トップ研究者を探す神経インターフェイス技法にもとづく重症心不全治療法の開発

神経インターフェイス技法にもとづく重症心不全治療法の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-20300177
研究種目 基盤研究(B)
研究分野 総合・新領域系
総合領域
人間医工学
医用システム
研究機関 高知大学
代表研究者 佐藤 隆幸
連携研究者 山崎 文靖
連携研究者 柿沼 由彦
連携研究者 有川 幹彦
連携研究者 鄭 燦
連携研究者 半田 武巳
連携研究者 野口 達哉
研究期間 開始年月日 2008/4/1
研究期間 終了年度 2010
研究ステータス 完了 (2010/4/1)
配分額(合計) 18,070,000 (直接経費 :13,900,000、間接経費 :4,170,000)
配分額(履歴) 2010年度:4,550,000 (直接経費 :3,500,000、間接経費 :1,050,000)
2009年度:6,630,000 (直接経費 :5,100,000、間接経費 :1,530,000)
2008年度:6,890,000 (直接経費 :5,300,000、間接経費 :1,590,000)
キーワード 循環器・高血圧
トランスレーショナルリサーチ
神経インターフェース
トレンスレーショナルリサーチ

研究成果

[雑誌論文] Effects of various doses of aspirin on platelet activity and endothelial function.

Furuno T, Yamasaki F, Yokoyama T, Sato K, Sato T, Doi Y, Sugiura T. 2011

[雑誌論文] Feasibility of ICG fluorescence-guided sentinel node biopsy in animal models using the HyperEye Medical System.

Yamauchi K, Nagafuji H, Nakamura T, Sato T, Kohno N 2011

[雑誌論文] Effects of various doses of aspirin on platelet activity and endothelial function.

Furuno T, Yamasaki F, Yokoyama T, Sato K, Sato T, Doi Y, Sugiura T. 2011

[雑誌論文] Feasibility of ICG fluorescence-guided sentinel node biopsy in animal models using the HyperEye Medical System.

Yamauchi K, Nagafuji H, Nakamura T, Sato T, Kohno N 2011

[雑誌論文] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.

Kakinuma Y, Furihata M, Akiyama T, Arikawa M, Handa T, Katare RG, Sato T. 2010

[雑誌論文] Differential regulation of TNF receptors by vagal nerve stimulation protect heart against acute ischemic injury.

Katare RG, Ando M, Kakinuma Y, Arikawa M, Yamasaki F, Sato T. 2010

[学会発表] Donepezil, an acetylcholinesterase inhibitor, reduces the risk of left ventricular free wall rupture during an acute phase of myocardial infarction by attenuating macrophage matrix metalloproteinase-9.

Arikawa M. 2010

[雑誌論文] Differential regulation of TNF receptors by vagal nerve stimulation protect heart against ccute ischemic injury.

Katare RG, Ando M, Kakinuma Y, Arikawa M, Yamasaki F, Sato T. 2010

[雑誌論文] Donepezil, an acetylcholinesterase inhibitor against Alzheimer's dementia, promotes angiogenesis in an ischemic hindlimb model.

Kakinuma Y, Furihata M, Akiyama T, Arikawa M, Handa T, Katare RG, Sato T. 2010

[学会発表] Donepezil, an acetylcholinesterase inhibitor, reduces the risk of left ventricular free wall rupture during an acute phase of myocardial infarction by attenuating macrophage matrix metalloproteinase-9.

Arikawa M 2010

[雑誌論文] A new device for the intraoperative graft assessment : The HyperEye charge-coupled device camera system.

Handa T, Katare RG, Nishimori H, Wariishi S, Fukutomi T, Yamamoto M, Sasaguri S, Sato T. 2010

[雑誌論文] A new device for the intraoperative graft assessment : The HyperEye charge-coupled device camera system.

Handa T, Katare RG, Nishimori H, Wariishi S, Fukutomi T, Yamamoto M, Sasaguri S, Sato T. 2010

[図書] 循環器内科68巻5号:アルツハイマー病に用いられるドネペジルの抗心不全作用

佐藤隆幸 2010

[雑誌論文] The effect of donepezil treatment on cardiovascular mortality.

Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A. 2010

[雑誌論文] Engineered heart tissue : A novel tool to study the ischemic changes of the heart In vitro.

Katare RG, Ando M, Kakinuma Y, Sato T 2010

[雑誌論文] The Effect of Donepezil Treatment on Cardiovascular Mortality

Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A. 2010

[学会発表] 日本医工ものつくりコモンズへの期待

佐藤隆幸 2010

[学会発表] 日本医工ものつくりコモンズへの期待

佐藤隆幸 2010

[図書] アルツハイマー病に用いられるドネペジルの抗心不全作用

佐藤隆幸 2010

[雑誌論文] Engineered heart tissue : A novel tool to study the ischemic changes of the heart In vitro.

Katare RG, Ando M, Kakinuma Y, Sato T. 2010

[雑誌論文] Vagal nerve stimulation prevents reperfusion injury through inhibition of opening of mitochondrial permeability transition pore independent of the bradycardiac effect.

Katare RG, Ando M, Kakinuma Y, Arikawa M, Handa T, Yamasaki F, Sato T. 2009

[雑誌論文] Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway.

Katare RG, Kakinuma Y, Arikawa M, Yamasaki F, Sato T. 2009

[雑誌論文] Anti-Alzheimer's drug, donepezil, markedly improves long-term survival after chronic heart failure in mice.

Handa T, Katare RG, Kakinuma Y, Arikawa M, Ando M, Sasaguri S, Yamasaki F, Sato T. 2009

[雑誌論文] Anti-Alzheimer's drug. donepezil. markedly improves long-term survival after chronic heart failure in mice.

Handa T., Katare RG., Kakinuma Y., Arikawa M., Ando M., Sasaguri S., Yamasaki F., Sato T. 2009

[雑誌論文] Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system : an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft.

Handa T., Sasaguri S, Sato T. 2009

[学会発表] HyperEye Medical Systemの開発~非分光日時分割で近赤外蛍光と可視光カラーの同時取得~

佐藤隆幸 2009

[雑誌論文] Faster and stronger vascular "Biotube" graft fabrication in vivo using a novel nicotine-containing mold.

Sakai O, Kanda K, Takamizawa K, Sato T, Yaku H, Nakayama Y. 2009

[雑誌論文] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium.

Kakinuma Y, Akiyama T, Sato T. 2009

[雑誌論文] Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system : an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft.

Handa T, Sasaguri S, Sato T. 2009

[雑誌論文] Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium.

Kakinuma Y, Akiyama T, Sato T. 2009

[学会発表] HyperEye Medical Systemの開発~非分光日時分割で近赤外蛍光と可視光カラーの同時取得~

佐藤隆幸 2009

[図書] 脊髄電気刺激療法(XV.血圧コントロールシステムとしての脊髄電気刺激療法)(森本昌宏編著)

牛田享宏, 山崎文靖, 横山武志, 佐藤隆幸 2008

[雑誌論文] Biphasic elevation of bilirubin oxidation during myocardial ischemia reperfusion.

Yamamoto M, Maeda H, Hirose N, Yamamoto M, Nakagawa A, Radhakrishnan G, Katare RG, Sato T, Yamaguchi T, Sasaguri S. 2008

撮像装置、撮像装置の制御方法および撮像装置の制御プログラム

Image pickup apparatus

開口絞り