyake, Masashi Hirooka, Yoshio Tokumoto, Takao Watanabe, Teru Kumagi, Masanori Abe, Shinya Furukawa, Morikazu Onji, Bunzo Matsuura, Yoichi Hiasa 2013

[学会発表] Protein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infection

Takao Watanabe, Yoshio Tokumoto, Masashi Hirooka, Masanori Abe, Morikazu Onji, Raymond T. Chung, Yoichi Hiasa 2013

[学会発表] A phase III clinical trial with a therapeutic vaccine containing both HBsAg and HBcAg administered via both mucosal and parenteral routes in patients with chronic hepatitis B

Sheikh Mohammad Fazle Akbar, Mamun A. Mahtab, Salimur Rahman, Julio Cesar Aguilar, Yoichi Hiasa, Shunji Mishiro 2013

[雑誌論文] B cell activating factor in obesity is regulated by oxidative stress in adipocytes

Tada F, Abe M, Kawasaki K, Miyake T, Shiyi C, Hiasa Y, Matsuura B, Onji M. 2013

[雑誌論文] Protein kinase R modulates c-Fos and c-Jun signaling to promote proliferation of hepatocellular carcinoma with hepatitis C virus infection.

Watanabe T, Hiasa Y, Tokumoto Y, Hirooka M, Abe M, Ikeda Y, Matsuura B, Chung RT, Onji M. 2013

[学会発表] 新しいPIVKA-II分画(NX-PVKA)の肝細胞癌患者予後との関連

竹治智、廣岡昌史、日浅陽一 2013

[学会発表] Insertion of LINE-1 retrotranspozon in SLCO1B3 gene causes Rotor syndrome in Japanese patients

Tatehiro Kagawa, Kazuya Anzai, Kota Tsuruya, Yoshitaka Arase, Shunji Hirose, Koichi Shiraishi, Tsuneo Kitamura, Yoshinao Kobayashi, Yoichi Hiasa, Tetsuya Mine 2013

[学会発表] Virtual ultrasonography constructed by Gd-EOB- DTPA-enhanced magnetic resonance imaging is useful to avoid bile duct injury during radiofrequency ablatio

Yohei Koizumi, Masashi Hirooka, Hironori Ochi, Yoshio Tokumoto, Masanori Abe, Fujimasa Tada, Atsushi Hiraoka, Hiroaki Tanaka, Takaharu Tsuda, Teruhito Mochizuki, Yoichi Hiasa 2013

[学会発表] 治療前CTHA後期相を用いたfusion CTによる肝細胞癌局所療法治療効果判定

廣岡昌史、小泉洋平、日浅陽一 2013

[学会発表] 新たなPIVKA-II分画(NX-PVKA)の肝癌患者予後予測における臨床的有用性

竹治智、廣岡昌史、日浅陽一 2013

[学会発表] Rapid absorption of dietary long-chain fatty acids with changes to intestinal fatty acid transporters in liver cirrhosis

Yasunori Yamamoto, Yoshio Ikeda, Eiji Tsubouchi, Hiroki Utsunomiya, Miyake Teruki, Hiroaki Nunoi, Morikazu Onji, Bunzo Matsuura, Yoichi Hiasa 2013

[学会発表] Trans-ethnic analyses of HLA-DPA1, DPB1 haplotypes to be associated with hepatitis B virus infection

Nao Nishida, Hiromi Sawai, Kouichi Kashiwase, Mutsuhiko Minami, Yoichi Hiasa, et al. 2013

[図書] 新薬展望2014「消化器疾患治療薬」

廣岡昌史、池田宜央、日浅陽一 2013

[雑誌論文] Wilms' tumor 1 gene modulates Fas-related death signals and anti-apoptotic functions in hepatocellular carcinoma.

Uesugi K, Hiasa Y, Tokumoto Y, Mashiba T, Koizumi Y, Hirooka M, Abe M, Matsuura B, Onji M. 2013

[図書] Bio Clinica 「7 DAAによる治療困難例への挑戦、肝移植例　他」

徳本良雄、日浅陽一 2013

[雑誌論文] Importance of screening for synchronous malignant neoplasms in patients with hepatocellular carcinoma: impact of FDG PET/CT.

Hiraoka A, Hirooka M, Ochi H, Koizumi Y, Shimizu Y, Shiraishi A, Yamago H, Tanihira T, Miyata H, Ninomiya T, Kawasaki H, Ishimaru Y, Sogabe I, Inoue T, Abe M, Hiasa Y, Matsuura B, Onji M, Michitaka K. 2013

[学会発表] An isoform of des-gamma-carboxy prothrombin (NX-PVKA) is a prognostic marker of hepatocellular carcinoma

Satoru Takeji, Masashi Hirooka, Yohei Koizumi, Hironori Ochi, Yoshio Tokumoto, Fujimasa Tada, Masanori Abe, Morikazu Onji, Yoichi Hiasa 2013

[雑誌論文] Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma.

Tada F, Abe M, Hirooka M, Ikeda Y, Hiasa Y, Lee Y, Jung NC, Lee WB, Lee HS, Bae YS, Onji M. 2012

[図書] Dendritic Cells in Autoimmune Liver Diseases.

Abe M, Hiasa Y, Onji M 2012

[雑誌論文] Real-time tissue elastography for evaluation of hepatic fibrosis and portal hypertension in nonalcoholic fatty liver diseases.

Ochi H, Hirooka M, Koizumi Y, Miyake T, Tokumoto Y, Soga Y, Tada F, Abe M, Hiasa Y, Onji M. 2012

[学会発表] 薬物性肝障害の実態

堀池典生、上杉和寛、日浅陽一 2012

[学会発表] 肝硬変患者における脂肪酸吸収変化とglycosylated CD36の役割

山本安則、池田宜央、日浅陽一 2012

[学会発表] 肝細胞癌に対する抗原パルス樹状細胞を用いた免疫療法の第I/II相臨床試験

阿部雅則、多田藤政、廣岡昌史、小泉洋平、日浅陽一、恩地森一 2012

[図書] Dendritic Cell-Based Immune Therapy in Liver Diseases.

Akbar SMF, Hiasa Y, Mahtab MAI, Onji M 2012

[図書] 愛媛大学における急性肝炎症例の解析 わが国における急性肝炎の現状　全国調査2008-2011

徳本良雄、渡辺崇夫、多田藤政、上杉和寛、眞柴寿枝、重松秀一郎、阿部雅則、日浅陽一、恩地森一 2012

[学会発表] NAFLDの肝線維化診断におけるReal-time tissue elastographyの有用性の検討

越智裕紀、廣岡昌史、日浅陽一 2012

[雑誌論文] Rapid alternative absorption of dietary long-chain fatty acids with upregulation of intestinal glycosylated CD36 in liver cirrhosis.

Yamamoto Y, Hiasa Y, Murakami H, Ikeda Y, Yamanishi H, Abe M, Matsuura B, Onji M. 2012

[学会発表] Branched-chain amino acids improve intestinal malabsorption of dietary long-chain fatty acids and preserve intestinal fatty acid transporters in liver cirrhosis.

Yamamoto Y, Utsunomiya H, Hiasa Y, et al. 0

[学会発表] Wisteria floribunda agglutinin-positive Mac-2 binding protein as a predictor of liver fibrosis in patients with non-alcoholic fatty liver disease.

Abe M, Miyake T, Hiasa Y, et al. 0

[学会発表] Oral glucose tolerance test predicts hepatic fibrosis in nonalcoholic fatty liver disease patients without overt diabetes mellitus.

Nishina S, Hyogo H, Hiasa Y, et al. 0

[学会発表] Pancreatic congestion in liver cirrhosis correlates with impaired insulin secretion.

Kuroda T, Hirooka M, Hiasa Y, et al. 0

[学会発表] Portal hypertension due to outflow block in non-cirrhotic patients with nonalcoholic fatty liver disease.

Koizumi Y, Hirooka M, Hiasa Y, et al. 0

ROMスコア及び肝細胞癌患者の客観的な予後予測方法

体内での針先端を画像上に表示する針先端画像表示装置、それを用いたがん治療装置および体内での針先端を画像上に表示する針先端画像表示方法