研究成果

[雑誌論文] The ARNT-STAT3 axis regulates the differentiation of intestinal intraepithelial TCRαβ+CD8αα+cells

Nakajima K, Maekawa Y, KataokaK, IshifuneC, NishidaJ, ArimochiH, KitamuraA, YoshimotoT, TomitaS, NagahiroS, Yasutomo K 2013

[雑誌論文] Notch2 regulates the development of marginal zone B cells through Fos

Iwahashi S, Maekawa Y, Nishida J, Ishifune C, Kitamura A, Arimochi H, Kataoko K, Chiba S, Shimada M, Yasutomo K 2012

[雑誌論文] Dll4-Fc, an inhibitor of Dll4-Notch signaling, suppresses liver metastasis of small cell lung cancer cells through the downregulation of the NF-kappa-B activity.

Kuramoto T, Goto H, Mitsuhashi A, Tabata S, Ogawa H, Uehara H, Sijo A, Kakiuchi S, Maekawa, Yasutomo K, Hanibuchi M, Akiyama SI, Sone S, Nishioka Y 2012

[雑誌論文] Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice

ian G, Arimochi H, Kitamura A, Nishida J, Li S, Kishihara K, Maekawa Y, Yasutomo K 2012

[学会発表] 免疫プロテアソーム機能異常による炎症応答の分子基盤

安友康二 2012

[学会発表] Notch provides metabolic signals in memory CD4+ T cells

Koji Yasutomo 2012

[雑誌論文] Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine

Sakata-Yanagimoto M, Sakai T, Miyake Y, Saito T, Maruyama H, Morishita Y, Nakagami-Yamaguchi E, Kumano K, Yagita H, Fukayama M, Ogawa S, Kurokawa M, Yasutomo K, Chiba S 2011

[雑誌論文] Low-dose lipopolysaccharide affects lung allergic responses by regulating Jagged1 expression on antigen-pulsed dendritic Cells.

Okamoto M, Takeda K, Lucas JJ, Joetham A, Yasutomo K, Gelfand EW 2011

[雑誌論文] A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans

Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K. 2011

[学会発表] Notchシグナルによるリンパ球機能制御

安友康二 2010

[雑誌論文] Notch2 signaling is required for potent anti-tumor immunity in vivo

Sugimoto K, Maekawa Y, Kitamura A, Nishida J, Koyanagi A, Yagita H, Kojima H, Chiba S, Shimada M, Yasutomo K 2010

[雑誌論文] Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor.

Alam MS, Maekawa Y, Kitamura A, Tanigaki K, Yoshimoto T, Kishihara K, Yasutomo K 2010

[雑誌論文] Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese

Nishimoto K, Kochi Y, Ikari K, Yamamoto K, Suzuki A, Shimane K, Nakamura Y, Yano K, Iikuni N, Tsukahara S, Kamatani N, Okamoto H, Kaneko H, Kawaguchi Y, Hara M, Toyama Y, Horiuchi T, Tao K, Yasutomo K, Hamada D, Yasui N, Inoue H, Itakura M, Yamanaka H, Mo 2010

[雑誌論文] Notch activation induces the generation of functional natural killer cells from human cord blood CD34-positive cells devoid of interleukin-15.

Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S. 2009

[雑誌論文] Jagged1 suppresses collagen-induced arthritis by indirectly providing a negative signal in CD8+ T cells.

Kijima M, Iwata A, Maekawa Y, Uehara H, Izumi K, Kitamura A, Yagita H, Chiba S, Shiota H, Yasutomo K 2009

[雑誌論文] Gelfand EW. Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production.

Okamoto M, Matsuda H, Lucas JL, Domenico J, Yasutomo K, Takeda K 2009

[学会発表] Notch signaling controls T cell cytotoxicity

安友康二 2009

[学会発表] Notchシグナルによる免疫制御

安友康二 2008

[雑誌論文] Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.

Maekawa Y, Minato Y, Ishifune C, Kurihara T, Kitamura A, Kojima H, Yagita H, Sakata-Yanagimoto M, Saito T, Taniuchi I, Chiba S, Sone S, Yasutomo K 2005