トップ研究者を探す延長仮骨の骨癒合促進法の開発

延長仮骨の骨癒合促進法の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-20390401
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
外科系臨床医学
整形外科学
研究機関 徳島大学
代表研究者 安井 夏生
研究分担者 高田 信二郎
研究分担者 松浦 哲也
研究分担者 二川 健
研究分担者 高橋 光彦
研究分担者 西良 浩一
研究期間 開始年月日 2008/4/1
研究期間 終了年度 2010
研究ステータス 完了 (2010/4/1)
配分額(合計) 19,760,000 (直接経費 :15,200,000、間接経費 :4,560,000)
配分額(履歴) 2010年度:2,470,000 (直接経費 :1,900,000、間接経費 :570,000)
2009年度:5,330,000 (直接経費 :4,100,000、間接経費 :1,230,000)
2008年度:11,960,000 (直接経費 :9,200,000、間接経費 :2,760,000)
キーワード 仮骨延長
骨成長因子
持続投与
distraction
osteogenesis
osteoenesis

研究成果

[学会発表] Enhanced bone healing by local infusion of FGF-2 and bisphosphonate during distraction osteogenesis.

Yasui N, Takahashi M, Yukata K, Abbaspour A, Takata S, Sairyo K 2010

[雑誌論文] Specificity of fusion genes in adipocytic tumors.

Kubo T, Matsui Y, Naka N, Araki N, Myoui A, Endo K, Yasui N, Ohtani O, Suzuki K, Kimura T, Yoshikawa H, Ueda T 2010

[雑誌論文] Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells.

Yukata K, Matsui Y, Shukunami C, Takimoto A, Hirohashi N, Ohtani O, Kimura T, Hiraki Y, Yasui N 2010

[学会発表] Diverse Muscle Architectural Adaptations to Single Level Limb Lengthening.

Takahashi M, Mizobuchi T, Homma Y, Yasui N 2010

[学会発表] Circumferential periosteal stripping of femoral diaphysis of developing rat produces longitudinal overgrowth and cortical hypertrophy.

Takata S, Enishi T, Takahashi M, Nishisho T, Yasui N 2010

[学会発表] A special drill guide for percutaneous multidriling osteotomy for limb lengthening.

安井夏生, 高橋光彦, 川崎賀照 2010

[学会発表] Strategy and outcome of limb reconstruction for fibular hemimelia type II.

Takahashi M, Kawasaki Y, Yasui N 2010

[雑誌論文] Myxoid liposarcoma with EWS-CHOP type 1 fusion gene.

Suzuki K, Matsui Y, Endo K, Kubo T, Hasegawa T, Kimura T, Ohtani O, Yasui N 2010

[学会発表] Enhanced bone healing by local infusion of FGF-2 and bisphosphonate during distraction osteogenesis

Yasui N, et al. 2010

[学会発表] The a 3 isoform of V-ATPase is critical to bone and lung metastasis.

Nishisho T, Hata K, Nakanishi M, Wang L, Morita Y, 安井夏生, Yoneda T 2010

[雑誌論文] Fragmental bone transport in conjunction with acute shortening followed by gradual lengthening for a failed infected nonunion of the tibia.

Takahashi M, Kawasaki Y, Matsui Y, Yasui N 2010

[学会発表] Orthofix-MBA Symposium 「Biological techniques for accelerating consolidation of regenerate」.

安井夏生 2010

[雑誌論文] Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese.

Nishimoto K, Kochi Y, Ikari K, Yamamoto K, Suzuki A, Shimane K, Nakamura Y, Yano K, Iikuni N, Tsukahara S, Kamatani N, Okamoto H, Kaneko H, Kawaguchi Y, Hara M, Toyama Y, Horiuchi T, Tao K, Yasutomo K, Hamada D, Yasui N, Inoue H, Itakura M, Yamanaka H, Momohara S 2010

[学会発表] Orthofix-MBA Symposium 「Biological techniques for accelerating consolidation of regenerate」

Yasui N 2010

[学会発表] A special drill guide for percutaneous multidriling osteotomy for limb lengthening

Yasui N, et al. 2010

[学会発表] ビスホスホネートによる仮骨形成促進

高橋光彦、Aziz Abbaspour、高田信二郎、西良浩一、松井好人、川崎賀照、油形公則、乾亜美、安井夏生 2009

[雑誌論文] Optimal increase in bone mass by continuous local infusion of alendronate during distraction osteogenesis in rabbits.

Abbaspour A, Takahashi M, Sairyo K, Takata S, Yukata K, Inui A, Yasui N 2009

[雑誌論文] Ubiquitin Ligase Cbl-b Is a Negative Regulator for Insulin-Like Growth Factor 1 Signaling during Muscle Atrophy Caused by Unloading.

Nakao R, Hirasaka K, Goto J, Ishidoh K, Yamada C, Ohno A, Okumura Y, Nonaka I, Yasutomo K, Baldwin KM, Kominami E, Higashibata A, Nagano K, Tanaka K, Yasui N, Mills EM, Takeda S, Nikawa T 2009

[学会発表] 骨格筋の特性が筋の伸張刺激に対する適応に与える影響

高橋光彦、溝渕貴俊、本間友佳子、江西哲也、菅沼勝義、安井夏生 2009

[雑誌論文] Bone fracture and the healing mechanisms. The mechanical stress for fracture healing in view of distraction osteogenesis.

Yukata K, Takahashi M, Yasui N 2009

[雑誌論文] Continuous local infusion of fibroblast growth factor-2 enhances consolidation of the bone segment lengthened by distraction osteogenesis in rabbit experiment.

Abbaspour A, Takata S, Sairyo K, Katoh S, Yukata K, Yasui N 2008

[雑誌論文] Altered fracture callus formation in chondromodulin-I deficient mice.

Yukata K, Matsui Y, Shukunami C, Takimoto A, Goto T, Nishizaki Y, Nakamichi Y, Kubo T, Sano T, Kato S, Hiraki Y, Yasui N 2008