トップ研究者を探す重症心不全患者の心機能回復を目指した補助人工心臓による心臓リハビリシステムの構築

重症心不全患者の心機能回復を目指した補助人工心臓による心臓リハビリシステムの構築

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-21249073
研究種目 基盤研究(A)
研究分野 生物系
医歯薬学
外科系臨床医学
胸部外科学
研究機関 東京大学
代表研究者 西村 隆
研究分担者 許 俊鋭
研究分担者 山崎 健二
研究分担者 巽 英介
研究分担者 小野 稔
研究分担者 五條 理志
研究期間 開始年月日 2009/4/1
研究期間 終了年度 2011
研究ステータス 完了 (2011/4/1)
配分額(合計) 44,460,000 (直接経費 :34,200,000、間接経費 :10,260,000)
配分額(履歴) 2011年度:13,650,000 (直接経費 :10,500,000、間接経費 :3,150,000)
2010年度:14,560,000 (直接経費 :11,200,000、間接経費 :3,360,000)
2009年度:16,250,000 (直接経費 :12,500,000、間接経費 :3,750,000)
キーワード 補助人工心臓
bridge to recovery
心臓リハビリテーション
心不全
心筋酸素消費量

研究成果

[雑誌論文] Coronary vascular resistance increases under fullbypasssupport of centrifugal pumps-relation between myocardial perfusion and ventricular workload during pump support

Ando M, Takewa Y, Nishimura T, et al 2012

[雑誌論文] What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation?Intracircuit back-flow analysis in a mock cirsulation model

Masahiko Ando, Takashi Nishimura, Yoshiaki Takewa, Daisuke Ogawa, Kenji Yamazaki, Koichi Kashiwa, Shunei Kyo, Minoru ONo, Yoshiyuki Taenaka, Eisuke Tatsumi 2011

[雑誌論文] A Novel Counterpulse Drive Mode of Continuous-flow Left Ventricular Assist Devices Can Minimize Intracircuit Backward Flow During Pump Weaning

Ando M, Nishimura T, etal. 2011

[学会発表] Durability and Hemocompatibility of Mera Monopivot Centrifugal Pump

Takashi T. 2011

[雑誌論文] Creating an ideal off-test mode for rotary left ventricular assist devices : Establishing a safe and appropriate weaning protocol after myocardial recovery

Ando M, Nishimura T, et al. 2011

[学会発表] 当院における補助人工心臓装着患者の在宅管理

西村隆, 他5名 2011

[雑誌論文] Age and Preoperative Total Bilirubin Level Can Stratify Prognosis After Extracorporeal Pulsatile Left Ventricular Assist Device Implantation

Taro Siga, Kouichiro Kinugawa, Masaru Hatano, Atsushi Yao, Takashi Nishimura, Miyoko Endo, Naoko Kato, Yasunobu Hirata, Syunei Kyo, Minoru Ono, Ryozo Nagai 2011

[学会発表] The continuous-flow LVAD with Native Heart Load Control System (NHLCS) for bridge to recovery could control myocardial consumption of oxygen in acute heart failure model

Nishimura T, et al. 2011

[雑誌論文] Electrocardiogram-Synchronized Rotaional Speed Change Mode in Rotary Pumps Could Improve Pulatility

Masahiko Ando, Takashi Nishimura, Kenji Yamazaki, Shunei Kyo, Minoru Ono, Tomonori Tsukiya, Toshihide Muzuno, Yoshiyuki Taenaka, Eisuke Tatsumi 2011

[雑誌論文] A novel counerpulse drive mode of continuous-flow left ventricular assist devices can minimize intrciucuit backward flow suring pump weaning

Masahiko Ando, Takashi Nishimura, Yoshiaki Takewa, Daisuke Ogawa, Kenji Yamazaki, Koichi Kashiwa, Shunei Kyo, Minoru Ono, Yoshiyuki Taenaka, Eisuke Tatsumi 2011

[学会発表] Current Therapy with VAD for Severe Heart Failure Patients in Japan

Takashi Nishimura 2011

[雑誌論文] Less Frequent Opening of the Aortic Valve and a Continuous Flow Pump Are Risk Factors for Postoperative Onset of Aortic Insufficiency in Patients With a Left Ventricular Assist Device

Masaru Hatano, Koichiro Kinugawa, Taro Shiga, Naoko Kato, Miyoko Endo, Motoyuki Hisagi, Takashi Nishimura, Atsushi Yao, Yasunobu Hirata, Shunei Kyo, Minoru Ono, Ryozo Nagai 2011

[雑誌論文] What is the ideal off-test yrial for continuous-flow ventricular assist device explantation?-Intracircuit back flow analysis in a mock circulatory circulation

Ando M, Nishimura T, etal. 2011

[雑誌論文] Negative pressure wound therapy for left ventricular assist device-related mediastinitis : two case reports

M.Kawata, T.Nishimura, Y.Hoshino, O.Kinoshita, M.Hisagi, M.Ando, T.Morota, N.Motomura, S.Kyo, M.Ono 2011

[雑誌論文] Alteration of LV end-diastolic volume by controlling the power of the continuous-flow LVAD, so it is synchronized with cardiac beat : development of a native heart load control system (NHLCS)

Umeki A, Nishimura T, et al. 2011

[雑誌論文] Successful treatment of mediastinitis after ventricular assist device implantation with rerouting of outflow vascular prosthesis

Chitaru Kurihara, Takashi Nishimura, Osamu KInoshita, Mitsuhiro Kawata, Motoyuki Hisagi, Shunei Kyo, Minoru Ono 2011

[雑誌論文] Electrocardiogram-synchronized rotational speed change mode in rotary pupscould improve pulsatility

Ando M, Nishimura T, etal. 2011

[学会発表] The continuous-flow LVAD with Native Heart Load Control System(NHLCS) for bridge to recovery could control myocardial consumption of oxygen in acute heart failure model

Nishimura T. 2011

[学会発表] Development of Native Heart Load Control System with Continuous Flow Ventricular Assist Device for Bridge to Recovery

Nishimura T, etal. 2010

[雑誌論文] Triple-site pacing : a new supported therapy approach for bridge to recovery with a left ventricular assist system in a patient with idiopathic dilated cardiomyopathy

Nishimura T, Kyo S 2010

[学会発表] 自己心機能回復を目指した定常流型補助人工心臓コントロールシステムの開発

西村隆, 他6名 2010

[雑誌論文] Vacuum-assisted closure with Safetec technology for mediastinitis in patients with a ventricular assist device

Kinoshita O, Nishimura T, et.al. 2010

[雑誌論文] High-dose carvedilol therapy for mechanical circulatory assisted patients

Nishimura T, Kyo S 2010