消化器がんの腫瘍発生に於ける糖鎖修飾の関与

トップ›研究者を探す›消化器がんの腫瘍発生に於ける糖鎖修飾の関与

代表研究者	西田俊朗
研究課題番号	KAKENHI-PROJECT-19390349
研究種目	基盤研究(B)
研究分野	生物系医歯薬学外科系臨床医学消化器外科学
研究機関	大阪大学
研究分担者	三善英知
研究分担者	廣田誠一
研究分担者	仲哲治
連携研究者	廣田誠一
連携研究者	仲哲治
研究期間開始年月日	2007/4/1
研究期間終了年度	2009
研究ステータス	完了 (2009/4/1)
配分額（合計）	18,070,000 (直接経費 :13,900,000、間接経費 :4,170,000)
配分額（履歴）	2009年度：4,290,000 (直接経費 :3,300,000、間接経費 :990,000) 2008年度：4,160,000 (直接経費 :3,200,000、間接経費 :960,000) 2007年度：9,620,000 (直接経費 :7,400,000、間接経費 :2,220,000)
キーワード	糖鎖修飾消化管間質腫瘍 KITチロシンキナーゼ遺伝子変異マイクロアレイプロテオーム解析 GIST

研究成果

[雑誌論文] ガイドラインに則したGISTの診断と治療指針

山下雅史、赤松大樹、仲原正明、西田俊朗 2010

[雑誌論文] Salvage esophagectomy after definitive chemoradiotherapy for thoracic esophageal cancer.

Miyata H, Yamasaki M, Takiguchi S, Nakajima K, Fujiwara Y, Nishida T, Mori M, Doki Y. 2009

[雑誌論文] Partial gastrectomy using natural orifice translumenal endoscopic surgery (NOTES) for gastric submucosal tumors: early experience in humans.

Nakajima K, Nishida T, Takahashi T, Souma Y, Hara J, Yamada T, Yoshio T, Tsutsui T, Yokoi T, Mori M, Doki Y. 2009

[雑誌論文] The role of intraoperative carbon dioxide insufflating upper gastrointestinal endoscopy during laparoscopic surgery.

Souma Y, Nakajima K, Takahashi T, Nishimura J, Fujiwara Y, Takiguchi S, Miyata G, Yamasaki M, Doki Y, Nishida T. 2009

[雑誌論文] Cytokeratins 18 and 8 are poor prognostic markers in patients with squamous cell carcinoma of the oesophagus.

Makino T, Yamasaki M, Takeno A, Shirakawa M, Miyata H, Takiguchi S, Nakajima K, Fujiwara Y, Nishida T, Matsuura N, Mori M, Doki Y. 2009

[雑誌論文] a Chinese herbal medicine, improves stasis of patients with pylorus-preserving gastrectomy

akahashi T, Endo S, Nakajima K, Souma Y, Nishida T. Rikkunshito 2009

[雑誌論文] Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene.

Nishida T, Takahashi T, Nishitani A, Doi T, Shirao K, Komatsu Y, Nakajima K, Hirota S 2009

[学会発表] Detection of cis-mutations in the activation loop of the KIT gene in sunitinib-resistant gastrointestinal stromal tumors.

T. Nishida. T. Takahashi, K. Nakajima, A. Nishitani, S. Hirota 2008

[学会発表] Laparoscopic approaches for submucosal tumors in the esophagogastric junction

NishidaT. T Takahashi, Y Souma, J Nishimura, S Takiguchi, Y Fujiwara, Yo Doki, K Nakajima 2008

[雑誌論文] Aberrant Expression of Glycosylation in Juvenile Gastrointestinal Stromal Tumors.

Takahashi T, Naka T, Fujimoto M, Serada S, et al 2008

[雑誌論文] 胃粘膜下腫瘍

大森健、中島清一、仲原正明、西田俊朗 2008

[雑誌論文] Transvaginal endoscopic partial gastrectomy in porcine models: Role of "another" endoscope for gastric control.

Nakajima K, Takahashi T, Souma Y, Shinzaki S, Yamada T, Yoshio T, Nishida T. 2008

[雑誌論文] A mouse model of human multiple GIST family with KIT-Asp820Tyr mutation generated by knock-in strategy.

Nakai N, Ishikawa T, Nishitani A, Liu NN, Shincho M, Hao H, Isozaki K, Kanda T, Nishida T, Fujimoto J Hirota S. 2008

[学会発表] Detection of cis-mutations in the activation loop of the KIT genein sunitinib-resistant gastrointestinal stromal tumors.

Nishida T, Takahashi T, Nakajima K, et al. 2008

[雑誌論文] Is it really necessary to close gastrotomy in NOTES? A lesson learned from laparoscopic intragastric surgery

Nakajima K, Souma Y, Ohashi S, Nishida T. 2008

[学会発表] Aberrant Glycosylation in Juvenile Gastrointestinal Stromal Tumors.

T Nishida, T Takahashi, Yo Souma, S Hirota, T Naka 2008

[学会発表] etection of cis-mutations in the activation loop of the KIT gene in sunitinib-resistant gastrointestinal stromal tumors.

NishidaT. T Takahashi, K Nakajima, A Nishitani, S Hirota 2008

[雑誌論文] Laparoscopic intragastric surgery under carbon dioxide pneumostomach.

Omori T, Nakajima K, Taniguchi E, Ohashi S, Nishida T. 2008

[雑誌論文] Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib-resistant gastrointestinal stromal tumor.

Nishida T, Kanda T, Nishitani A, Takahashi T, Nakajima K, Ishikawa T, Hirota S. 2008

[雑誌論文] Aberrant Expression of Glycosylation in Juvenile Gastrointestinal Stromal Tumors.

Takahashi T, Naka T, Fujimoto M, Serada S, Horino J, Terabe F, Hirota S, Miyoshi E, Hirai T, Nakajima K, Nishitani A, Souma Y, Sawa Y, Nishida T. 2008

[学会発表] Impact and resistance to Imatinib on Advanced gastric Gastrointestinal Stromal Tumor.

NishidaT. Takahashi T. Nakajima K. Doki Y. Monden M. Hirota S 2007

[雑誌論文] Proteomics-based identification of alpha-enolase as a tumor antigen in non-small lung cancer.

He P, Naka T, Serada S, Fujimoto M, Tanaka T, Hashimoto S, Shima Y, Yamadori T, Suzuki H, Hirashima T, Matsui K, Shiono H, Okumura M, Nishida T, Tachibana I, Norioka N, Norioka S, Kawase I 2007

[雑誌論文] An enhanced risk group stratification system for more practical prognostication

Takahashi T, Nakajima K, Nishida T, et. al. 2007

[雑誌論文] urgical strategy for gastric gastrointestinal stromal tumors: laparoscopic vs.

Nishimura J, Nakajima K, Omori T, Takahashi T, Nishitani A, Ito T, Nishida T. 2007

[学会発表] Optimization of intragastric and transgastric insufflation for NOTES: a pilot assessment.

Nakajima K. Takahashi T. Souma Y. Nishida T 2007

[雑誌論文] Surgical strategy for gastric gastrointestinal stromal tumors: laparoscopic vs. open resection.

Nishimura J. Nakajima K, Nishida T, et. al. 2007

[雑誌論文] An enhanced risk-group stratification system for more practical prognostication of clinically malignant gastrointestinal stromal tumors.

Takahashi T, Nakajima K, Nishitani A, Souma Y, Hirota S, Sawa Y, Nishida T. 2007