トップ›研究者を探す›クロム工場従事者の気管支粘膜病変における遺伝子変化とクロム曝露量の関連性の研究

クロム工場従事者の気管支粘膜病変における遺伝子変化とクロム曝露量の関連性の研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-15591477
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
胸部外科学
研究機関 徳島大学
代表研究者 近藤 和也
研究分担者 三好 孝典
研究分担者 内原 博
研究分担者 石川 純代
研究分担者 門田 康正
研究期間 開始年月日 2003/4/1
研究期間 終了年度 2004
研究ステータス 完了 (2004/4/1)
配分額（合計） 2,100,000 (直接経費 :2,100,000)
配分額（履歴） 2004年度：700,000 (直接経費 :700,000)
2003年度：1,400,000 (直接経費 :1,400,000)
キーワード クロム肺癌
前癌病変
クロム蓄積量
蛍光X線元素分析装置
遺伝子変化
microsatellite instability
chromate lung cancer
premalignant lesions
chromate accumulation
microscopic X-ray fuorescence analyzer
genomic change
microsatellite instability

研究成果

[雑誌論文] Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers.

Kazuya Kondo 2005

[雑誌論文] Thymoma and myasthenia gravis : A clinical study of 1320 patients from Japan

Kazuya Kondo 他 2005

[雑誌論文] Thymoma and myasthenia gravis : A clinical study of 1320 patients from Japan.

Kazuya Kondo 2005

[雑誌論文] Microsatellite instability and protein expression of the DNA mismatch repair gene, hMLH1, of lung cancer in chromate-exposed workers

Kazuya Kondo 他 2005

[雑誌論文] Green fluorescent protein expression visualize mediastinal lymph node metastasis of human lung cancer cell line using orthotopic implantation.

Kazuya Kondo 他 2004

[雑誌論文] Green fluorescent protein expression visualize mediastinal lymph node metastasis of human lung cancer cell line using orthotopic implantation.

Kazuya Kondo 2004

[雑誌論文] Novel bronchofiberscopic catheter spray device allows effective anesthetic spray and sputum suctioning.

Kazuya Kondo他 2004

[雑誌論文] WHO histologic classification is a prognostic indicator in thymoma.

Kazuya Kondo 他 2004

[雑誌論文] Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.

Kazuya Kondo 2004

[雑誌論文] Novel bronchofiberscopic catheter spray device allows effective anesthetic spray and sputum suctioning.

Kazuya Kondo 2004

[雑誌論文] WHO histologic classification is a prognostic indicator in thymoma.

Kazuya Kondo他 2004

[雑誌論文] Thymidylate Synthase and Dihydropyrimidine Dehydrogenase in Non Small Cell Lung Cancer : Relationship between RNA Expression and Activity

Kazuya Kondo 他 2004

[雑誌論文] WHO histologic classification is a prognostic indicator in thymoma.

Kazuya Kondo 2004

[雑誌論文] Tree-dimensional imaging of thoracic diseases with 2004. multidetector row CT.

Kazuya Kondo他 2004

[雑誌論文] Orthotopically implanted SID mice using human lung cancer cell lines and its metastatic patterns.

Kazuya Kondo 2004

[雑誌論文] Tree-dimensional imaging of thoracic diseases with 2004. multidetector row CT.

Kazuya Kondo 他 2004

[雑誌論文] Novel bronchofiberscopic catheter spray device allows effective anesthetic spray and sputum suctioning.

Kazuya Kondo 他 2004

[雑誌論文] Thymidylate Synthase and Dihydropyrimidine Dehydrogenase in Non Small Cell Lung Cancer : Relationship between RNA Expression and Activity

Kazuya Kondo 2004

[雑誌論文] Computed tomography-guide drainage for large pulmonary bullae.

Kazuya Kondo 2004

[雑誌論文] Thymidylate Synthase and Dihydropyrimidine Dehydrogenase in Non Small Cell Lung Cancer : Relationship between RNA Expression and Activity

Kazuya Kondo他 2004

[雑誌論文] Green fluorescent protein expression visualize mediastinal lymph node metastasis of human lung cancer cell line using orthotopic implantation.

Kazuya Kondo他 2004

[雑誌論文] Orthotopically implanted SID mice using human lung cancer cell lines and its metastatic patterns.

Kazuya Kondo 他 2004

[雑誌論文] Computed tomography-guide drainage for large pulmonary bullae

Kazuya Kondo 他 2004

[雑誌論文] Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.

Kazuya Kondo 他 2004

[雑誌論文] Orthotopically implanted SID mice using human lung cancer cell lines and its metastatic patterns.

Kazuya Kondo他 2004

[雑誌論文] Tree-dimensional imaging of thoracic diseases with multidetector row CT.

Kazuya Kondo 2004

[雑誌論文] Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.

Kazuya Kondo他 2004

[雑誌論文] Computed tomography-guide drainage for large pulmonary bullae

Kazuya Kondo他 2004

[雑誌論文] Increased expression of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 correlate with poor prognostic variables in thymic epithelial tumors.

Kazuya Kondo 2003

[雑誌論文] Increased expression of matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 correlate with poor prognostic variables in thymic epithelial tumors

Kazuya Kondo 他 2003

[雑誌論文] Fatal air embolism during CT guided pulmonary marking with a hook typed marker.

Kazuya Kondo 他 2003

[雑誌論文] Microscopical analysis of the chromium content in the bronchial and lung tissues of chromate workers.

Kazuya Kondo 他 2003

[雑誌論文] DNA adducts detected in human gastric mucosa.

Kazuya Kondo 2003

[雑誌論文] DNA adducts detected in human gastric mucosa.

Kazuya Kondo 他 2003

[雑誌論文] Therapy for thymic epithelial tumors. A clinical study of 1320 Patients from Japan

Kazuya Kondo 他 2003

[雑誌論文] Fatal air embolism during CT guided pulmonary marking with a hook typed marker.

Kazuya Kondo 2003

[雑誌論文] Lymphogenous and hematogenous metastasis of thymic epithelial tumors.

Kazuya Kondo 2003

[雑誌論文] Microscopical analysis of the chromium content in the bronchial and lung tissues of chromate workers.

Kazuya Kondo 2003

[雑誌論文] Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues.

Kazuya Kondo 2003

[雑誌論文] Therapy for thymic epithelial tumors. A clinical study of 1320 patients from Japan.

Kazuya Kondo 2003

[雑誌論文] Lymphogenous and hematogenous metastasis of thymic epithelial tumors.

Kazuya Kondo 他 2003

[雑誌論文] Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues.

Kazuya Kondo 他 2003

[雑誌論文] Microscopical analysis of the chromium content in the chromium-induced malignant and premalignant bronchial lesions of the rat.

Kazuya Kondo 他

[雑誌論文] Microscopical analysis of the chromium content in the chromium-induced malignant and premalignant bronchial lesions of the rat.

Kazuya Kondo