研究成果

[雑誌論文] The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K. 2014

[雑誌論文] The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment

Iwamoto C, Takenaka K,以下14名 2014

[学会発表] BALB/c- specific L29V polymorphism in SIRPA determines the efficient engraftment of human hematopoiesis in xenogeneic model

Iwamoto C, Takenaka K, et al 2013

[雑誌論文] Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation.

Shima T, Miyamoto T, Kikushige Y, Mori Y, Kamezaki K, Takase K, Henzan H, Numata A, Ito Y, Takenaka K, Iwasaki H, Kamimura T, Eto T, Nagafuji K, Teshima T, Kato K, Akashi K 2013

[学会発表] 同種造血幹細胞移植後早期のCMV再活性化が急性白血病再発に及ぼす影響

竹中克斗 2013

[雑誌論文] Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation.

Shima T, Miyamoto T, Kikushige Y, Mori Y, Kamezaki K, Takase K, Henzan H, Numata A, Ito Y, Takenaka K, Iwasaki H, Kamimura T, Eto T, Nagafuji K, Teshima T, Kato K, Akashi K. 2013

[雑誌論文] Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment

Yamauchi T, Takenaka ,以下12名 2013

[学会発表] Fibrotic tissues in human primary myelofibrosis with JAK2 V617F are developed clonally from malignant hematopoietic stem cells

amauchi T, Shima T, Takenaka K, et al 2013

[学会発表] Cytomegalovirus Reactivation After Allogeneic Stem Cell Transplantation Is Associated With a Reduced Risk Of Relapse In Patients With Acute Myeloid Leukemia

Katsuto Takenaka 2013

[雑誌論文] Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.

Yamauchi T, Takenaka K, Urata S, Shima T, Kikushige Y, Tokuyama T, Iwamoto C, Nishihara M, Iwasaki H, Miyamoto T, Honma N, Nakao M, Matozaki T, Akashi K 2013

[学会発表] 教育講演48　移植後のウイルス感染症

竹中克斗 2013

[雑誌論文] Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker⁺ cardiomyocytes in vivo.

Fukata M, Ishikawa F, Najima Y, Yamauchi T, Saito Y, Takenaka K, Miyawaki K, Shimazu H, Shimoda K, Kanemaru T, Nakamura K, Odashiro K, Nagafuji K, Harada M, Akashi K. 2013

[雑誌論文] Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.

Yamauchi T, Takenaka K, Urata S, Shima T, Kikushige Y, Tokuyama T, Iwamoto C, Nishihara M, Iwasaki H, Miyamoto T, Honma N, Nakao M, Matozaki T, Akashi K. 2013

[学会発表] Cytomegalovirus reactivation after allogeneic stem cell transplantation is associated with a reduced risk of relapse in patients with acute myeloid leukemia

Katsuto Takenaka 2013

[学会発表] ヒト造血アッセイのための異種移植システムの進歩

竹中克斗 2012

[雑誌論文] 白血病幹細胞

竹中克斗、赤司浩一 2012

[雑誌論文] Initial low-dose valganciclovir as a preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.

Takenaka K, Nagafuji K, Takase K, Kamimura T, Mori Y, Ito Y, Nishi Y, Henzan H, Kato K, Harada N, Eto T, Miyamoto T, Teshima T, Akashi K. 2012

[雑誌論文] Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis

Kuriyama T, Takenaka K,以下12名 2012

[学会発表] 急性骨髄性白血病幹細胞遺伝子発現プロファイルの臨床的意義

竹中克斗 2012

[雑誌論文] Initial low-dose valganciclovir as a preemptive therapy is effective for cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients

Takenaka K,以下13名 2012

[雑誌論文] 骨髄不全症候群

竹中克斗 2012

[雑誌論文] Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.

Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K 2012

[学会発表] Hemophagocytic lymphohistiocytosis is caused by engulfment of hematopoietic stem cells by macrophages through stem cell-specific suppression of CD47 under influence of cytokine deregulation

Kuriyama T, Takenaka K, et al 2011

[学会発表] The Efficient Engraftment of Human Hematopoiesis in the Balb/c Strain Is Mounted by Balb/c-Specific SIRPA Polymorphism That Enhances Binding Affinity to Human CD47

Iwamoto C, Takenaka K, et al 2011

[雑誌論文] Stem cell gene expression programs influence clinical outcome in human leukemia

Eppert K, Takenaka K, Lechman ER, et 2011

[学会発表] Hemophagocytic Lymphohistiocytosis Is Caused by Engulfment of Hematopoietic Stem Cells by Macrophages Through Stem Cell-Specific Suppression of CD47 Under Influence of Cytokine Deregulation

Kuriyama T, Takenaka K, et al 2011

[雑誌論文] Stem cell gene expression programs influence clinical outcome in human leukemia

Eppert K, Takenaka K,以下17名 2011

[雑誌論文] Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

Kikushige Y, Ishikawa F, Miyamoto T, Shima T, Urata S, Yoshimoto G, Mori Y, Iino T, Yamauchi T, Eto T, Niiro H, Iwasaki H, Takenaka K, Akashi K 2011

[学会発表] The efficient engraftment of human hematopoiesis in the Balb/c strain is mounted by Balb/c-specific SIRPA polymorphism that enhances binding affinity to human CD47

Iwamoto C, Takenaka K, et al 2011

[学会発表] 日本造血細胞移植学会ガイドライン　サイトメガロウイルス感染症

竹中克斗