トップ›研究者を探す›ストレス評価・うつ病予知をめざすRNAバイオロジー研究

ストレス評価・うつ病予知をめざすRNAバイオロジー研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-22390146
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
内科系臨床医学
内科学一般(含心身医学)
研究機関 徳島大学
代表研究者 六反 一仁
研究分担者 桑野 由紀
研究期間 開始年月日 2010/4/1
研究期間 終了年度 2012
研究ステータス 完了 (2012/4/1)
配分額（合計） 18,720,000 (直接経費 :14,400,000、間接経費 :4,320,000)
配分額（履歴） 2012年度：5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
2011年度：5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
2010年度：8,060,000 (直接経費 :6,200,000、間接経費 :1,860,000)
キーワード ストレス
うつ病
遺伝子発現
RNAマーカー
マイクロRNA

研究成果

[雑誌論文] Downregulation of serine/arginine-rich splicing factor 3 induces G1 cell cycle arrest and apoptosis in colon cancer cells

Kurokawa K, Akaike Y, Masuda K, Kuwano Y, Nishida K, Yamagishi N, Kajita K, Tanahashi T, Rokutan K 2013

[雑誌論文] Ets1 and heat shock factor 1 regulate transcription of the Transformer 2beta gene in human colon cancer cell

Kajita K, Kuwano Y, Kitamura N, Satake Y, Nishida K, Kurokawa K, Akaike Y, Honda M, Masuda K, Rokutan K 2013

[雑誌論文] Psychological Resources as Mediators of the Association Between Social Class and Health: Comparative Findings from Japan and the USA.

Kamezaki Y 2013

[雑誌論文] Chronic inhibition of tumor cell-derived VEGF enhances the malignant phenotype of colorectal cancer cells.

Yamagishi N, Teshima-Kondo S, Masuda K, Nishida K, Kuwano Y, Dang DT, Dang LH, Nikawa T, Rokutan K. 2013

[雑誌論文] Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells

Kurokawa K, Tanahashi T, Iima T, Yamamoto Y, Akaike Y, Nishida K, Masuda K, Kuwano Y, Murakami Y, Fukushima M, Rokutan 2012

[雑誌論文] Circulating vascular endothelial growth factor is independently and negatively associated with trait anxiety and depressive mood in healthy Japanese university students

Katsuura S, Kamezaki Y, Yamagishi N, Kuwano Y, Nishida K, Masuda K, Tanahashi T, Kawai T, Arisawa K, Rokutan K. 2012

[雑誌論文] Autism-associated gene expression in peripheral leucocytes commonly observed between subjects with autism and healthy women having autistic children

Kuwano Y, et al 2011

[雑誌論文] Skipping of an alternative intron in the srsf1 3' untranslated region increases transcript stabilit

Akaike Y, Kurokawa K, Kajita K, Kuwano Y, Masuda K, Nishida K, Wan Kang S, Tanahashi T, Rokutan K 2011

[学会発表] 遺伝子発現解析からみた慢性疲労症候群の病態

六反一仁 2011

[雑誌論文] Interleukin-18 deficiency reduces neuropeptide gene expressions in the mouse amygdala related with behavioral chang

Yamamoto Y, Tanahashi T, Katsuura S, Kurokawa K, Nishida K, Kuwano Y, Kawai T, Teshima-Kondo S, Chikahisa S, Tsuruo Y, Sei H, Rokutan K. 2010

[雑誌論文] Brief naturalistic stress induces an alternative splice variant of SMG-1 lacking exon 63 in peripheral leukocyte

Kurokawa K, Kuwano Y, Tominaga K, Kawai T, Katsuura S, Yamagishi N, Satake Y, Kajita K, Tanahashi T, Rokutan K 2010

[学会発表] The mechanism of transformer 2-□ gene expression in response to oxidative stress in human colon epithelial cells

Kazuhito Rokutan 2010

[雑誌論文] High-throughput screening of brief naturalistic stress-responsive cytokines in university students taking examinations

Katsuura S, Kamezaki Y, Tominaga K, Masuda K, Nishida K, Yamamoto Y, Takeo K, Yamagishi N, Tanahashi T, Kawai T, Rokutan K 2010

[学会発表] ストレスマーカーの現状

六反一仁 2010

[学会発表] 心と遺伝子を探るストレスゲノミクス研究

六反一仁 2010

[学会発表] Alternative splice variants of SMG-1 as a potential marker for brief naturalistic stressors peripheral leukocytes

Kazuhito Rokutan 2010

[学会発表] High-throughput screening of immunomodulators identifies VEGF as a potential biomarker for trait anxiety and depressive mood in healthy Japanese university students

Kazuhito Rokutan 2010

[学会発表] High-throughput screening of brief naturalistic stress-responsive cytokines in Japanese university students taking examinations

Kazuhito Rokutan 2010