研究成果

[雑誌論文] Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression

Yamashita M, Inoue K, Saeki N, Ideta-Otsuka M, Yanagihara Y, Sawada Y, Sakakibara I, Lee JW, Ichikawa K, Kamei Y, Iimura T, Igarashi K, Takada Y, Imai Y 2018

[学会発表] The HIV co-receptor CCR5 regulates cellular pathways required for osteoclast function

Ji-Won Lee, Shunsuke Uehara, Yasuhiro Kobayashi, Yuuki Imai and Tadahiro Iimura 2018

[雑誌論文] 骨組織の顕微鏡研究

李 智 媛、 飯 村 忠 浩 2018

[雑誌論文] テリパラチドの高頻度投与は皮質骨空隙形成を誘導する

高 倉 綾、李 智 媛、 山 根 宏 志、高 尾 亮 子、飯 村 忠 浩 2018

[学会発表] マルチモード蛍光観察による新規の骨代謝病態機能探索

飯村忠浩　李　智媛 2018

[雑誌論文] Shedding quantitative fluorescence light on novel regulatory mechanisms in skeletal biomedicine and biodentistry.

Lee JW, Iimura T. 2017

[学会発表] Requirement of CCR5, a co-receptor of HIV, for the functional cellular architecture of osteoclasts, providing experimental evidences for the direct association between loss of CCR5 and resistance to bone loss

Lee JW, Inoue K, Uehara, S, Kobayashi Y, Imai Y, Iimura T 2017

[学会発表] 骨形態計測法で明らかになったHIV治療薬標的分子CCR5の破骨細胞機能分化における必須の機能

李　智媛　飯村忠浩 2017

[学会発表] マウスジェネティクスを用いたHIV感染患者の骨病態解明

飯村忠浩　李智媛 2017

[雑誌論文] Acute development of cortical porosity and endosteal naive bone formation from the daily but not weekly short-term administration of PTH in rabbit.

Yamane H, Takakura A, Shimadzu Y, Kodama T, Lee JW, Isogai Y, Ishizuya T, Takao-Kawabata R, Iimura T. 2017

[学会発表] C-C chemokine receptor 5, a co-receptor of HIV, -mediated signal is required for geometric architecture and function of osteoclasts, thus for RANKL-induced bone destruction

Lee JW, Hoshino A, Saitou T, Inoue K, Uehara, S, Kobayashi Y, Matsushima K, Imai Y, Iimura T. 2016

[学会発表] 機能的生細胞イメージングとオミクス解析による破骨細胞調節機能の解明

李智媛　飯村忠浩 2016

[学会発表] Essential roles of C-C chemokine signaling in mature osteoclast function

Lee JW, Hoshino A, Kobayashi Y, Uehara, S, Imai Y, Iimura T. 2016

[学会発表] Roles of Chemokine-mediated signaling in architectual funstion of osteoclasts

李智媛、星野昭芳、井上和樹、上原俊輔、小林康浩、山口朗、今井祐記、飯村忠浩 2016

[学会発表] Novel regulatory mechanisms of osteoclast function, as revealed by combinatorial approaches of functional live-imaging and molevular omics

Lee JW, Hoshino A, Uehara, S, Kobayashi Y, Imai Y, Iimura T. 2016

[学会発表] Essential role of C-C chemokine-mediated signaling in mature osteoclast function

李智媛　飯村忠浩 2016

[学会発表] マルチモーダル超解像法を用いた骨系細胞の機能解析

飯村忠浩　李智媛 2016

[学会発表] Quantitative illumination of bone histology and cell biology by fluorescence imaging

Ji-Won Lee, Tadahiro Iimura 2015

[学会発表] マルチスケール画像解析の骨生物医学への応用展開

飯村忠浩　李智媛 2015

[雑誌論文] Changes in the spatial distribution of sclerostin in the osteocytic lacuno-canalicular system in alveolar bone due to orthodontic forces, as detected on multimodal confocal fluorescence imaging analyses.

Nishiyama Y, Matsumoto T, Lee JW, Saitou T, Imamura T, Moriyama K, Yamaguchi A, Iimura T. 2015

[学会発表] C-C chemokine receptor 5, a co-receptor of HIV, -mediated signal　regulates bone resorption via locomotion of osteoclasts

Lee JW et al. 2015

[雑誌論文] Functional heterogeneity of osteocytes in FGF23 production: the possible involvement of DMP1 as a direct negative regulator.

Lee JW, Yamaguchi A, Iimura T. 2014

[学会発表] Super-resolution analyses of Cell cycle phase-dependent phosphorylation of Smads

i-Won Lee, Takeshi Imamura, Tadahiro Iimura 0

[学会発表] DMP1は骨細胞におけるFGF23産生の抑制因子である－蛍光3次元形態計測と細胞生物学的アプローチ－

李智媛、山口朗、飯村忠浩 0

[学会発表] A possible role of DMP1 as a negative regulator of FGF23 production in functional heterogeneity osteocytes: Three-dimensional morphological approaches

Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura 0

[学会発表] Three-dimensional fluorescence morphometry reveals functional heterogeneity of osteocytes in FGF23 production　regulated by DMP1

Ji-Won Lee, Akira Yamaguchi, Tadahiro Iimura 0

[学会発表] Cell cycle phase-dependent phosphorylation of Smads in skeletal cells

Ji-Won Lee, Takeshi Imamura, Tadahiro Iimura 0