研究成果

[雑誌論文] Preferential Accumulation of Activated Th1 Cells Not Only in Rheumatoid Arthritis But Also in Osteoarthritis Joints.

Yamada H, Nakashima Y, Okazaki K,Mawatari T, Fukushi JI, Oyamada A, Fujimura K, Iwamoto Y, Yoshikai Y. 2011

[雑誌論文] IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer.

Takeuchi A, Dejima T, Yamada H, Shibata K, Nakamura R, Eto M, Nakatani T, Naito S, Yoshikai Y. 2011

[雑誌論文] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.

Nakamura R, Maeda N, Shibata K, Yamada H, Kase T, Yoshikai Y. 2010

[学会発表] Tyk2 is indispensable for the development of experimental autoimmune disease

A.Oyamada, Y.Yoshikai, H.Yamada 2010

[学会発表] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury

R.Nakamura, N.Maeda, O.Noyori, K.Shibata, H.Yamada, Y.Yoshikai 2010

[雑誌論文] Antibody-mediated T-cell reduction or increased levels of chimerism overcome resistance to cyclophosphamide-induced tolerance in NKT-deficient mice.

Onzuka T, Tomita Y, Okano S, Shimizu I, Yamada H, Yoshikai Y, Tominaga R. 2010

[雑誌論文] CD30 Ligand Is a Target for a Novel Biological Therapy against Colitis Associated with Th17 Responses

Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y. 2010

[雑誌論文] CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice.

Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y. 2010

[学会発表] マウスコラーゲン誘導性関節炎におけるTyk2の重要性

小山田亜希子、藤村謙次郎、岩本幸英、吉開泰信、山田久方 2010

[学会発表] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.

R.Nakamura, N.Maeda, O.Noyori, K.Shibata, H.Yamada, Y.Yoshikai 2010

[学会発表] Preferential accumulation of Th1 cells in the joints of rheumatoid arthritis and osteoarthritis

H.Yamada, A.Oyamada, Y.Yoshikai 2010

[雑誌論文] Current perspectives on the role of IL-17 in autoimmune disease

Yamada H 2010

[雑誌論文] The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury.

Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S. 2010

[雑誌論文] CD30 Ligand Is a Target for a Novel Biological Therapy against Colitis Associated with Th17 Responses.

Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Iwakura Y, Yoshikai Y. 2010

[雑誌論文] Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, Ishikawa T, Hoshino K, Uruno T, Cao Q, Higashi S, Kawaguchi Y, Enjoji M, Takayanagi R, Kaisho T, Yoshikai Y, Fukui Y. 2010

[雑誌論文] IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guerin treatment against bladder cancer.

Takeuchi A, Dejima T, Yamada H, Shibata K, Nakamura R, Eto M, Nakatani T, Naito S, Yoshikai Y. 2010

[雑誌論文] Current perspectives on the role of IL-17 in autoimmune disease.

Yamada H. 2010

[学会発表] The basic helix-loop-helix protein HES1は自然発生IL-17産生γδT細胞分化に必要である

柴田健輔、山田久方、吉開泰信 2010

[雑誌論文] The LTB4-BLT1 Axis Mediates Neutrophil Infiltration and Secondary Injury in Experimental Spinal Cord Injury.

Saiwai H, Ohkawa Y, Yamada H, Kumamaru H, Harada A, Okano H, Yokomizo T, Iwamoto Y, Okada S. 2010

[雑誌論文] Interleukin-15 is critical in the pathogenesis of influenza A virus-induced acute lung injury.

Nakamura R, Maeda N, Shibata K, Yamada H, Kase T, Yoshikai Y. 2010

[雑誌論文] Th17 cells and human arthritic diseases.

Yamada H. 2010

[雑誌論文] CD30 ligand/CD30 plays a critical role in Th17 differentiation in mice.

Sun X, Yamada H, Shibata K, Muta H, Tani K, Podack ER, Yoshikai Y. 2010

[学会発表] Preferential accumulation of Th1 cells in the joints of rheumatoid arthritis and osteoarthritis.

H.Yamada, A.Oyamada, Y.Yoshikai 2010

[雑誌論文] Mechanism of Synergistic Antitumor Effect of Sorafenib and Interferon-α on Treatment of Renal Cell Carcinoma

Takeuchi A, Eto M, Tatsugami K, Yamada H, Oki T, Kiyoshima K, Yoshikai Y, Naito S. 2010

[学会発表] IL-15は自己抗原特異的CD8陽性T細胞の維持と自然免疫機能に重要である

山田久方、逸見百江、吉開泰信 2009

[雑誌論文] IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guerin infection.

Tang C, Yamada H, Shibata K, Yoshida SI, Wajjwalku W, Yoshikai Y. 2009

[雑誌論文] Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice.

Ishikawa T, Yamada H, Oyamada A, Goshima F, Nishiyama Y, Yoshikai Y. 2009

[雑誌論文] Donor CD4 T Cells Are Critical in Allogeneic Stem Cell Transplantation against Murine Solid Tumor.

Kamiryo Y, Eto M, Yamada H, Yajima T, Harano M, Takeuchi A, Tatsugami K, Hamaguchi M, Naito S, Yoshikai Y. 2009

[学会発表] 関節リウマチの関節内CD4T細胞サブセットの解析

山田久方、中島康晴、岡崎賢、馬渡太郎、福士純一、小山田亜希子、岩本幸英 2009

[学会発表] ヒト関節リウマチとTh17細胞

山田久方 2009

[雑誌論文] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis

Oyamada A, Ikebe H, Itsumi M, Saiwai H, Okada S, Shimoda K, Iwakura Y, Nakayama K, Iwamoto Y, Yoshikai Y, Yamada H 2009

[雑誌論文] Direct recognition of mycobacterial cord factor, trehalose dimycolate, by C-type lectin Mincle

Ishikawa E, Ishikawa T, Morita Y, Toyonaga K, Yamada H, Takeuchi O, Akira S, Kinoshita T, Yoshikai Y, Yamasaki S 2009

[雑誌論文] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.

Oyamada A, Ikebe H, Itsumi M, Saiwai H, Okada S, Shimoda K, Iwakura Y, Nakayama K, Iwamoto Y, Yoshikai Y, Yamada H. 2009

[雑誌論文] Donor CD4 T Cells Are Critical in Allogeneic Stem Cell Transplantation against Murine Solid Tumor

Kamiryo Y, Eto M, Yamada H, Yajima T, Harano M, Takeuchi A, Tatsugami K, Hamaguchi M, Naito S, Yoshikai Y. 2009

[雑誌論文] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 4.

Takeuchi A, Kamiryou Y, Yamada H, Eto M, Shibata K, Haruna K, Naito S, Yoshikai Y. 2009

[雑誌論文] IL-15 protects antigen-specific CD8+ T cell contraction after Mycobacterium bovis bacillus Calmette-Guerin infection

Tang C, Yamada H, Shibata K, Yoshida SI, Wajjwalku W, Yoshikai Y. 2009

[雑誌論文] Direct recognition of mycobacterial cord factor, trehalose dimycolate, by C-type lectin Mincle.

Ishikawa E, Ishikawa T, Morita Y, Toyonaga K, Yamada H, Takeuchi O, Akira S, Kinoshita T, Yoshikai Y. Yamasaki S. 2009

[雑誌論文] IL-15 is critical for the maintenance and innate functions of self-specific CD8(+) T cells.

Itsumi M, Yoshikai Y, Yamada H. 2009

[雑誌論文] IL-15 is critical for the maintenance and innate functions of self-specific CD8(+)T cells

Itsumi M, Yoshikai Y, Yamada H. 2009

[雑誌論文] Effects of lipopolysaccharide on the induction of mixed chimerism in cyclophosphamide-induced tolerance

Onzuka T, Tomita Y, Shimizu I, Okano S, Yamada H, Yoshikai Y, Tominaga R. 2009

[雑誌論文] Th17 cells in human rheumatoid arthritis.

Yamada H. 2009

[雑誌論文] Protective role of Fas-FasL signaling in lethal infection with herpes simplex virus type 2 in mice

Ishikawa T, Yamada H, Oyamada A, Goshima F, Nishiyama Y, Yoshikai Y. 2009

[学会発表] IL-15は自己抗原特異的CD8T細胞の維持や機能を制御する

逸見百江、吉開泰信、山田久方 2009

[雑誌論文] Oral administration of xanthan gum enhances antitumor activity through Toll-like receptor 4

Takeuchi A, Kamiryou Y, Yamada H, Eto M, Shibata K, Haruna K, Naito S, Yoshikai Y. 2009

[雑誌論文] A novel role of CD30L/CD30 signaling by T-T cell interaction in Th1 response against mycobacterial infection.

Tang C, Yamada H, Shibata K, Muta H, Wajjwalku W, Podack ER, Yoshikai Y. 2008

[雑誌論文] Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells.

Nakamura R, Shibata K, Yamada H, Shimoda K, Nakayama K, Yoshikai Y. 2008

[雑誌論文] The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yoshikai Y, Inoue J, Akiyama T, Takahama Y. 2008

[雑誌論文] Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis.

Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y. 2008

[雑誌論文] Identification of CD25+ gammadelta T cells as fetal thymus-derived naturally occurring IL-17 producers.

Shibata K, Yamada H, Nakamura R, Sun X, Itsumi M, Yoshikai Y. 2008

[学会発表] 自己抗原特異的メモリー型T細胞の骨髄由来細胞による正の選択

山田久方、逸見百江、吉開泰信 2008

[雑誌論文] Comparative histopathological analysis between tenosynovitis and joint synovitis in rheumatoid arthritis.

Kaibara N, Yamada H, Shuto T, Nakashima Y, Okazaki K, Miyahara H, Esaki Y, Hirata G, Iwamoto Y 2008

[雑誌論文] Comparative histopathological analysis between tenosynovitis and joint synovitis in rheumatoid arthritis.

Kaibara N, Yamada H, Shuto T, Nakashima Y, Okazaki K, Miyahara H, Esaki Y, Hirata G, Iwamoto Y. 2008

[学会発表] IL-15 is critical to the development and functions of self-specific memory phenotype CD8 T cells

Momoe Itsumi, Yasunobu Yoshikai, Hisakata Yamada 2008

[雑誌論文] Identification of CD25+ gammadelta T cells as fetal thymus-derived naturally occurring IL-17 producers.

Shibata K, Yamada H, Nakamura R, Sun X, Itsumi M, Yoshikai Y. 2008

[雑誌論文] Thl but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

Yamada H, Nakashima Y, Okazaki K, Mawatari T, Fukushi JI, Kaibara N, Hori A, Iwamoto Y, Yoshikai Y. 2008