トップ研究者を探す免疫記憶CD8T細胞の形成および維持機構におけるオステオポンチンの機能解析

免疫記憶CD8T細胞の形成および維持機構におけるオステオポンチンの機能解析

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-22790449
研究種目 若手研究(B)
研究分野 生物系
医歯薬学
基礎医学
免疫学
研究機関 北海道大学
代表研究者 森本 純子
研究期間 開始年月日 2010/4/1
研究期間 終了年度 2011
研究ステータス 完了 (2011/4/1)
配分額(合計) 3,900,000 (直接経費 :3,000,000、間接経費 :900,000)
配分額(履歴) 2011年度:1,820,000 (直接経費 :1,400,000、間接経費 :420,000)
2010年度:2,080,000 (直接経費 :1,600,000、間接経費 :480,000)
キーワード 免疫記憶
ウイルス感染
オステオポンチン
記憶CD8T細胞
二次免疫応答
CD8T細胞
記憶免疫
二次感染

研究成果

[学会発表] Osteopontin modulates the generation of memory CD8^+T cells during influenza virus infection

Junko Morimoto, Kayoko Sato, Yosuke Nakayama, Chiemi Kimura, Kiichi Kajino, Tadaaki Miyazaki, Uede Toshimitsu 2011

[学会発表] Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice

Keiko Danzaki, Yutaka Matsui, Junko Morimoto, Yoichiro Iwakura, Toshimitsu Uede 2011

[雑誌論文] Uede T. Alpha9beta1 integrin-mediated signaling serves as an intrinsic regulator of pathogenic Th17 cell generation

Kanayama M, Morimoto J, Matsui Y, Ikesue M, Danzaki K, Kurotaki D, Ito K, Yoshida T, and Uede T 2011

[学会発表] Osteopontin modulates the generation of memory CD8T cells during influenza virus infection

J.Morimoto 2011

[雑誌論文] CSF-1-dependent red pulp macrophages regulate CD4 T cell responses

Kurotaki D., Kon S., Bae K., Ito K., Matsui Y., Nakayama Y., Kanayama M., Kimura C., Narita Y., Nishimura T., Iwabuchi K., Mack M., Van Rooijen N., Sakaguchi S., Uede T., Morimoto J 2011

[雑誌論文] Osteopontin modulates the generation of memory CD8T cells during influenza virus infection

J.Morimoto 2011

[雑誌論文] Syndecan-4 Deficiency Limits Neointimal Formation After Vascular Injury by Regulating Vascular Smooth Muscle Cell Proliferation and Vascular Progenitor Cell Mobilization

Ikesue M., Matsui Y., Ohta D., Danzaki K., Ito K., Kanayama M., Kutotaki D., Morimoto J., Kojima T., Tsutsui H., Uede T. 2011

[雑誌論文] Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction

Matsui Y, Ikesue M, Danzaki K, Morimoto J, Sato M, Tanaka S, Kojima T, Tsutsui H, and Uede T 2011

[学会発表] Alpha9beta1 Integrin-Mediated Signaling Serves as an Intrinsic Regulator of Pathogenic

Masashi Kanayama, Junko Morimoto, Yutaka Matsui, Toshimichi Yoshida and Toshimitsu Uede 2011

[雑誌論文] Osteopontin modulates the generation of memory CD8^+T cells during influenza virus infection

Morimoto J, Sato K, Nakayama Y, Kimura C, Kajino K, Matsui Y, Miyazaki T, and Uede T 2011

[学会発表] The role of Syndecan-4 in the development of Rheumatoid Arthritis

Tsutomu Endo, Masashi Kanayama, Koyu Ito, Junko Morimoto, Norimasa Iwasaki, Akio Minami, Toshimitsu Uede 2011

[学会発表] The role of osteopontin in the generation of virus-specific memory CD8T cells

Junko Morimoto, Kayoko Sato, Yosuke Nakayama, Hiroshi Kida, Tadaaki Miyazaki, Toshimitsu Uede 2010

[雑誌論文] Osteopontin ; as a target molecule for the treatment of inflammatory diseases.

J.Morimoto 2010

[学会発表] The role of osteopontin in the generation of virus-specific memory CD8 T cells

Junko Morimoto 2010

[図書] Osteopontin ; as a target molecule for the treatment of inflammatory diseases

Morimoto J, Kon S, Matsui Y, Uede T 2010

[雑誌論文] Blockade of interaction of alpha9 integrin with its ligands hinders the formation of granulation in cutaneous wound healing

Nakayama Y, Kon S, Kurotaki D, Morimoto J, . Matsui Y, and Uede T 2010

[雑誌論文] Prevention of experimental autoimmune uveoretinitis by blockade of osteopontin with small interfering RNA

Iwata D, Kitamura M, Kitaichi N, Saito Y, Kon S, Namba K, Morimoto J, Ebihara A, Kitamei H, Yoshida K, Ishida S, Ohno S, Uede T, Onoe K, and Iwabuchi K 2010

[学会発表] Abrogation of integrinα9β1-mediated signaling skews the generation of functional Th17 cells in regional lymph nodes of arthritic mice

Masashi Kanayama, Junko Morimoto, Toshimitsu Uede 2010

[学会発表] The role of osteopontin in the generation of virus-specific memory CD8 T cells

Junko Morimoto 2010

[図書] Role of matricellular proteins in cardiac tissue remodeling after myocardial infarction

Matsui Y, Morimoto J, Uede T 2010

[図書] 臨床免疫・アレルギー科

森本純子、黒滝大翼、上出利光