トップ研究者を探す脱髄性疾患に対する統合的定量ミエリンイメージングの開発

脱髄性疾患に対する統合的定量ミエリンイメージングの開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-20K07997
研究種目 基盤研究(C)
研究分野
研究機関 徳島大学
代表研究者 金澤 裕樹
研究期間 開始年月日 2020/4/1
研究期間 終了年度 2022
研究ステータス 完了 (2022/4/1)
配分額(合計) 4,420,000 (直接経費 :3,400,000、間接経費 :1,020,000)
配分額(履歴) 2022年度:520,000 (直接経費 :400,000、間接経費 :120,000)
2021年度:650,000 (直接経費 :500,000、間接経費 :150,000)
2020年度:3,250,000 (直接経費 :2,500,000、間接経費 :750,000)
キーワード 磁気共鳴画像(MRI)
髄鞘(ミエリン)
緩和時間
磁化率
拡散係数
磁化移動
機械学習
ミエリン
MRI
MWF
MT
DKI
VBM
SVM

研究成果

[雑誌論文] Quantitative parameter mapping of contrast agent concentration and relaxivity and brain tumor extracellular pH

Matsumoto Yuki、Harada Masafumi、Kanazawa Yuki、Taniguchi Yo、Ono Masaharu、Bito Yoshitaka 2022

[学会発表] Conversion map from quantitative parameter mapping to myelin water fraction

Shun Kitano, Yuki Kanazawa, Masafumi Harada, Yo Taniguchi, Yuki Matsumoto, Hiroaki Hayashi, Kosuke Ito, Yoshitaka Bito and Akihiro Haga 2022

[学会発表] Evaluation of Blood Flow and Plaque Vulnerability in Carotid Artery Stenosis Focusing on Morphological and Component Characteristics

Yuki Matsumoto, Yuki Kanazawa, Yuki Kinjo, Masafumi Harada, Toshiaki Miyati, Hiroaki Hayashi, Mitsuharu Miyoshi, Naoki Maeda, Yasuhisa Kanematsu, Yasushi Takagi and Akihiro Haga 2022

[学会発表] Evaluation of brain tumor and surrounding tissue activity using multi-pool CEST imaging on 3 Tesla scanner

Yuki Kanazawa, Masafumi Harada, Mitsuharu Miyoshi and Yuki Matsumoto 2022

[雑誌論文] Editorial for “Chemical Exchange Saturation Transfer (CEST) MRI for Differentiating Radiation Necrosis from Tumor Progression in Brain Metastasis: Application in a Clinical Setting”

Kanazawa Yuki、Harada Masafumi 2022

[学会発表] Development of self-calibrating B1 correction for three-dimensional variable flip angle T1 mapping

Nagomi Fukuda, Yuki Kanazawa, Hiroaki Hayashi, Yuki Matsumoto, Masafumi Harada, Motoharu Sasaki and Akihiro Haga 2022

[雑誌論文] Myelin-weighted imaging derived from quantitative parameter mapping

Kanazawa Yuki、Harada Masafumi、Taniguchi Yo、Hayashi Hiroaki、Abe Takashi、Otomo Maki、Matsumoto Yuki、Ono Masaharu、Ito Kosuke、Bito Yoshitaka、Haga Akihiro 2022

[学会発表] Determination of Alzheimer's disease based on morphology and atrophy using machine learning combined with automated segmentation

Natsuki Ikemitsu, Yuki Kanazawa, Akihiro Haga, Hiroaki Hayashi, Yuki Matsumoto and Masafumi Harada 2022

[学会発表] Is It Possible to Evaluate Morphological Carotid Artery Stenosis Information Using NASCET Criteria?

Naoki Maeda, Yuki Kanazawa, Yuki Kinjo, Yuki Matsumoto, Masafumi Harada, Tosiaki Miyati, Hiroaki Hayashi, Mitsuharu Miyoshi, Yasuhisa Kanematsu, Yasushi Takagi, and Akihiro Haga 2021

[学会発表] Derivation of Water Exchange Constants between Components using Quantitative Parameter Mapping (QPM)

Naoki Maeda, Yuki Kanazawa, Masafumi Harada, Yo Taniguchi, Yuki Matsumoto, Hiroaki Hayashi, Kosuke Ito, Yoshitaka Bito and Akihiro Haga 2021

[学会発表] What Is The Extracellular pH Of Brain Tumors And How Can We Detect Brain Tumors Using Gadolinium-based-contrast Agents?

Yuki Matsumoto, Masafumi Harada, Yuki Kanazawa, Taniguchi Yo, Ono Masaharu and Bito Yoshitaka 2021

[学会発表] Brain Tumor Characterization and Assessment using Automatic Detection of Extracellular pH Change

Yuki Matsumoto, Masafumi Harada, Yuki Kanazawa, Yo Taniguchi, Masaharu Ono and Yoshitaka Bito 2021

[学会発表] Myelin imaging derived quantitative parameter mapping compared to myelin water fraction

Yuki Kanazawa, Masafumi Harada, Yo Taniguchi, Syun Kitano, Nagomi Fukuda, Yuki Matsumoto, Hiroaki Hayashi, Kosuke Ito, Yoshitaka Bito and Akihiro Haga 2021

[雑誌論文] Quantitative analysis of vibration waves based on Fourier transform in magnetic resonance elastography

Kosaka Ikuho、Kanazawa Yuki、Baba Kotaro、Hayashi Hiroaki、Harada Masafumi 2020

[雑誌論文] Reproducibility and Variability of Quantitative Cerebral Blood Flow Measured by Multi-delay 3D Arterial Spin Labeling According to Sex and Menstrual Cycle

Otomo Maki、Harada Masafumi、Abe Takashi、Matsumoto Yuki、Abe Yumi、Kanazawa Yuki、Miyoshi Mitsuharu、Kabasawa Hiroyuki、Takahashi Yoshitake 2020

[学会発表] Characterization of Brain Tumors using Amide Proton and Nuclear Overhauser Effect at 3 Tesla MR Scanner

Yuki Kanazawa, Masafumi Harada, Mitsuharu Miyoshi, Takashi Abe, Yuki Matsumoto and Yasushi Takagi 2020

[学会発表] Chemical Exchange Saturation Transfer Imaging for Atherosclerotic Plaques

Yuki Kanazawa, Masafumi Harada, Tosiaki Miyati, Takashi Abe, Mitsuharu Miyoshi, Yuki Matsumoto, Hiroaki Hayashi, Yasuhisa Kanematsu and Yasushi Takagi 2020

[学会発表] Calculation of Concentration of Contrast Media, Relaxivity, Extracellular pH and Oxygen Extraction Fraction for Brain Tumor Characterization

Yuki Matsumoto, Masafumi Harada, Yuki Kanazawa, Takashi Abe, Maki Ohtomo, Taniguchi Yo, Ono Masaharu and Bito Yoshitaka 2020