トップ研究者を探すPathophysiological investigation of bone cell communications regulated by chemokine network

Pathophysiological investigation of bone cell communications regulated by chemokine network

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-26861549
研究種目 若手研究(B)
研究分野 生物系
医歯薬学
歯学
形態系基礎歯科学
研究機関 愛媛大学
代表研究者 李 智媛
研究期間 開始年月日 2014/4/1
研究期間 終了年度 2015
研究ステータス 完了 (2015/4/1)
配分額(合計) 3,900,000 (直接経費 :3,000,000、間接経費 :900,000)
配分額(履歴) 2015年度:1,950,000 (直接経費 :1,500,000、間接経費 :450,000)
2014年度:1,950,000 (直接経費 :1,500,000、間接経費 :450,000)
キーワード osteoclast
chemokine
CCR5
RANKL
cytoskeleton
bone
small GTPase

研究成果

[学会発表] Quantitative illumination on bone histology and cell biology by fluorescence imaging

Ji-Won Lee, Tadahiro Iimura 2015

[学会発表] Roles of C-C chemokine receptor 5, a co-receptor of HIV, -mediated signal in locomotion of osteoclasts and bone resorption

Ji-Won Lee 2015

[学会発表] Ji-Won Lee, Hoshino Akiyoshi, Saitou Takashi, Inoue Kazuki, Uehara Shunsuke, Kobayashi Yasuhiro, Ueha Satoshi, Matsushima Kouji, Ito Masako, Yamaguchi Akira, Imai Yuuki, Iimura Tadahiro

Ji-Won LeeJi-Won Lee, Hoshino Akiyoshi, Saitou Takashi, Inoue Kazuki, Uehara Shunsuke, Kobayashi Yasuhiro, Ueha Satoshi, Matsushima Kouji, Ito Masako, Yamaguchi Akira, Imai Yuuki, Iimura Tadahiro 2015

[雑誌論文] Quantitative in situ fluorescence imaging to unveil the morphological and functional heterogeneity of osteocytes

Lee JW, Iimura T 2015

[学会発表] 蛍光細胞イメージングと骨形態計測で見る骨代謝におけるケモカインシグナルの役割

Ji-Won Lee 2015

[学会発表] Roles of CCR5, a co-receptor of HIV, in regulation of functional motility of osteoclasts

Ji-Won Lee, Hoshino Akiyoshi, Saitou Takashi, Inoue Kazuki, Uehara Shunsuke, Kobayashi Yasuhiro, Ueha Satoshi, Matsushima Kouji, Ito Masako, Yamaguchi Akira, Imai Yuuki, Iimura Tadahiro 2015

[雑誌論文] Quantitative in situ fluorescence imaging to unveil the morphological and function heterogeneity of osteocytes

Ji-Won Lee, Tadahiro Iimura 2015

[学会発表] DMP1は骨細胞におけるFGF23産生の抑制因子である-蛍光3次元形態計測と細胞生物学的アプローチ-

李智媛、山口朗、飯村忠浩 0

[学会発表] Three-dimensional fluorescence morphometry reveals functional heterogeneity of osteocytes in FGF23 production regulated by DMP1

Ji-Won Lee, Tadahiro Iimura 0

[学会発表] A possible role of DMP1 as a negative regulator of FGF23 production in functional heterogeneity osteocytes: Three-dimensional morphological approaches

Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura 0

[学会発表] Super-resolution analysis of cell cycle phase-dependent phosphorylation of Smads

Ji-Won Lee, Takeshi Imamura, Tadahiro Iimura 0

[学会発表] Cell cycle phase-dependent phosphorylation of Smads in skeletal cells

Ji-Won Lee, Takeshi Imamura, Tadahiro Iimura 0