研究成果

[雑誌論文] Chharacteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis

Matsushita T, Tateishi T, Isobe N, Yonekawa T, Yamasaki R, Murai H, Kira J 2013

[雑誌論文] 視神経脊髄炎、多発性硬化症、Balo病におけるアストロサイト障害の特徴

松下拓也、真崎勝久、鈴木諭、松岡健、米川智、呉暁牧、岩城徹、吉良潤一 2013

[雑誌論文] Clinical relevance of serum aquaporin-4 levels in neuromyelitis optica

Isobe N, Yonekawa T, Matsushita T, Masaki K, Yoshimura S, Fichna J, Chen S, Furmania K, Smith BR, Kira J 2013

[雑誌論文] Chharacteristic cerebrospinal fluid cytokine/chemokine profiles in neuromyelitis optica, relapsing remitting or primary progressive multiple sclerosis.

Matsushita T, Tateishi T, Isobe N, Yonekawa T, Yamasaki R, Murai H, Kira J: 2013

[雑誌論文] Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin-4 antibody status

Yoshimura S*, Isobe N*, Matsushita T, Yonekawa T, Masaki K, Sato S, Kawano Y, Kira J 2013

[雑誌論文] 第4回多発性硬化症全国臨床疫学調査による日本における多発性硬化症の治療実態の解析

松下拓也、吉村怜、小副川学、吉良潤一: 2013

[雑誌論文] A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese.

Huang J, Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Sato S, Yamasaki R, Kira J: 2013

[雑誌論文] Extensive loss of connexins in Balo's disease: evidence for an auto- antibody- independent astrocytopathy via impaired astrocyte-oligodendrocyte/myelin interaction

Masaki K, Suzuki SO, Matsushita T, Yonekawa T, Matsuoka T, Isobe N, Motomura K, Wu XM, Tabira T, Iwaki T, Kira J 2012

[雑誌論文] HLA-DPB1* 0201 is associated with susceptibility to atopic myelitis in Japanese.

Sato S, Isobe N, Yoshimura S, Kanamori Y, Masaki K, Matsushita T, Kira J: 2012

[学会発表] Early disruption of astrocytic connexins in multiple sclerosis, Balo’s disease and neuromyelitis optica

Masaki K、Suzuki SO、Matsushita T、Matsuoka T、Suzuki M、Suenaga T、Tabira T、Iwaki T、Kira J 2012

[雑誌論文] Clinical disability progression and platelet GP IIb/IIIa values in patients with atopic myelitis

Gulibahaer A, Yamashita K, Torii T, Furuta K, Isobe N, Matsushita T, Masaki K, Matsumoto S, Kira J: 2012

[雑誌論文] Genetic and infectious profiles of Japanese multiple sclerosis patients

Yoshimura S, Isobe N, Yonekawa T, Matsushita T, Masaki K, Sato S, Kawano Y, Yamamoto K, Kira J 2012

[学会発表] istinct HLA polymorphisms among atopic myelitis, multiple sclerosis and neuromyelitis optica patients in Japan.

Sato S、Isobe N、Yoshimura S、Kanamori Y、Masaki K、Matsushita T、Kira J、 and the South Japan Multiple Sclerosis Genetics Consortium (SJMSGC) 2012

[学会発表] 日本人多発性硬化症 (MS)患者でも髄液IgG産生異常は、HLA-DRB1*1501アリルとBarkhof基準を満たす脳MRI病巣に有意に相関する

吉村怜、磯部紀子、米川智、佐藤眞也、眞﨑勝久、松下拓也、吉良潤一 2012

[学会発表] NOTCH4 missense mutation and HLA class II gene in Japanese patients with multiple sclerosis

Huang J, Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Kira J 2012

[学会発表] 多発性硬化症、視神経脊髄炎、アトピー性脊髄炎のHLA遺伝子多型の差異.

佐藤眞也、吉村怜、米川智、磯部紀子、金森祐治、眞﨑勝久、松下拓也、吉良潤一 2012

[学会発表] Interferon-beta reduces peripheral blood IFN-γ and IL-17-producing T cells in patients with multiple sclerosis.

Song ZY、Doi H、Yoshimura S、Tateishi T、Yonekawa T、Matsushita T、Kira J 2012

[学会発表] 日本人脱髄性疾患に影響する遺伝的要因と環境中の普遍的な感染性要因の同定

吉村怜、磯部紀子、米川智、佐藤眞也、眞﨑勝久、松下拓也、吉良潤一: 日本人脱髄 2012

[学会発表] 脱髄性疾患における広汎なコネキシン脱落と病態への関与.

眞﨑勝久、鈴木諭、松下拓也、松岡健、鈴木万幾子、 末長敏彦、田平武、岩城徹、吉良潤一: 2012

[学会発表] 多発性硬化症、視神経脊髄炎、Balo病における広汎なコネキシン蛋白の脱落と病態への関与

眞﨑勝久、鈴木諭、松下拓也、松岡健、米川智、磯部紀子、田平武、岩城徹、吉良潤一 2012

[学会発表] 日本人多発性硬化症の遺伝的要因と環境要因の相互作用

吉村怜、磯部紀子、松下拓也、米川智、眞﨑勝久、佐藤眞也、吉良潤一 2012

[学会発表] Relationship Between Human Leukocyte Antigen Polymorphisms and Disease Susceptibility in Japanese Patients with Multiple Sclerosis, Neuromyelitis Optica, or Atopic Myelitis.

Sato S、Yoshimura S、Yonekawa T、Isobe N、Kanamori Y、Masaki K、Matsushita T、Kira J 2012

[学会発表] Connexin astrocytopathy in multiple sclerosis, Balo’s disease and neuromyelitis optica.

Masaki K、Suzuki SO、Matsushita T、Matsuoka T、Suenaga T、Tabira T、Iwaki T、Kira J 2012

[雑誌論文] Comparison of clinical, immunological and neuroimaging features between anti-aquaporin-4 antibody-positive and -negative Sjogren's syndrome patients with central nervous system manifestations

Riwanti Estiasari, Matsushita T, Masaki K, Akiyama T, Yonekawa T, Isobe N, Kira J 2012

[雑誌論文] Quantitative assays for anti-aquaporin-4 antibody with subclass analysis in neuromyelitis optica

Isobe N, Yonekawa T, Matsushita T, Kawano Y, Masaki K, Yoshimura S, Fichna J, Chen S, Furmaniak J, Smith BR, Kira J 2012

[学会発表] Reappraisal of longitudinally extensive spinal cord lesions by 3-tesla MRI in anti-AQP4 antibody-seropositive and -seronegative NMO and MS patients.

Yonekawa T、Masaki K、Isobe N、Yoshimura S、Matsushita T、Kira J 2012

[学会発表] Distinct genetic and infectious profiles between multiple sclerosis and neuromyelitis optica in Japanese patients.

Yoshimura S、Yonekawa T、Isobe N、Masaki K、Sato S、Matsushita T、Kira J 2012

[雑誌論文] First diagnostic criteria for atopic myelitis with special reference to discrimination from myelitis-onset multiple sclerosis.

Isobe N, Kanamori Y, Yonekawa T, Matsushita T, Shigeto H, Kawamura N, Kira J: 2012

[学会発表] Dysregulation of surface marker expressions on peripheral monocytes in multiple sclerosis.

Cui YW、Masaki K、Yamasaki R、 Tateishi T、Matsushita T、Shi N、Ohyagi Y、Kira J 2012

[雑誌論文] Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians

Fang L*, Isobe N*, Yoshimura S, Yonekawa T, Matsushita T, Masaki K, Doi H, Ochi K, Miyamoto K, Kawano Y, Kira J 2011

[雑誌論文] T cell reactivities to myelin protein-derived peptides in neuromyelitis optica patients with anti-aquaporin-4 antibody

Yonekawa T, Matsushita T, Minohara M, Isobe N, Masaki K, Yoshimura S, Nishimura S, Kira J 2011

[雑誌論文] SNP based analysis of the HLA locus in Japanese multiple sclerosis patients

McElroy JP, Isobe N, Gourraud PAFD, Cailler GSJ, Matsushita T, Kohriyama T, Miyamoto K, Nakatsuji Y, Miki T, Hauser SL, Oksenberg JR, Kira J 2011

[雑誌論文] Analysis of cerebrospinal fluid cytokines and growth factors in multiple sclerosis patients with and without chronic headaches

DoiH,MatsushitaT,IsobeN,TateishiT,KiraJ 2011

[雑誌論文] Longitudinally extensive myelopathy in Caucasians: a West Australian study of 26 cases from the Perth Demyelinating Diseases Database

Qiu W, Wu JS, Zhang MN, Matsushita T, Kira J, Carroll WM, Mastaglia L, Kermode AG 2010

[雑誌論文] Reappraisal of brain MRI features in multiple sclerosis and neuromyelitis optica patients according to anti-aquaporin-4 antibody status

Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, Masaki K, Yoshimura T, Yamasaki R, Ohyagi Y, Kira J 2010

[雑誌論文] CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity

Matsushita T, Isobe N, Kawajiri M, Mogi M, Tsukada K, Horiuchi M, Yamasaki R, Ohyagi Y, Kira J 2010

[雑誌論文] Influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis in Japanese patients with respect to anti-aquaporin 4 antibody status.

Isobe N, Matsushita T, Yamasaki R, Ramagopalan SV, Kawano Y, Nishimura Y, Ebers GC, Kira J 2010

[雑誌論文] Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis

Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Matsuoka T, Minohara M, Kira J 2010

[雑誌論文] B-cell activating factor of the TNF family isup-regulated in neuromyelitis optica

Okada K, Matsushita T, Kira J, Tsui S 2010

[雑誌論文] A NOTCH4 missense mutation confers resistance to multiple sclerosis in Japanese

Huang J, Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Sato S, Yamasaki R, Kira J