研究成果

[学会発表] Characterization of mercury binding proteins in the liver of northern fur seals (Callorhinus ursinus)

Agusa, T., Yasugi, S., Ikemoto, T., Kunito, T., Baba, N., Tanabe, S. and Iwata, H. 2014

[雑誌論文] Human exposure to arsenic from drinking water in Vietnam

Agusa, T., Trang, P. T. K., Lan, V. M., Anh, D. H., Tanabe, S., Viet, P. H. and Berg, M. 2014

[図書] 健康と環境の科学（川添禎浩　編）

石橋弘志，有薗幸司 2013

[学会発表] 有明海の河口域における残留性有機汚染物質の空間分布と分配

小林　淳，小森田智大，中島尚哉，石原文隆，伊牟田優希，梅原　亮，石橋弘志，有薗幸司，堤　裕昭，古賀　実 2013

[学会発表] PPCPsのエストロゲン様作用のin silicoスクリーニング

瀬原葉子，石橋弘志，石橋康弘，有薗幸司 2013

[学会発表] 有明海の河口域に棲息する水生生物への残留性有機汚染物質の蓄積解析

伊牟田優希，小林　淳，小森田智大，中島尚哉，石原史隆，梅原　亮，石橋弘志，有薗幸司，堤　裕昭，古賀　実 2013

[学会発表] Homology modeling and ligand docking simulations of avian AhRs to decipher the interspecies differences in responses to dioxins

Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. 2013

[図書] 健康・栄養科学シリーズ　食べ物と健康　食品の安全

石橋弘志，髙本亜希子 2013

[雑誌論文] Study of dietary phytoestrogens and estrogenic activity in pet animal diets

Nakashima, S., Ji, H., Ishitobi, S., Kawazoe, S., Koga, M., Shinohara, R., Ishibashi, H., Tominaga, N. and Arizono, K. 2013

[学会発表] Identification of aminio acid residues critical for ligand binding and transactivation in ecdysone receptor

Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. 2013

[学会発表] In vitro and in silico analyses to predict the effects of environmental chemicals through the mysid ecdysteroid receptor signaling pathway

Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. 2013

[学会発表] 海産魚類における残留性有機汚染物質の体内分布特性

石原史隆，小林　淳，小森田智大，中島尚哉，伊牟田優希，梅原　亮，石橋弘志，有薗幸司，堤　裕昭，古賀　実 2013

[学会発表] Transcriptomic analysis of the liver of Japanese medaka (Oryzias latipes) exposed to Kanechlor-500, BDE47 or PFOS

Ishibashi, H., Uchida, M., Hirano, M., Kobayashi, J., Komorita, T., Nakamura, H., Kagami, Y., Kusano, T., Ishibashi, Y. and Arizono, K. 2013

[学会発表] Isoform-specific transactivation and autoinduction of aryl hydrocarbon receptors by dioxins in the red seabream (Pagrus major)

Bak, S. M., Iida, M., Iwata H. and Kim, E. Y. 2013

[学会発表] TCDD 曝露したマダイ胚のトランスクリプトーム解析

飯田 緑, 藤井 聡, 内田雅也, 中村 浩, 鏡 良弘, Bak Su-Min, Kim Eun-Young, 島 康洋, 岩田久人 2013

[学会発表] In silico analysis of avian AHRs to decipher the molecular basis for interspecies differences in responses to dioxins

Hirano, M., Bak, S. M., Iwata, H. and Kim, E .Y. 2013

[学会発表] Isoform-specific responses of aryl hydrocarbon receptor to dioxins in red seabream (Pagrus major)

Bak, S. M., Kim, E. Y., Iida, M. and Iwata, H. 2013

[学会発表] Thyroid hormone-mediated effects of dioxins in wild Baikal seals (Pusa sibirica)

Iwata, H, Hirakawa, S., Eguchi, A., Imaeda, D., Kunisue, T., Kim, E. Y., Kannan, K., Petrov, E. A., Batoev, V. B. and Tanabe, S. 2013

[雑誌論文] Alternative in vitro approach for assessing AHR-mediated CYP1A induction by dioxins in wild cormorant (Phalacrocorax carbo) population

Thuruthippalli, L. M., Kubota, A. Kim, E. Y., Iwata, H 2013

[学会発表] In silico 解析による化学物質と核内受容体・シトクロムP450の相互作用の評価

岩田久人, 平野将司, Kim Eun-Young 2013

[学会発表] Identification of quantitative trait loci (QTL) associated with inorganic arsenic metabolism using recombinant inbred strains of mice

Agusa, T., Komori, H., Soga, Y., Nose, M., Mori, S., Kubota, R., Tanabe, S. and Iwata, H. 2013

[学会発表] ベトナム人におけるAS3MT遺伝子の発現量とSNPsの関係

阿草哲郎, 國頭 恭, Nguyen Minh Tue, Vi, T. M. Lan, Tu, B. Minh, Pham, T. K. Trang, 藤原純子, 竹下治男, 高橋 真, Pham, H. Viet, 田辺信介, 岩田久人 2013

[学会発表] Effect of aryl hydrocarbon receptor variants and hnRNPA2/B1 on dioxin-induced cyp1a1 transactivation in MRL/lpr and C3H/lpr

Cho, S. W., Suzuki, K. I., Miura, Y., Watanabe, M., Miyazaki, T., Nose, M., Iwata, H. and Kim, E. Y. 2013

[学会発表] In silico 解析による化学物質と核内受容体・シトクロムP450 の相互作用の評価

岩田久人、平野将司、Kim, Eun-Young 2013

[雑誌論文] Molecular and functional characterization of a novel aryl hydrocarbon receptor isoform, AHR1β in the chicken (Gallus gallus)

Lee, J. S., Iwabuchi, K., Nomaru, K., Nagahama, N., Kim, E. Y., Iwata, H 2013

[学会発表] Polychlorinated biphenyls and their hydroxylated metabolites (OH-PCBs) in the Baikal seals and implication from a toxicogenomic approach

Nomiyama, K., Eguchi, A., Hirakawa, S. Kanbara, C., Imaeda, D., Kim, E. Y., Iwata, H. and Tanabe, S. 2013

[学会発表] Effects of aryl hydrocarbon receptor and transcriptional co-factor(s) on transactivation in MRL/lpr and C3H/lpr mouse strains

Cho, S. W., Kim, E. Y., Suzuki, K., Miura, Y., Iwata, H., Miyazaki, T. and Nose, M. 2013

[雑誌論文] Sex differences in the accumulation of chlorinated dioxins in the cormorant (Phalacrocorax carbo) : implication of hepatic sequestration in the maternal transfer

Kubota, A., Yoneda, K., Tanabe, S., Iwata, H 2013

[学会発表] In vitro approach to predict AHR-mediated CYP1A induction by dioxins in cormorant population

Iwata, H., Thuruthippallil, L. M., Kubota, A. and Kim, E. Y. 2013

[学会発表] ホッキョクグマのシトクロムP450 1Aおよび2BによるPCBs代謝能力の評価

古池 幸, 平野将司, 鈴木賢一, Yoo Jean, 阿草哲郎, Thomas J. Evans, Kurunthachalam Kannan, 岩田久人 2013

[学会発表] Identification and functional characterization of a novel chicken aryl hydrocarbon receptor isoform, 2nd AHR1

Lee, J. S., Iwabuchi, K., Nomaru, K., Nagahama, N., Kim, E. Y. and Iwata, H. 2013

[学会発表] Identification of cytochrome P450 enzymes in phenobarbital-treated mouse liver microsomes using 2-DE and MALDI-TOF/TOF

Lauan, M. C., Suzuki, K., Agusa, T. and Iwata, H. 2013

[学会発表] バイカルアザラシの微量元素蓄積とその応答遺伝子の探索

阿草哲郎，平川周作，渡邉　泉，池本徳孝，宇高真行，金　恩英，Evgeny, A. Petrov, Valeriy, B. Batoev, 田辺信介，岩田久人 2013

[学会発表] Functional characterization of aryl hydrocarbon receptor from the polar bear (Ursus maritimus)

Hwang, J. H., Jeong, L. R., Kannan, K., Evans, T. J., Iwata, H. and Kim, E. Y. 2013

[学会発表] 組換え近交系マウスを用いたヒ素感受性遺伝子座の同定

阿草哲郎，小森浩章，曽我美子，宮崎龍彦，能勢眞人，森　士朗，久保田領志，田辺信介，岩田久人 2013

[学会発表] Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor α by brominated flame retardants

Ishibashi, H. 2012

[学会発表] Binding of perfluorochemicals to PPARα: toward establishing the linkage between the initiating event and its downstream signaling

Ishibashi, H. 2012

[学会発表] 鳥類の環境毒性学：AHRシグナル伝達系の特徴とダイオキシン類のリスク評価

岩田久人 2012

[学会発表] In vitro transactivation potencies of cormorant AHR1 and AHR2 by dioxin-like chemicals and their application to risk assessment of the wild population

Iwata, H. 2012

[学会発表] 鳥類の環境毒性学 : AHRシグナル伝達系の特徴とダイオキシン類のリスク評価

岩田久人 2012

[学会発表] Development of ecotoxicological tools for the assessment of susceptibility and risk

Iwata, H 2012

[学会発表] 組換え近交系マウスにおけるダイオキシン感受性の系統差：AhR非依存的規程因子の探索(2)

岩田久人 2012

[学会発表] In vitro transactivation of avian AHR1 and AHR2 by dioxins to assess the species-specific sensitivity and CYP1A induction in the population-level

Iwata, H. 2012

[学会発表] Direct binding affinities of perfluoroalkyl carboxylates and sulfonates to the Baikal seal and human peroxisome proliferator-activated receptor α

Ishibashi, H. 2011

[学会発表] Transactivation potencies of the Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and sulfonates: estimation of PFOA induction equivalency factors

Ishibashi, H. 2011

[学会発表] In vitro approaches for assessing the risk of toxic contaminants in wildlife

Iwata, H. 2011

[学会発表] Molecular and functional characterization of aryl hydrocarbon receptor repressor (AHRR) from the chicken (Gallus gallus).

Iwata, H., Lee, J.S., Kim, E.Y., Nomaru, K. 2011

[学会発表] Association of arsenic exposure and genetic polymorphisms with arsenic metabolism in a Vietnamese population.

Agusa, T., Kunito, T., Fujiwara, J., Takeshita, T.B., Min, P.K., Viet, P.H., Tanabe, S., Iwata, H. 2011

[雑誌論文] Cytochrome P450 CYP2 genes in the common cormorant : evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expression

Kubota, A., Stegeman, J. J., Goldstone, J. V., Nelson, D. R., Kim, E. Y., Tanabe, S., Iwata, H 2011

[図書] 環境毒性学　7. 環境毒性学の未来

岩田久人 2011

[図書] 環境毒性学 7 環境毒性学の未来

岩田久人 2011

[雑誌論文] 8-Hydroxy-2'-deoxyguanosine and arsenic compounds in urine and serum of a 4-year-old child suffering from acute promyelocytic leukemia during treatment with arsenic trioxide.

Fujihara, J., Hasegawa, M., Kanai, R., Agusa, T., Iwata, H., Tanabe, S., Yasuda, T., Yamaguchi, S., Takeshita, H. 2011

[学会発表] Advanced alternative approaches to wildlife testing for toxicological research: A case study of the effects of perfluorochemicals on Baikal seals

Iwata, H. 2011

[学会発表] 2,3,7,8-tetrachlorodibenzo-p-dioxin responsive transcripts in avian embryonic liver, identified by large-scale differential display system with vertebrate-common degenerate oligonucleotide primers.

Teraoka, H., Ito, S., Ukai, N., Kim, E.Y., Iwata, H., Kitazawa, T., Hiraga, T., Endoh, D. 2011

[学会発表] In vitro approaches for assessing the risk of toxic contaminants in wildlife

Iwata, H. and Kim, E. Y 2011

[雑誌論文] Molecular and functional characterization of aryl hydrocarbon receptor nuclear translocator 1 (ARNT1) and ARNT2 in chicken (Gallus gallus)

Lee, J. S., Kim, E. Y., Iwabuchi, K., Iwata, H 2011

[図書] 3.6.バイオマーカー, 環境毒性学, 渡邉 泉・久野勝治編

岩田久人 2011

[図書] 環境毒性学3.6バイオマーカー

岩田久人 2011

[学会発表] Molecular and functional characterization of Baikal seal AHR-CYP1 signaling pathway

Iwata, H. 2011

[学会発表] ベトナム人におけるヒ素代謝能の個人差:ヒ素曝露レベルと代謝遺伝子多型の影響.

阿草哲郎・岩田久人・國頭恭・藤原純子・Minh,T.B.・Trang, P.T.K.・Viet, P.H.・竹下治男・田辺信介 2011

[学会発表] 野生生物のシトクロム P450 と環境汚染物質

岩田久人 2011

[雑誌論文] Molecular and functional characterization of aryl hydrocarbon receptor repressor from the chicken (Gallus gallus) : interspecies similarities and differences

Lee, J. S., Kim, E. Y., Nomaru, K., Iwata, H 2011

[図書] 環境毒性学　3.6. バイオマーカー

岩田久人 2011

[雑誌論文] Intake and excretion of arsenicals in green (Chelonia mydas) and hawksbill turtles(Eretmochelys imbricata).

Agusa, T., Takagi, K., Miller, T.W., Kubota, R., Anan, Y., Iwata, H., Tanabe, S. 2011

[雑誌論文] Molecular and functional characterization of aryl hydrocarbon receptor repressor from the chicken (Gallus gallus) : interspecies similarities and differences.

Lee, J.S., Kim, E.Y., Nomaru, K., Iwata, H. 2011

[雑誌論文] Evaluation of relative potencies for in vitro transactivation of the Baikal seal aryl hydrocarbon receptor by dioxin-like compounds.

Kim, E.Y., Suda, T., Tanabe, S., Batoev, V.B., Petrov, E.A., Iwata, H. 2011

[雑誌論文] Human FAT1 cadherin controls cell migration and invasion of oral squamous cell carcinoma through the localization of beta-catenin

Nishikawa, Y. 2011

[学会発表] Transcriptional activities of Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor a by perfluoroalkyl carboxylates and perfluoroalkyl sulfonates.

Ishibashi, H., Kim, E.Y., Iwata, H. 2010

[学会発表] Transactivation potencies of the Baikal Seal (Pusa sibirica) peroxisome proliferator-activated receptor a by perfluoroalkyl carboxylates and sulfonates : Estimation of PFOA induction equivalency factors.

Ishibashi, H., Kim, E.Y., Iwata, H. 2010

[雑誌論文] Contamination of pharmaceutical and personal care products in sewage treatment plants and surface waters in South Korea and their removal during activated sludge treatment.

Kim, J.W., Ishibashi, H., Hirano, M., Jang, H.S., Kim, J.G., Takao, Y., Ichikawa, N., Shinohara, R., Arizono, K. 2010

[学会発表] Transactivation potencies of Baikal seal (Pusa sibirica) peroxisome proliferator-activated receptor a by perfluoroalkyl carboxylates and perfluoroalkyl sulfonates.

Ishibashi, H., Kim, E.Y., Iwata, H. 2010

[学会発表] Screening of environmental chemicals using a surface plasmon resonance(SPR)biosensor in combination with constitutive androstane receptor(CAR).

Pham, T.D., Ishibashi, H., Kim, E.Y., Iwata, H. 2010

[雑誌論文] Decolorization and estrogenic activity of colored livestock watewater by electrolysis system.

Kai, H., Ishibashi, Y., Mori, T., Ishibashi, H., Kawaguchi, T., Ohwaki, H., Arizono, K., Takemasa, T. 2010

[学会発表] Effects of endogenous and xenobiotic compounds on DNA binding and transactivation of the crustacean ecdysteroid receptor.

Hirano, M., Ishibashi, H., Kim, E.Y., Arizono, K., Iwata, H. 2010

[図書] Development of an in vitro reporter gene assay for screening the ecdysone receptor agonists in mysid crustacean, Interdisciplinary Studies on Environmental Chemistry Vol.4, Environmental Specimen Bank : Exploring Possibility of Setting-up ESBs in Developing Countries

Hirano, M., Ishibashi, H., Kim, E.Y., Arizono, K., Iwata, H. 2010

[雑誌論文] Decolorization and estrogenic activity of colored livestock wastewater by electrolysis system

Kai, H., Ishibashi, Y., Mori, T., Ishibashi, H., Kawaguchi, T., Ohwaki, H., Arizono, K., Takemasa, T. 2010

[学会発表] Functional analyses of the mysid ecdysteroid receptor : molecular cloning, DNA binding ability and ligand-induced transactivation.

Hirano, M., Ishibashi, H., Kim, E., Arizono, K., Iwata, H. 2010

[学会発表] ふっ素テロマーアルコールがヒメダカ再生産に及ぼす影響

山内良子・石橋弘志・内田雅也・孫〓富・平野将司・金俊佑・冨永伸明・有薗幸司 2010

[学会発表] Effects of endogenous and xenobiotic ligands on DNA binding and transactivation of the mysid ecdysteroid receptor.

Hirano, M., Ishibashi, H., Kim, E.Y., Arizono, K., Iwata, H. 2010

[雑誌論文] ダイエタリーサプリメント使用される大豆抽出物とエチニルエストラジオールの複合エストロゲン活性

川添禎浩・那智和奈・石橋弘志・小原智未・有薗幸司・橋本香織・北条康司・鈴木隆 2010

[図書] Molecular characterization of peroxisome proliferator-activated receptor isoforms from the Baikal seal (Pusa sibirica), Interdisciplinary Studies on Environmental Chemistry Vol.4, Environmental Specimen Bank : Exploring Possibility of Setting-up ESBs in Developing Countries

Ishibashi, H, Kim, E.Y., Tanabe, S., Iwata, H. 2010

[学会発表] Transactivation potencies of the Baikal seal (Pusa sibirica) pregnane X receptor by persistent organic pollutants.

Pham, T.T.L., Ishibashi, H., Kadota, M., Kim, E.Y., Iwata H. 2010

[学会発表] Functional characterization of cytochrome P450 1A1, 1A2 and 1B1 from the Baikal seal(Pusa sibirica).

Yamaguchi, K., Kim, E.Y., Kubota, A.,Iwata, H. 2010

[図書] Cytochrome P450 family 1 genes in Xenopus tropicalis, Interdisciplinary Studies on Environmental Chemistry Vol.4, Environmental Specimen Bank : Exploring Possibility of Setting-up ESBs in Developing Countries

Suzuki, K.T., Iwata, H. 2010

[学会発表] Arsenic, manganese and barium contamination in groundwater and human in Vietnam

Agusa, T., Inoue, S., Kunito, T., Minh, T.B., Tu, N.P.C., Ha, N.N., Kim Trang, P.T., Iwata, H., Tuyen, B.C., Viet, P.H., Tanabe, S. 2010

[学会発表] Cytochrome P450 CYP2 genes in the common cormorant : evolutionary relationships with diapsid CYP2 clan sequences and chemical effects on their expression.

Kubota, A., Stegeman, J., Goldstone, J., Nelson, D., Kim, E.Y., Tanabe, S.,Iwata, H. 2010

[雑誌論文] Effects of in ovo exposure to 2,3,7,8-tetrachlorodibenzo-p-doxin on hepatic AHR/ARNT CYP1A signaling pathways in common cormorants (Phalacrocoraxcarbo).

Iwata, H., Nagahama, N., Kim, E.Y., Watanabe, M.X., Sudo, A. 2010

[学会発表] Studies on cytochrome P450 expression and function in wildlife.

Iwata, H. 2010

[雑誌論文] Hepatic CYP1A introduction by chlorinated dioxins and related compounds in the endangered black-footed albatross from the North Pacific.

Kubota, A., Watanabe, M., Kunisue, T., Kim, E.Y., Tanabe, S., Iwata, H. 2010

[雑誌論文] Effects of in ovo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic AHR/ARNTCYP1A signaling pathways in common cormorants (Phalacrocorax carbo)

Iwata, H., Nagahama, N., Kim, E. Y., Watanabe, M. X., Sudo, A 2010

[学会発表] Regulation and catalytic function of avian CYP1A: Interspecies similarities and differences.

Iwata, H., Kim, E.Y., Lee, J.S., Kubota, A. 2010

[図書] Interindividual variation in arsenic metabolism in a Vietnamese population : association with 17 single nucleotide polymorphisms in AS3MT, Interdisciplinary Studies on Environmental Chemistry vol.3, Bioloical Responses to Contaminants : from Molecular to Community Level

Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T.B., Trang, P.T.K., Viet, P.H., Tanabe, S. 2010

[雑誌論文] Dioxin-like and perfluorinated compounds in pigs in an Indian open waste dumping site : toxicokinetics and effects on hepatic cytochrome P450 and blood plasma hormones

Watanabe, M.X., Kunisue, T., Tao, L., Kannan, K., Subramanian, An., Tanabe, S., Iwata, H. 2010

[図書] Risk assessment of dioxins in wild birds by the combination of contamination level and species-specific response of aryl hydrocarbon receptor, Interdisciplinary Studies on Environmental Chemistry vol.3, Biological Responses to Contaminants : from Molecular to Community Level

Iwata, H., Kim, E.Y. 2010

[学会発表] Characterization of the AHR/ARNT/AHRR-CYP1A signaling pathway in avian species.

Iwata, H., Lee, J.S., Kim, E.Y. 2010

[学会発表] ベトナムのヒ素汚染地域住民におけるヒ素代謝に関与する要因

阿草哲郎・岩田久人・藤原純子・國頭恭・竹下治男・Minh, T.B.・Trang P.T.K.・Viet, P.H.・田辺信介 2010

[図書] Toxic effects of 2,3,7,8-tetrachlorodibenzo p-dioxin (TCDD) on peripheral nervous system of developing red seabream (Pagrus major) embryos, Interdisciplinary Studies on Environmental Chemistry Vol.4, Environmental Specimen Bank : Exploring Possibility of Setting-up ESBs in Developing Countries

Iida, M., Kim, E.Y., Murakami, Y., Shima, Y., Iwata, H. 2010

[図書] Methylation of inorganic arsenic and genetic polymorphisms in arsenic (+III oxidation state)methyltransferase in a Vietnamese population, Arsenic in Geosphere and Human Diseases

Agusa, T., Fujihara, J., Takeshita, H., Tanabe, S., Iwata, H., Kunito, T., Minh, T.B., Trang, P.T.K., Viet, P.H. 2010

[雑誌論文] A microarray data analysis method to evaluate the impact of contaminants on wild animals.

Nakayama, K., Handoh, I.C., Kitamura, S., Kim, E.Y., Iwata, H.,Tanabe, S. 2010

[学会発表] Accumulation of trace elements in harp seals (Phoca groenlandica) from Pangnirtung in Baffin Island, Canada.

Agusa, T., Nomura, K., Kunito, T., Anan, Y., Iwata, H., Tanabe, S. 2010

[学会発表] Chemical impacts on aquatic birds and mammals : xenobiotic receptor-based risk assessment.

Iwata, H., Kim, E.Y. 2010

[雑誌論文] Exposure, metabolism, and health effects of arsenic in residents from arsenic-contaminated groundwater areas of Vietnam and Cambodia : A review.

Agusa, T., Kunoto, T., Kubota, R., Inoue, S., Fujihara, J., Minh, T.B., Ha, N.N., Tu, N.P.C., Trang, P.T.K., Chamnan, C., Takeshita, H., Iwata, H., Tuyen, B.C., Viet, P.H., Tana, T.S., Tanabe, S. 2010

[学会発表] Chemical impacts on aquatic birds and mammals : xenobiotic receptor-based risk assessment

Iwata, H. and Kim, E. Y 2010

[雑誌論文] Dioxin-like and perfluorinated compounds in pigs in an Indian open waste dumping site : toxicokinetics and effects on hepatic cytochrome P450 and blood plasma hormones

Watanabe, M. X., Kunisue, T., Tao, L., Kannan, K., Subramanian, An., Tanabe, S., Iwata, H 2010

[雑誌論文] ベトナム人におけるAS3MT遺伝子多型とヒ素代謝能の関係

阿草哲郎・藤原純子・竹下治男・田辺信介・岩田久人・國頭恭 2010

[図書] Risk assessment of dioxins in wild birds by the combination of contamination level and species-specific response of aryl hydrocarbon receptor, Proceeding Book "Interdisciplinary Studies on Environmental Chemistry, Vol. 3",

岩田久人, 金恩英 2010

[学会発表] Risk assessment of dioxins and related compounds in the black-footed albatross : Application of an in vitro approach.

Thuruthippallil L.M., Kim, E.Y.,Iwata, H. 2010

[学会発表] Methylation of inorganic arsenic and genetic polymorphisms in arsenic (+III oxidation state) methyltransferase in a Vietnamese population.

Agusa, T., Fujihara, J., Takeshita, H., Tanabe, S., Iwata, H., Kunito, T., Minh, T.B., Trang, P.T.K., Viet, P.H. 2010

[学会発表] Identification and characterization of CYP1 genes in Xenopus laevis and Xenopus tropicalis.

Suzuki, K.T., Iwata, H. 2010

[雑誌論文] Hepatic CYP1A introduction by chlorinated dioxins and related compounds in the endangered black-footed albatross from the North Pacific

Kubota, A., Watanabe, M., Kunisue, T., Kim, E. Y., Tanabe, S., Iwata, H 2010

[学会発表] Transcriptional regulation of CYP1A genes in amphibians.

Suzuki, T.K.,Iwata, H. 2010

[雑誌論文] Dioxin-like and perfluorinated compounds in pigs in an Indian open waste dumping site : toxicokinetics and effects on hepatic cytochrome P450 and blood plasma hormones.

Watanabe, M.X., Kunisue, T., Tao, L., Kannan, K., Subramanian, An., Tanabe, S., Iwata, H. 2010

[学会発表] ベトナム人のヒ素代謝プロファイルとGST遺伝子多型の関係:ヒ素暴露レベルの影響

阿草哲郎・岩田久人・藤原純子・國頭恭・Minh, T.B.・Trang, P.T.K.・Vet, P.H.・竹下治男・田辺信介 2010

[学会発表] Characterization of CYP1 genes in Xenopus laevis and Xenopus tropicalis.

Suzuki, K., Iwata, H. 2010

[学会発表] 芳香族炭化水素受容体(AhR)の分子生物学的解析による鳥類のダイオキシン類感受性評価

藤澤希望・池中良徳・山本秀明・金恩英・李鎮善・岩田久人・石塚真由美 2010

[学会発表] Moleculaz cloning of the ecdysone receptor from a mysid crustacean(Americamysis bahia)and development of an in vitro reporter gene assay to detect the receptor-mediated responses by chemicals

Hirano, M., Ishibashi, H., Kim, E.Y., Arizono, K., Iwata, H. 2009

[学会発表] 線虫 C. elegans を用いた食品中機能性成分の抗酸化作用評価

山元涼子・井口綾子・内匠正太・上田清佳・石橋弘志・冨永伸明・有薗幸司 2009

[雑誌論文] Expression analysis of estrogen-responsive genes vitellogenin 1 and 2 in liver of male medaka(Oryzias latipes)exposed to selective ligands of estrogen receptor subtypes

Yamaguchi, A., Ishibashi, H., Kohra, S., Arizono, K., Kato, K., Nakahama, T., Kanno, Y., Inouye, Y., Tominaga, N. 2009

[学会発表] Development of an in vitro reporter gene assay for screening the ecdysone receptor agonists in mysid crustacean, Americamysis bahia

Hirano, M., Ishibashi, H., Kim, E.Y., Arizono, K., Iwata, H. 2009

[学会発表] Molecular characterization of peroxisome proliferator-activated receptor isoforms from the Baikal seal(Pusa sibirica)

Ishibashi, H., Kim, E.Y., Tanabe, S., Iwata, H. 2009

[雑誌論文] Effects of nonylphenol on growth and 20-hydroxyecdysone levels in mysid crustacean, Americamysis bahia

Hirano, M., Ishibashi, H., Kim, J.W., Matsumura, N., Arizono, K. 2009

[学会発表] ERα/ERβ選択性リガンドを用いたメダカvtg1/2の発現誘導解析

山口明美・石橋弘志・高良真也・有園幸司・加藤恵介・中浜隆之・菅野雄一朗・井上義雄・冨永伸明 2009

[学会発表] A preliminary study on chemical ligand screening of the constitutive androstane receptor(CAR)using a surface plasmon resonance array system

Dau, P.T., Ishibashi, H., Kim, E.Y., Iwata H. 2009

[学会発表] 線虫DNAマイクロアレイによるリチウムの影響評価

井口綾子・内匠正太・山元涼子・石橋弘志・冨永伸明・有薗幸司. 2009

[学会発表] メダカ繁殖試験によるフッ素テロマーアルコールの影響評価

山内良子・石橋弘志・内田雅也・孫〓富・竹元望・竹本直道・金俊佑・平野将司・有薗幸司 2009

[学会発表] Characterization of ecdysone receptor and ultraspiracle mRNA through molting period in mysid crustacean

Hirano, M., Ishibashi, H., Yamauchi, R., Kim, J.W., Arizono, K. 2009

[学会発表] Molecular characterization of peroxisome proliferators-activated receptor β/σ from the Baikal seal(Pusa sibirica)

Ishibashi, H., Kim, E.Y., Tanabe, S., Iwata, H. 2009

[学会発表] Transcriptional modulation of estrogen-responsive genes in male medaka(Oryzias latipes)after exposure to synthetic polycyclic musks

Ishibashi, H., Yamauchi, R., Kim, J.W., Hirano, M., Mori, T., Tominaga, N., Arizono, K. 2009

[学会発表] メダカDNAマイクロアレイを用いたエストロゲン様物質により変動する遺伝子群の網羅的解析

内田雅也・石橋弘志・平野将司・金俊佑・冨永伸明・山内良子・有薗幸司 2009

[学会発表] 有機フッ素化合物によるヒメダカ肝臓中CYP3As発現誘導

山内良子・石橋弘志・平野将司・金俊佑・高尾雄二・有薗幸司. 2009

[学会発表] 環境化学物質に曝露したメダカにおけるDNAマイクロアレイを用いた遺伝子発現解析 -第1報-

竹元望・石橋弘志・平野将司・金俊佑・山内良子・孫〓富・内田雅也・有菌幸司 2009

[雑誌論文] Occurrence of pharmaceutical and personal care products(PPCPs)in surface water from Mankyung River, South Korea

Kim, J.W., Jang, H.S., Kim, J.G., Ishibashi, H., Hirano, M., Nasu, K., Ichikawa, N., Takao, Y., Shinohara, R., Arizono, K. 2009

[雑誌論文] Acute toxicity of pharmaceutical and personal care products on freshwater crustacean(Thamnocephalus platyurus)and fish(Oryzias latipes)

Kim, J.W., Ishibashi, H., Yamauchi, R., Ichikawa, N., Takao, Y., Hirano, M., Koga, M., Arizono, K. 2009

[学会発表] Cellular localization of the AHR isoforms(AHR1 and AHR2)from avian species

Nomaru, K., Kim, E.Y., Inoue, N., Yasui, T., Iwata, H. 2009

[学会発表] Identification and expression profile of CYP1-4 genes in Xenopus laevis

Suzuki, K., Iwata, H. 2009

[学会発表] ベトナムのヒ素汚染地域住民におけるAS3MT遺伝子多型とヒ素代謝の関係

阿草哲郎・岩田久人・藤原純子・國頭恭・Minh, T.B.・Kim Trang, P.T.・Viet, P.H.・竹下治男・田辺信介 2009

[学会発表] 環境汚染物質による野生生物のリスクを評価するための科学的方法

岩田久人・金恩英 2009

[雑誌論文] Genetic polymorphisms in glutathione S-transferase(GST)superfamily and arsenic metabolism in residents of the Red River Delta, Vietnam

Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T.B., Trnag, P.T., Viet, P.H., Tanabe, S. 2009

[学会発表] Characterization of aryl hydrocarbon receptor-cytochrome P450 1A signaling pathway in wildlife

Iwata, H, Kim, E.Y. 2009

[学会発表] ベトナム人におけるGSTスーパーファミリーの遺伝子多型と尿中ヒ素化合物プロファイルの関係

阿草哲郎・岩田久人・藤原純子・國頭恭・竹下治男・Minh, T.B.・Kim Trang, P.T.・Viet, P.H. 2009

[学会発表] Disruption of aryl hydrocarbon receptor-cytochrome P450 1A signaling pathway by dioxin-like chemicals in wildlife

Iwata, H, Kim, E.Y. 2009

[雑誌論文] Dioxin activation of CYP1A5 promoter/enhancer regions from two avian species, common cormorant(Phalacrocorax carbo)and chicken(Gallus gallus): Association with aryl hydrocarbon receptor 1 and 2 isoforms

Lee, J.S., Kim, E.Y., Iwata, H. 2009

[図書] 第5章生物反応を利用して化学物質汚染の危険性を検知する, 分子でよむ環境汚染, 鈴木聡編著

岩田久人・金 恩英 2009

[雑誌論文] Alkoxyresorufin(methoxy-, ethoxy-, pentoxy- and benzyloxyresorufin)O-dealkylase activities by in vitro-expressed cytochrome P450 1A4 and 1A5 from common cormorant(Phalacrocorax carbo)

Kubota, A., Kim, E.Y., Iwata, H. 2009

[雑誌論文] Alkoxyresorufin (methoxy-, ethoxy-, pentoxy- and benzyloxyresorufin) O-dealkylase activities by in vitro-expressed cytochrome P450 1A4 and 1A5 from common cormorant (Phalacrocorax carbo)

Kubota, A., Kim, E. Y., Iwata, H 2009

[雑誌論文] Human exposure to arsenic from groundwater in the red river and Mekong river deltas in Vietnam

Agusa, T., Inoue, S., Kunito, T., Minh, T.B., Ha, N.N., Tu, N.P.C., Kim Trang, P.T., Iwata, H., Viet, P.H., Tuyen, B.C., Tanabe, S. 2009

[学会発表] Quantitative assessment of the AHR-CYP1A signaling cascase in TCDD-treated avian embryos

Iwata, H., Nagahama, N., Watanabe, M., Kim, E.Y. 2009

[雑誌論文] Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants

Sakai, H., Kim, E.Y., Petrov, E.A., Tanabe, S., Iwata, H. 2009

[学会発表] Effects of TCDD on the AHR-CYP1A signaling cascade in avian developing embryos

Iwata, H., Nagahama, N., Watanabe, X.M., Kim, E.Y. 2009

[学会発表] Identification and characterization of cytochrome P450 and xenobiotics receptor genes in amphibians, Xenopus laevis and Xenopus tropicalis

Suzuki, K., Iwata, H. 2009

[学会発表] Intracellular localization of the AHR2 isoform from avian species

Nomaru, K., Kim, E.Y., Inoue, N., Yasui, T., Iwata, H. 2009

[学会発表] ベトナムにおけるAS3MT遺伝子多型とヒ素代謝能の関係

阿草哲郎・岩田久人・藤原純子・國頭恭・Minh, T.B.・Kim Trang, P.T.・Viet, P.H.・竹下治男・田辺信介 2009

[図書] 分子でよむ環境汚染(鈴木聡編)第5章 生物反応を利用して化学物質汚染の危険性を検知する

岩田久人・金恩英 2009

[学会発表] Functional analysis of the aryl hydrocarbon receptor repressor from chicken

Lee, J.S., Kim, E.Y., Iwata, H. 2009

[雑誌論文] Effects of co-exposure to 2,3,7,8-tetrachlorodihenzo-p-dioxin and perfluorooctane sulfonate or perfluorooctanoic acid on expression of cytochrome P450 isoforms in chicken(Gallus gallus)embryo hepatocyte cultures

Watanabe, M.X., Jones, S.P., Iwata, H., Kim, E.Y., Kennedy, S.W. 2009

[学会発表] 半網羅的ディファレンシャル・ディスプレイ法システムの構築

寺岡宏樹・池田晴喜・伊藤知子・鵜飼典佳・白石順也・金恩英・岩田久人・遠藤大二・平賀武夫 2009

[学会発表] ベトナム人のヒ素曝露とその代謝遺伝子多型

阿草哲郎・岩田久人・藤原純子・國頭恭・Minh, T.B.・Kim Trang, P.T.・Vie, P.H.・竹下治男・田辺信介 2009

[学会発表] Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on peripheral nervous system in developing red seabream(Pugrus major)embryos

Iida, M., Kim, E.Y., Murakami, Y., Shima, Y., Iwata, H. 2009

[雑誌論文] 8-hydroxy-2'-deoxyguanosine(8-OHdG)as a possible marker of arsenic poisoning : A clinical case study on the relationship between concentrations of 8-OHdG and each arsenic compound in urine of an acute promyelocytic leukemia patient being treated with arsenic trioxide

Fujihara, J., Agusa, T., Tanaka, J., Fujii, Y., Moritani, T., Hasegawa, M., Iwata, H., Tanabe, S., Takeshita, H. 2009

[学会発表] CYP1A transactivation potencies of the black-footed albatross AhR1 and and AhR2 by dioxins and risk assessment in the North Pacific population

Thuruthippallil, L.M., Kim, E.Y., Iwata, H. 2009

[学会発表] Association of inorganic arsenic metabolism with genetic polymorphisms of GST isoforms in North Vietnamese populations : Utilization of stored samples in the environmental specimen bank of Ehime University

Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T.B., Kim Trang, P.T., Viet, P.H., Tanabe, S. 2009

[学会発表] Interindividual variation in arsenic metabolism in a Vietnamese population : association with single nucleotide polymorphisms in AS3MT

Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T.B., Kim, P.T., Viet, P.H., Tanabe, S. 2009

[学会発表] Effects of dioxin-like and perfluorinated compounds on hepatic cytochrome P450 and plasma hormones in pigs from an indian open waste dumping site

Watanabe, X.M., Kunisue, T., Tao, L., Kannan, K., Subramanian, A., Tanabe, S., Iwata, H. 2009

[学会発表] Catalytic function of in vitro-expressed Baikal seal CYP1A1

Yamaguchi, K., Kim, E.Y., Iwata, H. 2009

[学会発表] Functional characterization of in vitro-expressed cytochrome P450 1A1, 1A2, and 1B1 from Baikal seal(Pusa sibirica)

Yamaguchi, K., Kim, E.Y., Iwata H. 2009

[学会発表] Risk Assessment of dioxins in the North Pacific black-footed albatross based on CYP1A transactivation potencies of the aryl hydrocarbon receptor 1 and 2(AhR1 and AhR2)

Thuruthippallil L.M., Kim, E.Y., Iwata, H. 2009

[雑誌論文] Genetic polymorphisms in AS3MT and arsenic metabolism in residents of the red river delta, Vietnam

Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T.B., Trang, P.T., Viet, P.H., Tanabe, S. 2009

[雑誌論文] Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants

Sakai, H., Kim, E. Y., Petrov, E. A., Tanabe, S., Iwata, H 2009

[雑誌論文] Accumulation features and temporal trends of PCDDs, PCDFs and PCBs in Baikal seals(Pusa sibirica)

Imaeda, D., Kunisue, T., Ochi, Y., Iwata, H., Tsydenova, O., Takahashi, S., Amano, M., Petrov, E.A., Batoev, V.B., Tanabe, S. 2009

[学会発表] Characterization of aryl hydrocarbon receptor in avian species

Fujisawa, N., Tanaka, K., Yamamoto, H., Ikenaka, Y., Kim, E.Y., Lee, J.S., Iwata, H., Ishizuka, M. 2009

[学会発表] Morphological changes in peripheral nervous system by TCDD in developing red seabream(Pagrus major)embryos

Iida, M., Kim, E.Y., Murakami, Y., Shima, Y., Iwata, H. 2009

[学会発表] Functional characterization of cytochrome P450 1A1, 1A2 and 1B1 from the Baikal seal(Pusa sibirica)heterologously expressed in yeast cells

Yamaguchi, K., Kim, E.Y., Kubota, A., Iwata, H. 2009

[学会発表] Functional characterization of AHR isoforms, AHR1, AHR2 and AHRR in avian species

Kim, E.Y., Lee, J.S., Inoue, N., Yasui, T., Iwata, H. 2009

[学会発表] ニワトリ新規AHR1アイソフォーム(2^<nd> AHR1)の機能解析

岩渕康平・金恩英・李鎮善・安井知子・岩田久人 2009

[学会発表] Quantitative analyses of AHR-CYP1A signaling in avian developing embryos

Iwata, H., Nagahama, N., Watanabe, M., Kim, E.Y. 2009

[雑誌論文] Relationship of urinary arsenic metabolites to intake estimates in residents of the Red river delta, Vietnam

Agusa, T., Kunito, T., Minh, T.B., Kim Trang, P.T., Iwata, H., Viet, P.H., Tanabe, S. 2009

[学会発表] CYP1A transactivation potencies of aryl hydrocarbon receptor 1 and 2(AHR1 and AHR2)from black-footed albatross by dioxin-like congeners

Thuruthippallil, L.M., Kim, E.Y., Iwata, H. 2009

[雑誌論文] Dioxin activation of CYP1A5 promoter/ enhancer regions from two avian species, common cormorant (Phalacrocorax carbo) and chicken (Gallus gallus) : association with aryl hydrocarbon receptor 1 and 2 isoforms

Lee, J. S., Kim, E. Y., Iwata, H 2009

[学会発表] Arsenic exposure and susceptibility in Vietnamese

Agusa, T., Kunito, T., Inoue, S., Minh, T. B., Tue, N. M., Ha, N. N., Tu, N. P C., Trang, P. T. K., Fujihara, J., Takeshita, H., Takahashi, S. Tuyen, B. C., Viet, P. H., Iwata, H. and Tanabe, S.

[学会発表] Proteomic analysis of liver microsomes in X. tropicalis

Suzuki, K. I., Nakano, M., Watabe, M., Fukuta, Y. and Iwata, H.

[学会発表] 無尾両生類のメタモルフォーゼにおける肝臓代謝酵素群の変化

鈴木賢一，中の三弥子，Daniel, R. Buchholz， 岩田久人，柏木啓子，山本　卓，柏木昭彦