研究成果

[雑誌論文] Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model

Iwami K, Natsume A, Ohno M, Ikeda H, Mineno J, Nukaya I, Okamoto S, Fujiwara H, Yasukawa M, Shiku H, Wakabayashi T 2013

[雑誌論文] HLA-restricted presentation of WT1 tumor antigen in B-lymphoblastoid cell lines established using a maxi-EBV system.

Kanda, T, et al. 2012

[雑誌論文] A promising vector for TCR gene therapy: differential effect of siRNA, 2A peptide, and disulfide bond on the introduced TCR expression.

Okamoto S, et al. 2012

[雑誌論文] Gemcitabine enhances Wilms’ tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response.

Takahara A, Yasukawa M, et al. 2011

[雑誌論文] Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis.

An J, Yasukawa M, et al. 2011

[雑誌論文] Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis

An, J., Fujiwara, H., Suemori, K., Niiya, T., Azuma, T., Tanimoto, K., Ochi, T., Akatsuka, Y., Mineno, J., Ozawa, H., Ishikawa, F., Kuzushima, K. and Yasukawa, M. 2011

[雑誌論文] Feasibility of gene-immunotherapy using WT1-specific T-cell receptor gene transfer for infant acute lymphoblastic leukemia with MLL gene rearrangement.

Nagai K, Yasukawa M, et al. 2011

[雑誌論文] Adoptive T-cell immunotherapy using T-cell receptor gene transfer: aiming at a cure for cancer

Yasukawa, M., Ochi, T, and Fujiwara, H. 2011

[雑誌論文] A new four-way variant t(5;17;15;20)(q33;q12;q22;q11.2) in acute promyelocytic leukemia

Yamanouchi, J., Hato, T., Niiya, T., Miyoshi, K., Azuma, T., Sakai, I. and Yasukawa, M. 2011

[学会発表] Redirected CD4+ T Cells Using WT1-Specific T-Cell Receptor Gene Transfer Can Supply Multifactorial Help to Enhance the Anti-Leukemia Reactivity Mediated by Similarly Redirected CD8+ T Cells Using the Identical Gene Transfer

Ochi T, Yasukawa M, et al. 2011

[雑誌論文] Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked anti-leukemia reactivity and safety.

Ochi T, Yasukawa M, et al. 2011

[学会発表] Forced Expression of CC Chemokine Receptor 2 Enhances Anti-Cancer Reactivity Mediated by T Lymphocytes Beforehand Redirected Toward WT1 Inside the Tumor Microenvironment

Asai A, Yasukawa M, et al. 2011

[学会発表] Human Telomerase Reverse Transcriptase-Specific T-Cell Receptor Gene Transfer Redirects T-Lymphocytes to Exert Effective Antitumor Reactivity Against Adult T-Cell Leukemia

Miyazaki Y, Yasukawa M, et al. 2011

[雑誌論文] Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production

Hasegawa H, Yasukawa M, et al. 2011