サイトカインシグナル伝達抑制分子(SOCS)の癌治療への応用

トップ›研究者を探す›サイトカインシグナル伝達抑制分子(SOCS)の癌治療への応用

代表研究者	世良田聡
研究課題番号	KAKENHI-PROJECT-20890302
研究種目	若手研究(スタートアップ)
研究分野	生物系医歯薬学外科系臨床医学泌尿器科学
研究機関	医薬基盤研究所
研究期間開始年月日	2008/4/1
研究期間終了年度	2009
研究ステータス	完了 (2009/4/1)
配分額（合計）	3,302,000 (直接経費 :2,540,000、間接経費 :762,000)
配分額（履歴）	2009年度：1,560,000 (直接経費 :1,200,000、間接経費 :360,000) 2008年度：1,742,000 (直接経費 :1,340,000、間接経費 :402,000)
キーワード	サイトカイン SOCS 癌

研究成果

[雑誌論文] iTRAQ-based proteomic identification of leucine rich alpha 2 glycoprotein(LRG)as a novel inflammatory biomarker in autoimmune diseases

Serada S 2010

[学会発表] Anti-proliferative effect of SOCS-1, -3 through the suppression of JAK/STAT and P38 MAPK signaling pathways in gastric cancer cells

Souma Y, Serada S, Naka T., et al (7人中4番目) 2009

[雑誌論文] iTRAQ-based proteomic identification of leucine rich alpha 2 glycoprotein (LRG) as a novel inflammatory biomarker in autoimmune diseases

Serada S, Naka T, et al.(13人中1番目) 2009

[学会発表] Megakaryocyte potentiating factor is a more effective marker for the differential diagnosis of malignant pleural mesothelioma compared with mesothelin.

Serada S 2009

[雑誌論文] Enhanced expression of Annexin A4 in clear cell carcinoma of the ovary and its association with chemoresistance to carboplatin

Kim A, Enomoto T, Serada S, Naka T, et al.(13人中3番目) 2009

[学会発表] Proteomics-based identification of leucine rich alpha 2 glycoprotein(LRG)as a novel biomarker associated with disease activity of inflammatory autoimmune disorders

Serada S 2009

[学会発表] SOCS-3 protein exhibits potent anti-tumor activity in malignant pleural mesothelioma

Iwahori K, Serada S, Naka T., et al (5人中2番目) 2009

[雑誌論文] IL-6 blockade inhibits the induction of myelin antigen specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

Serada S, Fujimoto M, Kishimoto T, Naka T, et al.(15人中1番目) 2008

[学会発表] Identification of alpha-enolase autoantibody as a novel biomarker in non-small cell lung cancer

Serada S 2008

[雑誌論文] Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

Fujimoto M, Serada S, Naka T, et al.(13人中3番目) 2008

[雑誌論文] IL-6 blockade inhibits the induction of myelin antigen specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

Serada S 2008

[雑誌論文] Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: Evaluation in comparison with mesothelin

Iwahori K, Osaki T, Serada S, Fujimoto M, Naka T, et al.(16人中3番目) 2008

[雑誌論文] Suppressor of cytokine signaling-1 ameliorates dextran sulfate sodium-induced colitis in mice

Horino J, Fujimoto M, Terabe F, Serada S, Kishimoto T, Naka T, et al.(14人中4番目) 2008

[雑誌論文] Aberrant Expression of Glycosylation in Juvenile Gastrointestinal Stromal Tumors

Takahashi T, Naka T, Fujimoto M, Serada S, Nishida T, et al.(14人中4番目) 2008

[雑誌論文]

世良田聡 2008

[雑誌論文] ranscriptional Complex Formation of c-Fos, STAT3, and HNF-1a is Essential for Cytokine-Driven CRP Gene Expression

Nishikawa T, Hagihara K, Serada S, Naka T, Yoshizaki K, et al.(10人中3番目) 2008

[学会発表] Proteomics-based identification of leucine rich alpha 2 glycoprotein (LRG) as a novel biomarker associated with disease activity of inflammatory autoimmune disorders

Serada S, Naka T., et al (6人中1番目)