研究成果

[雑誌論文] Cathepsin K Is Involved in Development of Psoriasis-like Skin Lesions through TLR-Dependent Th17 Activation.

Hirai T, Kanda T, Sato K, Takaishi M, Nakajima K, Yamamoto M, Kamijima R, Digiovanni J, Sano S. 2013

[雑誌論文] Barrier abnormality due to ceramide deficiency leads to psoriasiform inflammation in a mouse model.

Nakajima K, Terao M, Takaishi M, Kataoka S, Goto-Inoue N, Setou M, Horie K, Sakamoto F, Ito M, Azukizawa H, Kitaba S, Murota H, Itami S, Katayama I, Takeda J, Sano S. 2013

[雑誌論文] Clear association between serum levels of adipokines and T-helper 17-related cytokines in patients with psoriasis.

Nakajima H, Nakajima K, Tarutani M, Sano S. 2013

[雑誌論文] GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.

Tarutani M, Nakajima K, Uchida Y, Takaishi M, Goto-Inoue N, Ikawa M, Setou M, Kinoshita T, Elias PM, Sano S, Maeda Y 2012

[雑誌論文] Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells.

Yokogawa M, Takaishi M, Nakajima K, Kamijima R, Digiovanni J, Sano S. 2012

[図書] 乾癬の動物モデル(遺伝子改変マウス, 皮膚科臨床アセット10

佐野栄紀 2012

[雑誌論文] Topical tacrolimus treatment does not facilitate photocarcinogenesis incancer-prone mice.

Shiga T, Yokogawa M, Nakajima K, Kitagawa C, Tarutani M, Kumagai N, Sano S. 2012

[雑誌論文] Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804.

Miyoshi K, Takaishi M, Digiovanni J, Sano S. 2012

[学会発表] Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in K5.Stat3C transgenic mice

Sato K, Takaishi M, Tokuoka S, Sano S 2012

[雑誌論文] Sebaceous glands as the primary target of EGFR-inhibitors in the development of papulopustular eruption.

Takata T, Tarutani M, Zouboulis CC, Sano S. 2012

[雑誌論文] Positive link between STAT3 activation and Th17 cell infiltration to the lesional skin in vitiligo vulgaris.

Tanemura A, Kotobuki Y, Itoi S, Takata T, Sano S, Katayama I. 2012

[図書] 乾癬, 今日の治療指針2012年版(Vol54).

佐野栄紀 2012

[学会発表] 乾癬の新規治療法

佐野栄紀 2012

[雑誌論文] Stat3 as a therapeutic target for the treatment of psoriasis : a clinical feasibility study with STA-21, a Stat3 inhibitor.

Miyoshi K, Takaishi M, Nakajima K, Ikeda M, Kanda T, Tarutani M, Iiyama T, Asao N, DiGiovanni J, Sano S. 2011

[図書] 悪性内皮細胞腫, 瀧川雅浩他編, 皮膚疾患最新の治療2011-2012

佐野栄紀 2011

[雑誌論文] Altered lipid profiles in the stratum corneum of Sjogren-Larsson syndrome.

Nakajima K, Sano S, Uchida Y, Akiyama M, Morita Y, Shimizu H. 2011

[学会発表] IL-23 is essential, but IL-22 is dispensable for the development of psoriasis-like lesions in K5.

Takaishi M, Nakajima K, Ouyang W, Sano S. 2011

[学会発表] 乾癬マウスモデルにおけるIL-23依存性IL-22非依存性シグナルによる皮疹形成

高石 樹朗, 中島喜美子, Wenjun Ouyang, 佐野 栄紀. 2011

[雑誌論文] FDG PET/CT is a powerful tool for detecting subclinical arthritis in patients with psoriatic arthritis and/or psoriasis vulgaris.

Takata T, Taniguchi Y, Ohnishi T, Kohsaki S, Nogami M, Nakajima H, Kumon Y, Terada Y, Ogawa Y, Tarutani M, Sano S. 2011

[学会発表] Development of psoriasis-like lesions in a mouse model by IL-23-dependent but IL-22-independent.

Takaishi M, Nakajima K, Ouyang W, Sano S. 2011

[図書] 第4節乾癬モデル, 疾患モデルの作製と利用-免疫疾患

佐野栄紀 2011

[雑誌論文] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model.

Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S. 2011

[学会発表] Development of psoriasis-like lesions in a mouse model by IL-23-dependent but IL-22-independent signaling

Takaishi, M. 2011

[学会発表] 乾癬マウスモデルにおけるIL-23依存性IL-22非依存性シグナルによる皮疹形成

高石樹朗 2011

[学会発表] IL-23 is essential, but IL-22 is dispensable for the development of psoriasis-like lesions in K5.Stat3C mice

Takaishi, M. 2011

[学会発表] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model.

Nakajima K, Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Iwakura Y, DiGiovanni J, Sano S. 2010

[学会発表] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human keratinocyte derived cell lines.

Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S. 2010

[学会発表] Possible contribution of IL-22-producing non-T cells to the development of psoriasis-like lesion in a mouse model.

Nakajima K, Singa S, Kanda T, Takaishi M, Miyoshi K, Sano S. 2010

[学会発表] 乾癬におけるindirubinの有効性

三好研、高石樹朗、佐野栄紀 2010

[学会発表] 表皮特異的Golgi pH regulator欠損マウスのphenotype

樽谷勝仁、中島喜美子、高石樹朗、佐野栄紀、前田裕輔、木下タロウ 2010

[学会発表] Stat3阻害剤であるSTA-21はヒト正常表皮角化細胞とヒト角化細胞由来株細胞の分化を誘導する

高石樹朗、横川真紀、三好研、中島喜美子、John DiGiovanni、佐野栄紀 2010

[学会発表] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human, keratinocyte derived cell lines.

Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S. 2010

[学会発表] 日光角化症におけるイミキモドの抗腫瘍作用:モデルマウスを用いた解析

横川真紀、志賀建夫、高石樹朗、樽谷勝仁、佐野栄紀 2010

[学会発表] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model

Nakajima K. Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S. 2010

[学会発表] Stat3をターゲットとした新規乾癬治療法の開発

三好研、中島喜美子、高石樹朗、佐野栄紀 2010

[学会発表] Role of Smad-interacting protein 1 (SIP1) in collagen synthesis of dermal fibroblasts.

Teraishi M, Takaishi M, Ikeda M, Furukwa T, Shimoda S, Asada Y, Sano S. 2010

[図書] 魚鱗癬, 飯塚一編, 今日の治療指針2010年版 (Vol.52)

佐野栄紀 2010

[学会発表] 皮膚線維芽細胞のコラーゲン合成におけるSmad interacting protein 1(SIP1)の働き

寺石美香、高石樹朗、池田光徳、古川貴久、深田俊幸、下田信治、朝田芳信、佐野栄紀 2010

[学会発表] K5.Stat3トランスジェニックマウスに生じる乾癬様皮疹におけるPlasmacytoid dendritic cells(PDCs)の関与

高石 樹朗, 片岡 健, Kaoru Kiguchi, Michal Gilliet、佐野 栄紀、John Digiovanni. 2010

膠原病の病態モデル動物、当該病態モデル動物の作製方法、及び当該病態モデル動物のスクリーニング方法