トップ研究者を探す糖鎖関連分子を標的にした生活習慣病予防マーカーの開発

糖鎖関連分子を標的にした生活習慣病予防マーカーの開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-21249038
研究種目 基盤研究(A)
研究分野 生物系
医歯薬学
境界医学
病態検査学
研究機関 大阪大学
代表研究者 三善 英知
研究分担者 寶學 英隆
研究分担者 中村 祐
研究分担者 新崎 信一郎
研究分担者 鎌田 佳宏
研究期間 開始年月日 2009/4/1
研究期間 終了年度 2013
研究ステータス 完了 (2013/4/1)
配分額(合計) 45,760,000 (直接経費 :35,200,000、間接経費 :10,560,000)
配分額(履歴) 2013年度:5,980,000 (直接経費 :4,600,000、間接経費 :1,380,000)
2012年度:7,280,000 (直接経費 :5,600,000、間接経費 :1,680,000)
2011年度:7,020,000 (直接経費 :5,400,000、間接経費 :1,620,000)
2010年度:7,670,000 (直接経費 :5,900,000、間接経費 :1,770,000)
2009年度:17,810,000 (直接経費 :13,700,000、間接経費 :4,110,000)
キーワード 糖鎖
生活習慣病
予防マーカー
レクチン
IgG
脂肪肝
皮膚
ELISA
データベース

研究成果

[雑誌論文] Efficacy and safety of memantine in patients with moderate-to-severe Alzheimer's disease : results of a pooled analysis of two randomized, double-blind, placebo-controlled trials in Japan

Nakamura Y, Matsui D. et al 2014

[雑誌論文] A patient with type II citrullinemia who developed refractory complex seizure

Sakamoto S, Nakamura Y. et al 2013

[雑誌論文] The threshold of pentylenetetrazole-induced convulsive seizures, but not that of nonconvulsive seizures, is controlled by the nitric oxide levels in murine brains

Watanabe Nakamura Y, Itoh K. et al 2013

[雑誌論文] Ethanol- and acetaldehyde-induced cholinergic imbalance in the hippocampus of Aldh2-knockout mice does not affect nerve growth factor or brain-derived neurotrophic factor

Jamal M, Nakamura Y, Kinoshita H. et al 2013

[雑誌論文] Low-dose nicotine facilitates spatial memory in ApoE-knockout mice in the radial arm maze

Sultana R, Ameno K, JNakamura Y. et al 2013

[雑誌論文] A patient with type II citrullinemia who developed refractory complex seizure. Gen Hosp Psychiatry.

Sakamoto S, Nakamura Y, et al. 2013

[雑誌論文] Pentylentetrazole-induced loss of blood-brain barrier integrity involves excess nitric oxide generation by neuronal nitric oxide synthase

Danjo S, Nakamura Y, Itoh K. et al 2013

[雑誌論文] CIBIC Plus-J Assessment Using a Videotaped Method in Alzheimer's.

Nakamura Y, et al. 2012

[雑誌論文] High ethanol and acetaldehyde impair spatial memory in mouse models : opposite effects of aldehyde dehydrogenase 2 and apolipoprotein E on memory

Jamal M, Nakamura Y, Kinoshita H. et al 2012

[雑誌論文] Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats

Hama S, INakamura Y, Itoh K. et al 2012

[雑誌論文] Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats.

Nakamura Y, Itoh K, et al. 2012

[雑誌論文] CIBIC Plus-J Assessment Using a Videotaped Method in Alzheimer's Disease

Nakamura Y, Homma A. et al 2012

[雑誌論文] A 24-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and tolerability of the rivastigmine patch in Japanese patients with Alzheimer's disease

Nakamura Y, Imai Y, Homma A. et al 2011

[雑誌論文] Effect of levothyroxine on prolonged nocturnal sleep time and excessive daytime somnolence in patients with idiopathic hypersomnia

Shinno H, Nakamura Y. et al 2011

[雑誌論文] Does the Use of Nursing-Care Services Reduce the Information about Dementia Patients Provided by Their Caregivers?

Nakamura Y, Homma A 2011

[雑誌論文] Successful treatment of restless legs syndrome with the herbal prescription Yokukansan.

Shinno H, Nakamura Y, Inami Y, Horiguchi J., et al. 2010

[雑誌論文] Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome

Shinno H, Nakamura Y, Horiguchi J. et al 2010

[雑誌論文] Successful treatment with levothyroxine for idiopathic hypersomnia patients with subclinical hypothyroidism.

Shinno H, Nakamura Y, Horiguchi J, et al. 2010

[雑誌論文] Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome.

Shinno H, Nakamura Y, Horiguchi J, et al. 2010

[雑誌論文] Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome.

Shinno H, Nakamura Y, Horiguchi J, et al. 2010

[雑誌論文] Three patients with cancer who developed rapid-eye-movement sleep behavior disorder

Shinno H, Kamei M, Nakamura Y. et al 2010

[雑誌論文] Three patients with cancer who developed rapid-eye-movement sleep behavior disorder.

Shinno H, Horiguchi J, Nakamura Y., et al 2010

[雑誌論文] Successful treatment with levothyroxine for idiopathic hypersomnia patients with subclinical hypothyroidism

Shinno H, Nakamura Y, Horiguchi J. et al 2009