研究成果

[雑誌論文] Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model

Tagami, T., Abu Lila, A. S., Matsunaga, M., Moriyoshi, N., Nakamura, H., Nakamura, K., Suzuki, T., Doi, Y., Ishida, T., Kiwada, H. 2012

[雑誌論文] Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model : Synergy or antagonism?

Abu Lila, A. S., Okada, T., Doi, Y., Ichihara, M., Ishida, T., Kiwada, H. 2012

[学会発表] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開

石田竜弘 2012

[学会発表] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenviroment

Ishida, T., Kiwada, H. 2011

[図書] Cationic liposomes and tumour vasculature targeting : a therapeutic approach that has potential for solid tumours

Abu Lila A. S., Ishida T., Kiwada, H. 2011

[雑誌論文] A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA

Nakamura, K, Abu Lila A., Matsunaga, M., Doi, Y., Ishida, T., Kiwada, H. 2011

[学会発表] A novel double modulation strategy in cancer treatment with chemothera peutic agent and siRNA : S-1 improves siRNA accumulation and then Bcl-2 knockdown by the siRNA increases chemosensitivity of 5-FU.

Ishida, T. 2011

[学会発表] 腫瘍内微小環境変化を利用した核酸デリバリー戦略

石田竜弘 2011

[学会発表] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発

石田竜弘 2010

[雑誌論文] Sequential administration with oxaliplatin-containing PEG-coated cationic liposomes promotes a significant delivery of subsequent dose into murine solid tumor

Abu Lila, A., Doi, Y., Nakamura, K., Ishida, T., Kiwada, H. 2010

[学会発表] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発

石田竜弘、際田弘志 2010

[雑誌論文] Combination therapy of metronomic S-1 dosing with oxaliplatin-containing PEG-coated liposome improves antitumor activity in a murine colorectal tumor model

Doi Y., Okada T., Matsumoto H., Ichihara M., Ishida T., Kiwada, H. 2010

[学会発表] 生体内動態検討を基盤としたリポソームDDSの開発

石田竜弘 2010

[雑誌論文] Targeting anticancer drugs to tumor vasculature using cationic liposomes

Abu Lila, A., Ishida, T., Kiwada, H. 2010

[図書] Breaking the barriers to tumor-targeting via nanocarrier-based drug delivery to the tumor microenvironment

Doi, Y., Ishida, T., Kiwada, H. 2010

[学会発表] 腫瘍へのsiRNAデリバリーシステムの開発～効果と安全性の観点から～

石田竜弘 2010

[学会発表] 腫瘍へのsiRNAデリバリーシステムの開発～効果と安全性の観点から～

石田竜弘 2010

[雑誌論文] Recent advances in tumor vasculature targeting using liposomal drug delivery systems

Abu Lila, A., Ishida, T., Kiwada, H. 2009

[雑誌論文] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model.

Ishida, T. 2009

[雑誌論文] Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model

Abu Lila, A., Kizuki, S., Doi, Y., Suzuki, T., Ishida, T., Kiwada, H. 2009

[雑誌論文] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model

Ishida, T., Shiraga, E., Kiwada, H. 2009

[雑誌論文] Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model

Abu-Lila, A, Suzuki, T., Doi, Y., Ishida, T., Kiwada, H. 2009

[学会発表] Improvement of tumor-targeting therapy with nanocarriers by changing the tumor microenvironment

Ishida, T., Kiwada, H. 2009

[学会発表] Argonaute2標的siRNAリポプレックスを用いたがん治療戦略、学術シンポジウム4 RNAi医薬の展望. From Bench to Bedside-

石田竜弘、浅井知浩、奥直人、際田弘志 2009