トップ研究者を探すアレルギー性結膜疾患発症における結膜抗原提示細胞の解析

アレルギー性結膜疾患発症における結膜抗原提示細胞の解析

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-19592025
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
眼科学
研究機関 高知大学
代表研究者 福島 敦樹
研究期間 開始年月日 2007/4/1
研究期間 終了年度 2008
研究ステータス 完了 (2008/4/1)
配分額(合計) 3,120,000 (直接経費 :2,400,000、間接経費 :720,000)
配分額(履歴) 2008年度:1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
2007年度:1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
キーワード アレルギー性結膜炎
マウス
好酸球
T細胞
抗原提示細胞
マクロファージ共刺激分子
CD11b
F4
80
マクロファージ
抗原提示細
樹状細胞
共刺激分子

研究成果

[雑誌論文] Regulatory T cells participate in 4-1BB-mediated suppression of experimental allergic conjunctivitis

Sumi T, Ishida W, Mittler RS, Yagita H, Taguchi O, Fukushima A. 2009

[雑誌論文] Activation of tumor necrosis factor-related apoptosis-inducing ligand receptor enhances the severity of murine allergic conjunctivitis

Sumi T, Ishida W, Okumura K, Yagita H, Fukushima A. 2009

[雑誌論文] Treatment with FTY720 during the induction or effector phase suppresses the development of experimental allergic conjunctivitis in mice.

Sumi T, Fukushima A, Nishino K, Fukuda K, Kumagai N, Nishida T, Ueno H. 2009

[雑誌論文] Roles of galectin-9 in the development of experimental allergic conjunctivitis in mice

Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Okumura K, Akiba H, Yagita H, Ueno H. 2008

[雑誌論文] Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.

Fukushima A, Sumi T, Ishida W, Yamada J, Iwakura Y, Ueno H. 2008

[雑誌論文] Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.

Fukushima A, et al 2008

[雑誌論文] The Effect of a Combined Therapy with a Histamine H(1) Antagonist and a Chemical Mediator Release Inhibitor on Allergic Conjunctivitis.

Fujishima H, Fukagawa K, Tanaka M, Uchio E, Takamura E, Nakagawa Y, Miyazaki D, Fukushima A, Okamoto S, Yokoi N. 2008

[雑誌論文] Depletion of thymus-derived CD4+CD25+ T cells abrogates the suppressive effects of α-galactosylceramide treatment on experimental allergic conjunctivitis

Fukushima A, Sumi T, Ishida W, Ojima A, Kajisako M, Ueno H, Taguchi O. 2008

[雑誌論文] Roles of galectin-9 in the development of experimental allergic conjunctivitis in mice.

Fukushima A, et al 2008

[図書] 新眼科薬物療法のコツと落とし穴 : 春季カタルにおける免疫抑制剤点眼の使い方

福島敦樹 2008

[雑誌論文] Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis

Fukushima A, Sumi T, Ishida W, Ojima A, Kajisako M, Koyanagi A, Koyama N, Yagita H. 2008

[雑誌論文] CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice

Sumi T, Ishida W, Ojima A, Kajisako M, Sakanishi T, Yagita H, Fukushima A. 2008

[雑誌論文] Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis.

Fukushima A, et al 2008

[雑誌論文] Cryptomeria japonica-induced allergic conjunctivitis in mice

Fukushima A, Shii D, Sumi T, Kageyama T,Ueno H. 2007

[雑誌論文] Antibodies to T-cell Ig and mucin domain-containing proteins(Tim)-1 and-3 suppress the induction and progression of murie allergic conjunctivitis

Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Akiba H, Okumura K, Yagita H, Ueno H. 2007

[雑誌論文] T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase

Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Okumura K, Akiba H, Yagita H, Ueno H. 2007

[雑誌論文] B7-H3 regulates the development of experimental allergic conjunctivitis in mice

Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Yamazaki T, Akiba H, Okumura K, Yagita H, Ueno H. 2007

[雑誌論文] Therapeutic effects and mechanisms of action of cyclosporine A ophthalmic solution in the treatment of vernal keratoconjunctivitis.

Shii D, Fukushima A. 2007

[雑誌論文] Roles of CD4+CD25+T cells in the development of experimental murine allergic conjunctivitis

Fukushima A, Yamaguchi T, Sumi T, Fukuda K, Kumagai N, Nishida T, Takeuchi M, Taguchi O, Ueno H. 2007

[雑誌論文] Thymus-derived CD4+CD25+T cells suppress the development of murine allergic conjunctivitis

Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, Takeuchi M, Taguchi O, Ueno H. 2007

[雑誌論文] Roles of T cells in the development of allergic conjunctival diseases

Fukushima A. 2007

[雑誌論文] B7-H3 regulates the development of experimental allergic conjunctiviti s in mice

Fukushima A, Sumi T, Fukuda K, Kumagai N, Nishida T, Yamazaki T, Akiba H, Okumura K, Yagita H, Ueno H. 2007

[雑誌論文] Endogenous IL-10 produced by antigen-irrelevant cells promotes the development of experimental murine allergic conjunctivitis

Fukushima A, Sumi T, Fukuda K, kumagai N, Nishida T, Ueno H 2007

[雑誌論文] Cryptomeria japonica-induced allergic conjunctivitis in mice

Fukushima A, Shii D, Sumi T, Kageyama T, Ueno H 2007

[雑誌論文] Differential contributions of B7-1 and B7-2 to the development or murine experimental allergic conjunctivitis

Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, Yagita H, Ueno H. 2007