トップ研究者を探すニューラルネットワーク形成障害を導く環境要因と候補遺伝子の機能解析

ニューラルネットワーク形成障害を導く環境要因と候補遺伝子の機能解析

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-21791036
研究種目 若手研究(B)
研究分野 生物系
医歯薬学
内科系臨床医学
胎児・新生児医学
研究機関 香川大学
代表研究者 松本 由樹
研究期間 開始年月日 2009/4/1
研究期間 終了年度 2010
研究ステータス 完了 (2010/4/1)
配分額(合計) 4,290,000 (直接経費 :3,300,000、間接経費 :990,000)
配分額(履歴) 2010年度:1,300,000 (直接経費 :1,000,000、間接経費 :300,000)
2009年度:2,990,000 (直接経費 :2,300,000、間接経費 :690,000)
キーワード ニューラルネットワーク
アルコール曝露動物
幹細胞性の保持
神経変性疾患
環境要因
迷走神経
ニューラルネットワーク形成障害
環境因子
細胞膜表面
シナプス膜
アルコール曝露
神経細胞
グリア細胞
細胞の脆弱性

研究成果

[学会発表] 体温調節能確立直後における寒冷刺激がもたらす消化吸収機能への影響

松本由樹, 他 2011

[学会発表] Neuronal transcytosis of WGA-amyloid beta complex in the rat

Yoshiki MATSUMOTO, et al. 2011

[学会発表] Morphmetric aspects of villous membrane structure in animal science.

Matsumoto Y, Takeuchi Y, Yamauchi KE. 2011

[雑誌論文] Yoshiki Takeuchi Revaluation of neuronal contacts with pituicytes in the rat posterior pituitary

Jun-Qian Liu, Takanori Miki, Katsuhiko Warita, Ken-ichi Ohta, Tomiko Yakura, Yoshiki Matsumoto 2011

[図書] Early Detection and Rehabilitation Technologies for Dementia: Neuroscience and Biomedical Applications, Chapter 21th, Neuronal transcytosis of WGA conjugated protein: a new approach to Amyloid-β in vivo,

Takeuchi Y, Matsumoto Y, Miki T, Warita K, Liu JQ. 2011

[学会発表] Neuronal transcytosis of WGA-amyloid beta complex in the rat.

Matsumoto Y, Liu JQ, Miki T, Warita K, Ohta K, Yakura T, Takeuchi Y. 2011

[雑誌論文] Nuclear Orphan Receptor TLX Induces Oct-3/4 for the Survival and Maintenance of Adult Hippocampal Progenitors upon Hypoxia.

Chavali PL, Saini RK, Matsumoto Y, Agren H, Funa K. 2011

[学会発表] Synaptic transcytosis of HRP-labbeled marker proteins.

Takeuchi Y, Miki T, Warita K, Ohta K, Yakura T, Liu JQ, Matsumoto Y. 2011

[雑誌論文] Effects of short-term ethanol ingestion on the expression of neurotrophins and the it receptors : No changes in the expression of the glial-derived neurotrophic factor in the mouse hippocampus.

Matsumoto Yoshiki 2010

[雑誌論文] Early postnatal ethanol exposure induces fluctuation in the expression of BDNF mRNA in the developing rat hippocampus.

Miki T, Kuma H, Yokoyama T, Sumitani K, Matsumoto Y, Kusaka T, Warita K, Wang ZY, Hosomi N, Imagawa T, S Bedi K, Itoh S, Nakamura Y, Takeuchi Y. 2010

[学会発表] Neuronal transcytosis of protein:application for Amyloid-β in vivo

Matsumoto Y, Miki T, Warita K, Takeuchi Y 2010

[雑誌論文] GABA expression in c-Fos immunoreactive neurons of the rat periaqueductal gray induced by electro-acu-pun-c-ture at the point of Zusanli.

Matsumoto Yoshiki 2010

[学会発表] 非小胞性シナプス輸送: WGA-HRPおよびRab3A-siRNAによる研究

Matsumoto Yoshiki 2010

[雑誌論文] TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors

Elmi M, Matsumoto Y, et al., Contributed equally. 2010

[雑誌論文] Modulation of the hypothalamopituitary axis in Mini rat: Further studies with hypophysiotropic somatostatin and gonadotroph cells.

Matsumoto Y 2010

[雑誌論文] Nerve growth factor and receptors are significantly affected by histamine stimulus through H1 receptor in pancreatic carcinoma cells.

Wang ZY, Ding Y, Miki T, Warita K, Matsumoto Y, Takeuchi Y, Wang SJ, Feng JG, Liu W, Wang YD, Wang XL, Wang YH, Liu Y, Shan BE. 2010

[学会発表] An approach for decrease of β-amyloid deposits in neuron.

Matsumoto Y, Miki T, Warita K, Yakura T, T.Liu JQ, Takeuchi Y. 2010

[雑誌論文] Short-term exposure to ethanol causes a differential response between nerve growth factor and brain-derived neurotrophic factor ligand/receptor systems in the mouse cerebellum.

Wang ZY, Miki T, Lee KY, Yokoyama T, Kusaka T, Sumitani K, Warita K, Matsumoto Y, Yakura T, Hosomi N, Ameno K, Bedi KS, Takeuchi Y. 2010

[雑誌論文] Modulation of the hypothalamopituitary axis in Mini rat : Further studies with hypophysiotropic somatostatin and gonadotroph cells

Matsumoto Y. 2010

[雑誌論文] Sharing first authorship.TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors.

Elmi M, Matsumoto Y, Zeng ZJ, Chavali PL, Yang W, Uemura A, Nishikawa S, Moshiri A, Tajima N, Agren H, Funa K. 2010

[学会発表] An approach for decrease of β-amyloid deposits in neuron

Yoshiki MATSUMOTO, et al. 2010

[学会発表] Neuronal transcytosis of protein : application for Amyloid-β in vivo

Yoshiki Matsumoto , et al. 2010

[雑誌論文] Effects of short-term ethanol ingestion on the expression of neurotrophins and their receptors: No changes in the expression of the glial-derived neurotrophic factor in the mouse hippocampus.

UenoT, Miki T, Wang ZY, Yokoyama T, Lee KY, Kusaka T, Warita K, Sumitani K, Matsumoto Y, Yakura T, Liu JQ, Bedi KS, Takeuchi Y. 2010

[雑誌論文] GABA expression in c-Fos immunoreactive neurons of the rat periaqueductal gray induced by electroacupuncture at the point of Zusanli.

Fusumada K, Yokoyama T, Miki T, Matsumoto Y, Warita K, Wang ZY, Yakura T, Liu JQ, Takeuchi Y. 2010

[雑誌論文] Anterograde synaptic transport of neuronal tracer enzyme (WGA-HRP) : Further studies with Rab3A-siRNA in rats.

Matsumoto Yoshiki 2009

[学会発表] A protein conjugation of WGA essential for transsynaptic tracer in neuronal system : application for Amyloid-βin vivo

Matsumoto Yoshiki 2009

[学会発表] Modulation of the hypothalamopituitary axis in Mini rat: Further studies with hypophysiotropic somatostatin and gonadotroph cells.

Matsumoto Y, Miki T, Tukamoto Y, Warita K, Wang ZY, Yakura T, Agren N, Karasawa S, Ueda S,Takeuchi Y. 2009

[学会発表] A protein conjugation of WGA essential for transsynaptic tracer in neuronal system: application for Amyloid-β in vivo.

Takeuchi Y, Matsumoto Y, Miki T, Warita K, Liu JQ. 2009

[雑誌論文] Short-term exposure to ethanol causes a differential response between nerve growth factor and brain-derived neurotrophic factor ligand/receptor systems in the mouse cerebellum.

Matsumoto Yoshiki 2009

[学会発表] Modulation of the hypothalamopituitary axis in Mini rat : Further studies with by pophysiotropic somatostatin and gonadotroph cells

Matsumoto Yoshiki 2009

[学会発表] WGA結合タンパクがもたらすシナプス膜輸送機構の新展開

松本由樹 2009

[学会発表] 体温調節能確立直後における寒冷刺激がもたらす消化吸収機能への影響

松本由樹、山内高圓

[雑誌論文] Anterograde synaptic transport of neuronal tracer enzyme (WGA-HRP): Further studies with Rab3A-siRNA in rats.

Takeuchi Y, Matsumoto Y, Miki T, Yokoyama T, Warita K, Wang ZY, Ueno T, Yakura T, Fujita M.