トップ研究者を探す頸動脈プラーク不安定機構に関わるプロテオグリカンの意義とその制御

頸動脈プラーク不安定機構に関わるプロテオグリカンの意義とその制御

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-19591681
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
脳神経外科学
研究機関 徳島大学
代表研究者 宇野 昌明
研究分担者 永廣 信治
研究分担者 松原 俊二
研究分担者 西 京子
研究期間 開始年月日 2007/4/1
研究期間 終了年度 2008
研究ステータス 完了 (2008/4/1)
配分額(合計) 4,420,000 (直接経費 :3,400,000、間接経費 :1,020,000)
配分額(履歴) 2008年度:2,210,000 (直接経費 :1,700,000、間接経費 :510,000)
2007年度:2,210,000 (直接経費 :1,700,000、間接経費 :510,000)
キーワード 頸動脈病変
CEA
decorin
biglycan
HCII
HC II

研究成果

[雑誌論文] Endothelial damage due to impaired NO bioavailability triggers cerebral aneurysm formation in female rats-Endothelial damage and cerebral aneurysm

Tamura T, Jamous MA, Kitazato KT, Yagi K, Tada Y, Uno M, Nagahiro S. 2009

[雑誌論文] Primary anaplastic pleomorphic xanthoastrocytoma with widespread neuroaxis dissemination atdiagnosis--a pediatric case report and review of the literature

Okazaki T, Kageji T, Matsuzaki K, Horiguchi H, Hirose T, Watanabe H, Ohnishi T, Nagahiro S. 2009

[雑誌論文] embolization during carotid angioplasty and carotid artery stenting

Yamasaki H, Matsubara S, Sasaki I, Nagahiro S. 2009

[雑誌論文] Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator

Yagi K, Kitazato KT, Uno M, Tada Y, Kinouchi T, Shimada K, Nagahiro S 2009

[学会発表] EDARAVONE, A FREE RADICAL SCAVENGER, INHIBITS MMP-9-RELATED BRAIN HEMORRHAGE IN RATS TREATED WITH TISSUE PLASMINOGEN ACTIVATOR

Uno M, Yagi K, Kitazato KT, Tada Y, Kinouchi T, Tamura T, Nagahiro S. 2008

[学会発表] SYSTEMIC- AND FOCAL EFFECTS OF CANDESARTAN AGAINST CEREBRAL ISCHEMIA

Kitazato KT, Uno M, Yagi K, Mull, Tamura T, Tada Y, Kinouchi T, Shimada K, Nagahiro S. 2008

[雑誌論文] Choreoathetosis due to rupture of a distal accessory anterior cerebral artery aneurysm

Morigaki R, Uno M, Matsubara S, Satoh K, Nagahiro S. 2008

[雑誌論文] Bilateral deep brain stimulation of the glohus pallidus internus in tardive dystonia

Sako W, Goto S, Shimazu H, Murase N, Matsuzaki K, Tamura T, Mure H, Tomogane Y, Arita N, Yoshikawa H, Nagahiro S, Kaji R. 2008

[学会発表] a free radical scavenger, inhibits MMP-9 related brain hemorrhage in rats treated with tissue plasminogen activator

Uno M, Yagi K, Kitazato KT, Tada Y, Nagahiro S. 2008

[雑誌論文] Protective mechanisms of the angiotensin II type 1 receptor blacker candesartan against cerebral ischemia

Liu H, Kitazato KT, Uno M, Yagi K, Kanematsu Y, Tamura T, Tada Y, Kinouchi T, Nagahiro S 2008

[雑誌論文] 3-tesla MRI in acute stroke patients

Morita N, Harada M, Uno M, Matsubara S, Matsuda T, Nagahiro S, Nishitani H. 2008

[雑誌論文] Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia

Sato K, Sumi-Ichinose C, Kaji R, Ikemoto K, Nomura T, Nagatsu I, Ichinose H, Ito M, Sako W, Nagahiro S, Graybiel AM, Goto S. 2008

[雑誌論文] Comparison between early and late carotid endarterectomy for symptomatic carotid stenosis in relation to oxidized low-density lipoprotein and plaque vulnerability

Suzue A, Uno M, Kitazato KT, Nishi K, Yagi K, Liu H, Tamura T, Nagahiro S. 2007

[雑誌論文] Comparison between early and late carotid endarterectomy for symptomatic carotid stenosis in relation to oxidized LDL and plaque vulnerability.

Suzue A, Uno M, Kitazato TK, Nishi K, Liu H, Yagi K, Tamura T, Nagahiro S. 2007

[雑誌論文] Hemodynamic cerebral ischemia during carotid endarterectomy evaluated by intraoperative monitoring and post-operative diffusion-weighted imaging

Uno M, Suzue A, Nishi K, Nagahiro S. 2007

[雑誌論文] Hemodynamic cerebral ischemia during carotid endarterectomy evaluated by intraoperative monitoring and postoperative diffusion-weigted imaging.

Uno M, Suzue A, Nishi K, Nagahiro S 2007

[雑誌論文] Endothelial injury and inflammatory response induced by hemodynamic changes preceding intracranial aneurysm formation : experimental study in rats

Jamous MA, Nagahiro S, Kitazato KT, Tamura T, Aziz HA, Shona M, Satoh K 2007

[雑誌論文] Vascular reconstruction (chronic)- CEA, STA-MCA anastomosis

Nishi K, Uno M, Nagahiro S. 2006

[雑誌論文] Hemichorea due to hemodynamic ischemia associated with extracranial carotid artery stenosis

Morigaki R, Uno M, Suzue A, Nagahiro S. 2006

[雑誌論文] Surgical indication and selection of surgical procedure for hypertensive subcortical hemorrhage

Toi H, Uno M, Nagahiro S. 2006