蛍光標識タイムラプス記録法を用いたプロサポシンの細胞内動態の追跡

トップ›研究者を探す›蛍光標識タイムラプス記録法を用いたプロサポシンの細胞内動態の追跡

蛍光標識タイムラプス記録法を用いたプロサポシンの細胞内動態の追跡

代表研究者	小林直人
研究課題番号	KAKENHI-PROJECT-24590254
研究種目	基盤研究(C)
研究分野	生物系医歯薬学基礎医学解剖学一般(含組織学・発生学)
研究機関	愛媛大学
研究期間開始年月日	2012/4/1
研究期間終了年度	2014
研究ステータス	完了 (2014/4/1)
配分額（合計）	5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
配分額（履歴）	2014年度：780,000 (直接経費 :600,000、間接経費 :180,000) 2013年度：2,210,000 (直接経費 :1,700,000、間接経費 :510,000) 2012年度：2,340,000 (直接経費 :1,800,000、間接経費 :540,000)
キーワード	神経栄養因子神経保護作用プロサポシンプロサポシン受容体培養細胞細胞内動態遺伝子導入パーキンソン病タイムラプス栄養因子細胞培養蛍光色素

研究成果

[雑誌論文] A prosaposin-derived peptide alleviates kainic acid-induced brain injury

Nabeka H, Shiomokawa T, Doihara T, Saito S, Wakisaka H, Hamada F, Kobayashi N,Matsuda S 2015

[雑誌論文] Prosaposin overexpression following kainic acid-induced neurotoxicity.

Nabeka H, Uematsu K, Takechi H, Shimokawa T, Yamamiya K, Li C, Doihara T, Saito S, Kobayashi N, Matsuda S 2014

[雑誌論文] Temporal Changes in Prosaposin Expression in the Rat Dentate Gyrus after Birth

M Morishita, H Nabeka, T Shimokawa, K Miyawaki, 　T Doihara, S Saito, N Kobayashi, S Matsuda 2014

[学会発表] タイムラプス顕微鏡を用いたプロサポシンの細胞内動態の観察

定成裕子、鍋加浩明、土居原拓也、下川哲哉、小林直人、松田正司 2014

[雑誌論文] Differential expression of the alternatively spliced forms of prosaposin mRNAs in the rat choroid plexus

S Saito, K Saito, H Nabeka, T Shimokawa, N Kobayashi, S Matsuda 2014

[雑誌論文] Prosaposin expression in the regenerated muscles of mdx and cardiotoxin-treated mice

Cheng Li, Hui-ling Gao, Tetsuya Shimokawa, Hiroaki Nabeka, Fumihiko Hamada, Hiroaki Araki, Ya-ming Cao, Naoto Kobayashi, Seiji Matsuda 2013

[学会発表] Differential expression of prosaposin in the central nervous system of juvenile and dystrophic mdx mice.

高慧玲、李成、下川哲哉、鍋加浩明、土居原拓也、小林直人、松田正司 2013

[雑誌論文] Prosaposin-derived peptide alleviates ischaemia-induced hearing loss

T Terashita, S Saito, H Nabeka, N Hato, H Wakisaka, T Shimokawa, N Kobayashi, K Gyo, S Matsuda 2013

[学会発表] 顕顕微鏡用培養装置を使用したプロサポシンの経時的観察

定成裕子, 鍋加浩明, 土居原拓也, 下川哲哉, 小林直人, 松田正司 2013

[雑誌論文] Decrease in prosaposin in the dystrophic mdx mouse brain

Hl Gao, C Li, H Nabeka, T Shimokawa, N Kobayashi, S Saito, ZY Wang, YM Cao, S Matsuda 2013

[学会発表] Prosaposin expression in the regenerated muscles of mdx and cardiotoxin-treated mice.

李成、高慧玲、下川哲哉、鍋加浩明,濱田文彦、荒木博陽、曹雅明、小林直人、松田正司 2013

[雑誌論文] Prosaposin expression in the regenerated muscles of mdx and cardiotoxin-treated mice.

Li Cheng, Gao Hui-ling, Shimokawa T, Nabeka H, Hamada F, Araki H, Cao Ya-ming, Kobayashi N, Matsuda S. 2013

[学会発表] プロサポシン及びサポシンの神経保護作用の機能解析

鍋加浩明, 土居原拓也, 下川哲哉, 小林直人, 松田正司 2013

[雑誌論文] Distribution of prosaposin in rat lymphatic tissues.

Shimokawa T, Nabeka H, Yamamiya K, Wakisaka H, Takeuchi T, Kobayashi N, Matsuda S. 2013

[雑誌論文] Distribution of prosaposin in rat lymphatic tissues

T Shimokawa, H Nabeka, K Yamamiya, H Wakisaka, T Takeuchi, N Kobayashi, S Matsuda 2013

[雑誌論文] 鳥類神経系を用いた発生学研究

松田正司、鍋加浩明、王敏、下川哲哉、土居原拓也、山宮公子、脇坂浩之、小林直人 2012

[雑誌論文] Lectin binding pattern of gastric mucosa of pacific white-sided dolphin

Shimokawa T, Doihara T, Makara M, Miyawaki K, Nabeka H, Wakisaka H, Kobayashi N, Matsuda S. 2012

[学会発表] Age- and sex-dependent changes in prosaposin and its receptors in the lacrimal glands of rats

Farzana Islam, MSI Khan, Xuan Li, Tetsuya Shimokawa, Hiroaki Nabeka, Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Prosaposin mRNA and protein expression in rat testis

Kimiko Yamamiya, Tetsuya Shimokawa, Hiroaki Nabeka, Takuya Doihara, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Chronological changes in prosaposin receptors immunoreactivity in rat brain after birth

Aika Yorozuya, Hiroaki Nabeka, Tetsuya Shimokawa, Khan MSI, Xuan Li,Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Prosaposin and its receptors in the spleen

Mitsuaki Takezawa, Tetsuya Shimokawa, Hiroaki Nabeka, Khan MSI, Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Prosaposin and its receptors in the cerebellum after kainic acid injection

Xuan Li, Hiroaki Nabeka, Tetsuya Shimokawa, Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Prosaposin and its receptors in the facial nucleus after facial nerve transection

Jyoji Kunihiro, Hiroaki Nabeka, Tetsuya Shimokawa, Xuan Li, Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda 0

[学会発表] Prosaposin and its receptors in the kidney

Haruka Watanabe,Tetsuya Shimokawa, Hiroaki Nabeka, Khan MSI, Takuya Doihara, Kimiko Yamamiya, Fumihiko Hamada, Seiji Matsuda, Naoto Kobayashi 0