研究成果

[図書] Year Note 2021　内科・外科編（分担執筆）

宇高恵子 2021

[学会発表] Efficient induction of effector T cells by peptide immunization in a micelle formula

.SHIMIZU Takeyuki, KASAI Michiyuki,　SAKAGUCHI　Naoki,　YAMASHITA　Yoshiko,　ONOUE　Kousuke,　TANAKA　Yuki,　IWASE　Youichiro,　UDAKA Keiko 2021

[学会発表] Construction of a platform to predict HLA-DRB1*04:05-binding peptides trained by query learning

Keiko Udaka, Morito Chabata 2021

[学会発表] Induction of T cell responses by peptide immunization delivered by a novel pyro-drive jet injector,Actranza

Toshihiro Komatsu, Michiyuki Kasai, Yuko Sakaguchi, Naoki Sakaguchi, Keiko Udaka 2021

[学会発表] SARS-CoV-2 spike L452R and Y453F variants confer escape from immunodominant HLA-A24-restricted T cell recognition

Chihiro Motozono, Hiroshi Hamana, Keiko Udaka, Hiroyuki Kishi, Takamasa Ueno 2021

[学会発表] The infiltration of tumor-specific regulatory T cells requires MHC class Ⅱ-expression on endothelial cells

UDAKA Keiko, KOMATSU Toshihiro, SHIMIZU Takeyuki, KUBOTA Yoshiaki 2021

[学会発表] 血管内皮細胞の抗原提示機能を活かした癌のペプチド免疫療法

宇高恵子 2020

[学会発表] Optimization of culture conditions and method of detection to monitor T cells specific for HLA-peptides in PBMCs

宇高恵子、中田あさみ、町田香織、小松利広、清水健之 2020

[雑誌論文] Carboxylated polyamidoamine dendron-bearing lipid-based assemblies for precise control of intracellular fate of cargo and induction of antigen-specific immune responses.

Eiji Yuba , Yoshikatsu Sugahara, Yuta Yoshizaki, Takeyuki Shimizu, Michiyuki Kasai, Keiko Udaka, Kenji Kono 2020

[学会発表] ペプチターゼ耐性ペプチドを用いたMHC class II結合性ペプチドの特異性解析と自動予測

宇高恵子 2019

[学会発表] Antigen specific infiltration of T cells guided by tumor endothelial cells　(国際シンポジウム)

Udaka K, Komatsu T, Noguchi Y 2019

[学会発表] Construction of a platform to predict HLA-A*11:01-binding peptides

小松利広、清水健之、町田香織、山下慶子、中村祥紀、宇高恵子 2019

[学会発表] 初発悪性神経膠腫に対するＷＴ1-W10免疫療法

川西　裕、宇高恵子、土肥　俊、八幡俊男、中居永一、福田　仁、福井直樹、上羽哲也 2019

[学会発表] ゲノム編集によるTAP欠損細胞を使ったMHCクラスI分子と抗原ペプチドの結合相互作用解析法

清水健之、小松利広、深澤太郎、片岡佐誉、宇高恵子 2019

[学会発表] Construction of a computational platform to predict HLA-A*11:01 binding peptides

Udaka　K, Komatsu T, Shimizu T 2019

[学会発表] HLA-ペプチド結合予測腫瘍のネオアンチゲンでの評価

尾上広祐、山下慶子、Brandon Malone、田中雄希、町田香織、宇高恵子 2019

[学会発表] A phase I clinical study of WT1 immunotherapy against bone and soft-tissue malignancies

Hirofumi Namba, Motohiro Kawasaki, Tatsuo Iiyama Masahiko Ikeuchi, Mistuhiko Miyamura, Shun Doi, Keiko Udaka 2019

[学会発表] Promiscuous binding of HLA-DRB1*04:05-binding peptides to other HLA class II molecules

有馬直輝、宇高恵子、池　成基、梅村孟司、笠島理加、小松利広、山下慶子、宮川知也、土肥俊、横山彰仁、北岡裕章 2019

[学会発表] CTL lines specific for a wild type tumor antigen exert tumor regulatory activity in vivo. A combination immunotherapy with an androgen antagonist and peptide induces effective anti-tumor responses

Kasai M, Komatsu T, Sakaguti N, Kishi H, Udaka K 2019

[学会発表] Augmentation of CTL-mediated anti-tumor responses by cross-presentation of a tumor antigen OVA by endothelial cells

笠井道之、青井二郎、山本快亮、木嶋美香、小松利広、岩出良介、森田志保、山上卓士、坂口奈央樹、辛島　尚、井上啓史、宇高恵子 2019

[学会発表] CTL lines specific for a wild type tumor antigen exert tumor regulatory activity in vivo

Kasai M, Komatsu T, Sakaguti N, Kishi H, Udaka K 2019

[学会発表] A phase I clinical study of WT1 immunotherapy against myelodysplastic syndrome

Taniguchi　A, Takeuchi　A, IkezoeT T, Kojima K, Yokoyama A, Miyamura M, Doi S, Udaka K 2019

[学会発表] ネオアンチゲン特異的ＣＴＬによる抗腫瘍効果の比較

長岡孝治、細井亮宏、孫　長博、小松利広、宇高恵子、垣見和宏 2019

[学会発表] Cross-presentation by ECs augments anti-tumor responses in targeting a natural tumor antigen in prostate cancer

山本快亮、笠井道之、小松利広、花立裕充、坂口奈央樹、浜名　洋、岸　裕幸、土肥俊、宇高恵子 2019

[学会発表] ホルモン療法抵抗性前立がんに発現される腫瘍抗原SNに対するCD8+T細胞株の樹立

花立裕充、笠井道之、小松利広、岸裕幸、土肥俊、宇高恵子 2019

[学会発表] WT抗原を標的とした前立腺癌に対するペプチドワクチン療法の臨床試験（第20報）

北島清彰、北島彰子、竹内　保、降幡睦夫、宇高恵子 2019