研究成果

[学会発表] 神経障害性疼痛・片頭痛特異的髄液分子マーカーの同定

土井光, 松下拓也, 河村信利, 吉良潤一 2011

[学会発表] 多発性硬化症・視神経脊髄炎におけるサイトカイン/ケモカイン動態

松下拓也 2011

[学会発表] 多発性硬化症・視神経脊髄炎におけるサイトカイン/ケモカイン動態.

松下拓也, 河村信利, 立石貴久, 吉良潤一 2011

[雑誌論文] Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis.

松下拓也, ら 2010

[学会発表] Extensive Aquaporin-4 (AQP4) Loss in Balo's Concentric Sclerosis in The Absence of Anti-AQP4 Antibody.

Masaki K, Matsuoka T, Suzuki SO, Wu XM, Zhang KN, Yonekawa T, Isobe N, Ordinario AT, Tabira T, Iwaki T, Matsushita T, Kira J 2010

[学会発表] Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risks in Asians .

Isobe N, Fang L, Yoshimura S, Yonekawa T, Matsushita T, Masaki K, Doi H, Kira J 2010

[雑誌論文] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitis optica according to anti-aquaporin-4 antibody status.

松下拓也, ら 2010

[学会発表] Non-NMO MS とNMOにおけるHLA-DRB1 アリル間のepistaticinteraction 解析.

磯部紀子, 松下拓也, 松岡健, 米川智, 眞崎勝久, Ramagopalan SV, Ebers GC, 西村泰治, 吉良潤一 2010

[学会発表] 脱髄疾患におけるCLDND1 の病理学的検討.

真崎勝久, 三野原元澄, 米川智, 磯部紀子, 松下拓也, 吉良潤一 2010

[雑誌論文] Influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis inJapanese patients with respect to anti-aquaporin 4 anttttibody status.

Isobe N, Matsushita T, Yamasaki R, Ramagopalan SV, Kawano Y, Nishimura Y, Ebers GC, Kira J 2010

[雑誌論文] Induction of paranodal myelin detachment and sodium channel loss in vivo by Campylobacter jejuni DNA-binding protein from starved cells (C-Dps) in myelinated nerve fibers.

Piao H, Minohara M, Kawamura N, Li W, Mizunoe Y, Umehara F, Goto Y, Kusunoki S, Matsushita T, Ikenaka K, Maejima T, Nabekura J, Yamasaki R, Kira J 2010

[学会発表] Cytokine/chemokine profile of Japanese multiple sclerosis and neuro myelitis optica patients with or without anti-AQP4 antibody.

松下拓也 2010

[雑誌論文] CSF chemokine alterations related to the clinical course of amyotrophic lateral sclerosis.

松下拓也, ら 2010

[雑誌論文] B-cell activating factor of the TNF family is up-regulated in neuromyelitis optica.

Okada K, Matsushita T, Kira J, Tsuji S 2010

[学会発表] 頭部病巣の有無による視神経脊髄炎の臨床的特徴の比較

松下拓也, 磯部紀子, 松岡健, 眞崎勝久, 米川智, 吉良潤一 2010

[学会発表] Extensive Aquaporin-4 (AQP4) Loss In Balo's Concentric Sclerosis In The Absence Of Anti-AQP4 Antibody.

Masaki K, Matsuoka T, Suzuki SO, Wu XM, Zhang KN, Yonekawa T, Isobe N, Ordinario AT, Tabira T, Iwaki T, Matsushita T, Kira J 2010

[雑誌論文] Oscillatory gamma synchronization binds the primary and secondary somatosensory areas in humans.

Hagiwara K, Okamoto T, Shigetou H, Ogata K, Somehara Y, Matsushita T, Kira J, Tobimatsu S 2010

[学会発表] 中枢神経障害を有するシェーグレン症候群と抗aquaporin-4(AQP4)抗体

松下拓也 2010

[学会発表] Cytokine/chemokine profile of Japanese multiple sclerosis and neuromyelitis optica patients with or without anti-AQP4 antibody

Matsushita T, Isobe N, Yonekawa T, Shi N, Tateishi T, Kira J 2010

[学会発表] 多発性硬化症に対するインターフェロンβ 導入による脳脊髄液サイトカインへの影響.

土井光, 松下拓也, 立石貴久, 磯部紀子, 大八木保政, 吉良潤一 2010

[雑誌論文] Oscillatory gamma synchronization billds the primary and secondary so matosensory areas in humans.

松下拓也, ら 2010

[学会発表] 神経性疼痛・片頭痛特異的 髄液分子マーカーの同定

土井光, 松下拓也, 河村信利, 吉良潤一 2010

[雑誌論文] CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4autoimmunity.

Matsushita T, Isobe N, Kawajiri M, Mogi M, Tsukada K, Horiuchi M, Yamasaki R, Ohyagi Y, Kira J 2010

[雑誌論文] Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis.

Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Matsuoka T, Minohara M, Kira J 2010

[学会発表] 中枢神経障害を有するシェーグレン症候群と抗aquaporin-4(AQP4)抗体.

松下拓也, 眞崎勝久, 米川智, 磯部紀子, 松岡健, 吉良潤一 2010

[学会発表] Non-NMO MS とNMOにおけるHLA-DRB1 アリル間のepistaticinteraction 解析.

磯部紀子, 松下拓也, 松岡健, 米川智, 真崎勝久, Ramagopalan SV, Ebers GC, 西村泰治, 吉良潤一 2010

[学会発表] Usefulness of flowcytometry and enzyme-linked immunosorbent assay for detecting anti-aquaporin-4antibody.

Isobe N, Yonekawa T, Matsushita T, Kawano Y, Masaki K, Chen S, Smith B R, Kira J 2010

[学会発表] The influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis with respect to the criteria of neuromyelitis optica(ポスター)

Isobe N, Matsushita T, Yamasaki R, Ramagopalan S.V., Kawano Y, Nishimura Y, Ebers G.C., Kira J 2010

[雑誌論文] Longitudinally extensive myelopathy in Caucasians: a West Australian study of 26 cases from the Perth Demyelinating Diseases Database.

Qiu W, Wu JS, Zhang MN, Matsushita T, Kira J, Carroll WM, Mastaglia L, Kermode AG 2010

[学会発表] CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity.

Matsushita T, Isobe N, Kawajiri M, Mogi M, Tsukuda K, Horiuchi M, Kira J 2010

[学会発表] The influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis with respect to the criteria of neuromyelitis optica

Isobe N, Matsushita T, Yamasaki R, Ramagopalan S.V., Kawano Y, Nishimura Y, Ebers G.C., Kira J 2010

[学会発表] CSF angiotensin II and angiotensin-converting enzyme levels inanti-aquaporin-4 autoimmunity.

松下拓也 2010

[雑誌論文] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitis optica according to anti-aquaporin-4 antibody status.

Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, Masaki K, Yoshimura T, Yamasaki R, Ohyagi Y, Kira J 2010

[学会発表] Altered production of brain-derived neurotrophic factor by peripheral blood immune cells in multiple sclerosis.

Yoshimura S, Ochi H, Isobe N, Matsushita T, Motomura K, Minohara M, Kira J 2010

[学会発表] P-15 : Cytokine and T helper cell profiles in Multiple Sclerosis.

Doi H, Zong SY, Matsushita T, Isobe N, Yonekawa T, Masaki K, Kira J 2010

[学会発表] MS およびNMOにおける脳脊髄液サイトカインの解析およびIFNβ による影響.

土井光, 松下拓也, 立石貴久, 磯部紀子, 大八木保政, 吉良潤一 2010

[雑誌論文] CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity.

松下拓也, ら 2010

[学会発表] Extensive Aquaporin-4 Loss in Balo's Concentric Sclerosis: Anti-Aquaporin-4 (AQP4) Antibody-Independent Astrocytopathy in Balo's Concentric Sclerosis.

Kira J, Matsuoka T, Suzuki SO, Yonekawa T, Masaki K, Tabira T, Iwaki T, Wu XM, Matsushita T 2010

[学会発表] 中枢神経系におけるCLDND1の発現と脱髄疾患への関与.

真崎勝久, 三野原元澄, 米川智, 磯部紀子, 松下拓也, 吉良潤一 2010

[学会発表] アクアポリン4M1,M23 各イソフォームに対するNMO 及びMS 患者血清の反応性の検討

米川智, 真崎勝久, 磯部紀子, 松下拓也, 吉良潤一 2010

[学会発表] T cell reactivities to major myelin protein-derived peptides in anti-aquaporin-4 antibody-positive and -negative patients with multiple sclerosis.

Matsushita T, Masaki K, Minohara M, Isobe N, Kawano Y, Yamasaki R, Nishimura N, Kira J 2009

[雑誌論文] Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis.

Kihara Y, Matsushita T, Kita Y, Uematsu S, Akira S, Kira J, Ishii S, Shimizu T 2009

[雑誌論文] Frequency of chronic headaches in Japanese patients with multiple sclerosis : with special reference to opticospinal and conventional forms of multiple sclerosis

Doi H, Matsushita T, Isobe N, Ishizu T, Ohyagi Y, Kira J 2009

[雑誌論文] Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and -negative multiple sclerosis patients

Watanabe A, Matsushita T, Doi H, Matsuoka T, Shigetou H, Isobe N, Kawano Y, Tobimatsu S, Kira J 2009

[雑誌論文] Hypercomplementemia at relapse in patients with anti-aquaporin-4antibody

Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J 2009

[雑誌論文] Extensive vasogenic edema of anti-aquaporin-4 antibody-related brain lesions

Matsushita T, Isobe N, Matsuoka T, Ishizu T, Kawano Y, Yoshiura T, Ohyagi Y, Kira J 2009

[学会発表] Anti-AQP4 autoimmunity-related and -unrelated opticospinal multiple sclerosis in Japanese.

Matsushita T, Matsuoka T, Tanaka M, Shi N, Suzuki S, Iwaki T, Kira J 2009

[雑誌論文] Association of the HLA-DPB1*0501allele with anti-aquaporin-4 antibody positivity in Japanese patients with idiopathic central nervous system demyelinating disorders

Matsushita T, Matsuoka T, Isobe N, Kawamura Y, Minohara M, Shi N, Nishimura Y, Ochi H, Kira J 2009

[学会発表] Pathological heterogeneity and T cell participation in the neuromyelitis optica/opticospinal form of MS.

松下拓也 2009

[学会発表] Pathological heterogeneity and T cell participation in the neuromyelitis optica/opticospinal form of MS.

Matsushita T, Matsuoka T 2009

[雑誌論文] Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica.

Li W, Minohara M, Piao H, Matsushita T, Masaki K, Matsuoka T, Isobe N, Su JJ, Ohyagi Y, Kira J 2009

[雑誌論文] Extensive vasogenic edema of anti-aquaporin-4 antibody-related brain lesions.

松下拓也, ら 2009

[学会発表] 抗aquaporin-4(AQP4)抗体陽性例におけるT細胞内・脳脊髄液中サイトカインの特徴

松下拓也 2009

[学会発表] 多発性硬化症に合併する慢性頭痛患者の髄液中サイトカイン分析

土井光, 松下拓也, 立石貴久, 磯部紀子, 大八木保政, 吉良潤一 2009

[学会発表] The influence of HLA-DRB1 alleles on the susceptibility and resistance to multiple sclerosis with respect to the criteria of neuromyelitis optica.

Isobe N, Matsushita T, Yamasaki R, Ramagopalan S.V., Kawano Y, Nishimura Y, Ebers G.C., Kira J 2009

[学会発表] T cell reactivities to major myelin protein-derived peptides in anti-aquaporin-4 antibody-positive and -negative patients with multiple sclerosis

松下拓也 2009

[学会発表] Sjogren症候群と神経疾患

松下拓也 2009

[雑誌論文] Aquaporin-4 autoimmune syndrome and anti-aquaporin-4 antibody-negative opticospinal multiple sclerosis in Japanese.

松下拓也, ら 2009

[学会発表] Roles of cytokines/chemokines in multiple sclerosis

松下拓也 2009

[学会発表] Anti-AQP4 autoimmunity-related and -unrelated opticospinal multiple sclerosis in Japanese.

松下拓也 2009

[雑誌論文] Aquaporin-4 autoimmune syndrome and anti-aquaporin-4 antibody-negative opticospinal multiple sclerosis in Japanese

Matsushita T, Isobe N, Matsuoka T, Shi N, Kawano Y, Wu X-M, Yoshiura T, Nakao Y, Ishizu T, Kira J 2009

[学会発表] Anti-AQP4 autoimmunity-related and -unrelated opticospinal multiple sclerosis in Japanese.

松下拓也 2009