トップ›研究者を探す›虚血性神経細胞障害におけるMAPK情報伝達系の関わりについて

虚血性神経細胞障害におけるMAPK情報伝達系の関わりについて

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17390398
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
外科系臨床医学
脳神経外科学
研究機関 京都大学
代表研究者 野崎 和彦
研究分担者 橋本 信夫
研究分担者 高木 康志
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額（合計） 15,600,000 (直接経費 :15,600,000)
配分額（履歴） 2006年度：6,400,000 (直接経費 :6,400,000)
2005年度：9,200,000 (直接経費 :9,200,000)
キーワード 脳虚血
神経細胞死
MAPK
脳神経疾患
cerebral ischemia
ischemic tolerance
cerebral ischemia
ischemic tolerance
MAPK

研究成果

[雑誌論文] Primate embryonic stem cell-derived neuronal progenitors transplanted into ischemic brain.

Hayashi J, Takagi Y, Nishimura M, Fijimoto M, Takahashi J, Hashimoto N, Nozaki K. 2006

[雑誌論文] Administration of ex vivo-expanded bone marrow-derived endothelialprogenitor cells attenuates focal cerebral ischemia-reperfusion injury in rats.

Ohta T, Kikuta K, Imamura H, Takagi Y, Nishimura M, Arakawa Y, Hashimoto N, Nozaki K. 2006

[雑誌論文] Proliferarive activity through extracellular signal-regulated kinase of smooth muscle cells in the vascular walls of cerebral arteriovenous malformations.

Takagi Y, Kikuta K, Sadamasa N, Nozaki K, HashimotoN. 2006

[雑誌論文] Proliferarive activity through extracellular signal-regulated kinase of smooth muscle cells in the vascular walls of cerebral arteriovenous malformations.

Takagi Y et al. 2006

[雑誌論文] Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain

Takagi Y, et al. 2005

[雑誌論文] Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain.

Takagi Y et al. 2005

[雑誌論文] Activation of p38 kinase in the gerbil hippocampus showing ischemic tolerance.

Nishimura M, Sugino T, Nozaki K, Takagi Y, Hashimoto N, Moriguchi T, Nishida E. 2003

[雑誌論文] STAT1 is activated in neurons after ischemia and contributes to ischemic brain injury.

Takagi Y, Harada J, Chiarugi A, Moskowitz MA. 2002

[雑誌論文] Hypoxia-ischemia induces thioredoxin expression and nitrotyrosine formation in new-born rat brain.

Hattori I, Takagi Y, Nozaki K, Kondo N, Bai J, Nakamura H, Hashimoto N, Yodoi J. 2002

[雑誌論文] Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus.

Sugino T, Nozaki K, Takagi Y, Hattori I, Hashimoto N, Moriguchi T, Nishida E. 2000

[雑誌論文] Phosphorylation of c-Jun NH(2)-terminal kinase and p38 mitogen-activated protein kinase after transient forebrain ischemia in mice.

Takagi Y, Nozaki K, Sugino T, Hattori I, Hashimoto N. 2000

[雑誌論文] Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice.

Hattori I, Takagi Y, Nakamura H, Nozaki K, Sugino T, Nishimura M, Hashimoto N, Yodoi J.

[雑誌論文] Neuroprotective Role of A Peptide Inhibitor of c-Jun N-terminal Kinase on Global ischemia in Gerbils

Duysenbi S, Nozaki K, Takagi Y, Hayashi, HashimotoN.