トップ›研究者を探す›強度近視における脈絡膜新生血管の発生機序の解明

強度近視における脈絡膜新生血管の発生機序の解明

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-24592624
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
眼科学
研究機関 京都大学
代表研究者 山城 健児
研究分担者 村上 智昭
研究期間 開始年月日 2012/4/1
研究期間 終了年度 2014
研究ステータス 完了 (2014/4/1)
配分額（合計） 5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
配分額（履歴） 2014年度：1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
2013年度：2,080,000 (直接経費 :1,600,000、間接経費 :480,000)
2012年度：1,690,000 (直接経費 :1,300,000、間接経費 :390,000)
キーワード 強度近視
WNT7B
脈絡膜新生血管

研究成果

[雑誌論文] Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations.

Huang LZ, Li YJ, Xie XF, Zhang JJ, Cheng CY, Yamashiro K, Chen LJ, Ma XY, Cheung CM, Wang YS, Zhang CF, Bai YJ, Hou J, Chen XL, Qi Y, Li SS, Sun YY, Mei JP, Cheng Y, Yu WZ, Hu XB, Zhuang FF, Fan L, Lu Y, Sun XH, Zhu XJ, Shen DF, Chan CC, Zhao MW, Yoshimura N, Pang CP, Wong TY, Khor CC, Zhang K, Zhou P, Li XX. 2015

[雑誌論文] New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Cheng CY, Yamashiro K, et al. 2015

[雑誌論文] Calcium, ARMS2 Genotype, and Chlamydia Pneumoniae Infection in Early Age-Related Macular Degeneration: a Multivariate Analysis from the Nagahama Study.

Nakata I, Yamashiro K, Kawaguchi T, Nakanishi H, Akagi-Kurashige Y, Miyake M, Tsujikawa A, Yamada R, Matsuda F, Yoshimura N; Nagahama Study Group. 2015

[雑誌論文] Vascular endothelial growth factor gene and the response to anti-vascular endothelial growth factor treatment for choroidal neovascularization in high myopia.

Miyake M, Yamashiro K, Akagi-Kurashige Y, Kumagai K, Nakata I, Nakanishi H, Oishi A, Tsujikawa A, Yamada R, Matsuda F, Yoshimura N. 2014

[雑誌論文] Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy.

Nakata I, Yamashiro K, Kawaguchi T, Gotoh N, Nakanishi H, Akagi-Kurashige Y, Miyake M, Tsujikawa A, Oishi A, Saito M, Iida T, Yamada R, Matsuda F, Yoshimura N; Nagahama Study Group. 2013

[雑誌論文] Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects.

Oishi M, Yamashiro K, Miyake M, Akagi-Kurashige Y, Kumagai K, Nakata I, Nakanishi H, Yoshikawa M, Oishi A, Gotoh N, Tsujikawa A; Nagahama Study Group, Yamada R, Matsuda F, Yoshimura N. 2013

[雑誌論文] Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia.

Khor CC, Miyake M, Chen LJ, Shi Y, Barathi VA, Qiao F, Nakata I, Yamashiro K, Zhou X, Tam PO, Cheng CY, Tai ES, Vithana EN, Aung T, Teo YY, Wong TY, Moriyama M, Ohno-Matsui K, Mochizuki M, Matsuda F; Nagahama Study Group, Yong RY, Yap EP, Yang Z, Pang CP, Saw SM, Yoshimura N. 2013

[雑誌論文] Prevalence and characteristics of age-related macular degeneration in the Japanese population: the Nagahama study.

Nakata I, Yamashiro K, Nakanishi H, Akagi-Kurashige Y, Miyake M, Tsujikawa A, Matsuda F, Yoshimura N; Nagahama Cohort Research Group. 2013

[雑誌論文] Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.

Fan Q, Barathi VA, Cheng CY, Zhou X, Meguro A, Nakata I, Khor CC, Goh LK, Li YJ, Lim W, Ho CE, Hawthorne F, Zheng Y, Chua D, Inoko H, Yamashiro K, et al 2012

[雑誌論文] Association of paired box 6 with high myopia in Japanese.

Miyake M, Yamashiro K, Nakanishi H, Nakata I, Akagi-Kurashige Y, Tsujikawa A, Moriyama M, Ohno-Matsui K, Mochizuki M, Yamada R, Matsuda F, Yoshimura N. 2012