研究成果

[雑誌論文] A new clustering method identifies multiple sclerosis‐specific T‐cell receptors

Hayashi Fumie、Isobe Noriko、Glanville Jacob、Matsushita Takuya、Maimaitijiang Guzailiayi、Fukumoto Shoko、Watanabe Mitsuru、Masaki Katsuhisa、Kira Jun‐ichi 2021

[学会発表] 第5回全国調査が示す多発性硬化症・視神経脊髄炎総患者数の増加．

磯部紀子、新野正明、松下拓也、中村優理、中島一郎、渡邉充、酒井康成、迫田礼子、中原仁、河内泉、越智博文、中辻裕司、福元尚子、林史恵、中村好一、中村幸志、坂田清美、嶋田莉奈子、松井真、吉良潤一． 2020

[雑誌論文] Environmental risk factors for multiple sclerosis in Japanese people

Sakoda A, Matsushita T, Nakamura Y, Watanabe M, Shinoda K, Masaki K, Isobe N, Yamasaki R, Kira J. 2020

[雑誌論文] Contribution of cortical lesions to cognitive impairment in Japanese patients with multiple sclerosis.

Shinoda K, Matsushita T, Nakamura Y, Masaki K, Sakai S, Nomiyama H, Togao O, Hiwatashi A, Niino M, Isobe N, Kira J. 2020

[雑誌論文] Central nervous system-specific antinuclear antibodies in patients with multiple sclerosis

Fujii T, Yamasaki R, Miyachi Y, Nagata S, Maimaitijiang G, Nakamura Y, Shinoda K, Matsushita T, Isobe N, Kira J. 2020

[雑誌論文] Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis

Zhao Y, Yamasaki R, Yamaguchi H, Nagata S, Une H, Cui Y, Masaki K, Nakamuta Y, Iinuma K, Watanabe M, Matsushita T, Isobe N, Kira J. 2020

[雑誌論文] Unique HLA haplotype associations in IgG4 anti-neurofascin 155 antibody-positive chronic inflammatory demyelinating polyneuropathy

Ogata H, Isobe N, Zhang X, Yamasaki R, Fujii T, Machida A, Morimoto N, Kaida K, Masuda T, Ando Y, Kuwahara M, Kusunoki S, Nakamura Y, Matsushita T, Kira J. 2020

[雑誌論文] Risk HLA-DRB1 alleles differentially influence brain and lesion volumes in Japanese patients with multiple sclerosis

Fukumoto S, Nakamura Y, Watanabe M, Isobe N, Matsushita T, Sakoda A, Hiwatashi A, Shinoda K, Yamasaki R, Tsujino A, Kira J. 2020

[雑誌論文] Discriminative clinical and neuroimaging features of motor-predominant hereditary diffuse leukoencephalopathy with axonal spheroids and primary progressive multiple sclerosis: A preliminary cross-sectional study

Saitoh B, Yamasaki R, Hiwatashi A, Matsushita T, Hayashi S, Mitsunaga Y, Maeda Y, Isobe N, Yoshida K, Ikeda S, Kira J. 2019

[雑誌論文] Long-term use of interferon-β in multiple sclerosis increases Vδ1(-)Vδ2(-)Vγ9(-) γδ T cells that are associated with a better outcome

Maimaitijiang G, Watanabe M, Shinoda K, Isobe N, Nakamura Y, Masaki K, Matsushita T, Yoshikai Y, Kira J. 2019

[学会発表] 表現型不一致の一卵性品胎における多発性硬化症関連Ｔ細胞受容体レパトア解析．

磯部紀子、林史恵、渡邉充、松下拓也、岡本幸市、吉良潤一． 2019

[雑誌論文] Serum GFAP and neurofilament light as biomarkers of disease activity and disability in NMOSD

Watanabe M, Nakamura Y, Michalak Z, Isobe N, Barro C, Leppert D, Matsushita T, Hayashi F, Yamasaki R, Kuhle J, Kira J. 2019

[学会発表] HLA-DRB1*04:05陽性MS患者におけるサイトメガロウイルス（CMV）関連T細胞受容体の同定．

林史恵、磯部紀子、Jacob Glanville、松下拓也、吉良潤一． 2019

[雑誌論文] Intrathecal cytokine profile in neuropathy with anti‐neurofascin 155 antibody

Ogata H, Zhang X, Yamasaki R, Fujii T, Machida A, Morimoto N, Kaida K, Masuda T, Ando Y, Kuwahara M, Kusunoki S, Nakamura Y, Matsushita T, Isobe N, Kira J. 2019

[雑誌論文] Spinal cord involvement by atrophy and associations with disability are different between multiple sclerosis and neuromyelitis optica spectrum disorder

Nakamura Y, Liu Z, Fukumoto S, Shinoda K, Sakoda A, Matsushita T, Hayashida S, Isobe N, Watanabe M, Hiwatashi A, Yamasaki R, Kira J. 2019

[学会発表] T cell receptor repertoire in a monozygotic triplet discordant for multiple Sclerosis.

Isobe N, Hayashi F, Matsushita T, Okamoto K, Kira JI. 2019

[学会発表] Increase of Mycobacterium avium subsp. Paratuberculosis (MAP) antibody in multiple sclerosis

Isobe N, Hayashi F, Cossu D, Yokoyama K, Maimatijiang G, Nakamura Y, Matsushita T, Kira JI. 2019

[学会発表] Increase of EBV lytic infection in Japanese patients with multple sclerosis.

Isobe N, Dilek HF, Sakoda A, Hayashi F, Watanabe M, Matsushita T, Kira JI. 2019

[学会発表] Disease-characteristic TCRs recognize CMV in Japanese MS with HLA-DRB1*04:05; a novel approach with GLIPH.

Hayashi F, Isobe N, Glanville J, Matsushita T, Kira J. 2019

[学会発表] 片親起源効果を用いた新規多発性硬化症リスク遺伝子の探索

磯部紀子、Andy Tsai、Stacy J Caillier、Adam Santaniello、松下拓也、吉良潤一、Stephen L. Hauser、Jorge R. Oksenberg． 2018