トップ›研究者を探す›間質性肺炎・薬剤性肺障害の臨床像とゲノム解析の日欧比較研究

間質性肺炎・薬剤性肺障害の臨床像とゲノム解析の日欧比較研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-19390224
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
内科系臨床医学
呼吸器内科学
研究機関 広島大学
代表研究者 河野 修興
研究分担者 横山 彰仁
研究分担者 服部 登
研究分担者 石川 暢久
研究期間 開始年月日 2007/4/1
研究期間 終了年度 2009
研究ステータス 完了 (2009/4/1)
配分額（合計） 18,850,000 (直接経費 :14,500,000、間接経費 :4,350,000)
配分額（履歴） 2009年度：3,510,000 (直接経費 :2,700,000、間接経費 :810,000)
2008年度：3,380,000 (直接経費 :2,600,000、間接経費 :780,000)
2007年度：11,960,000 (直接経費 :9,200,000、間接経費 :2,760,000)
キーワード 呼吸器病学
間質性肺炎
バイオマーカー
薬剤性肺障害
人種差
医療・福祉
ゲノム
糖鎖
マイクロアレイ

研究成果

[雑誌論文] Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis.

Senoo T, Hattori N, Tanimoto T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Murai H, Yokoyama A, Kohno N 2010

[雑誌論文] Lymphocyte transformation test is not helpful for the diagnosis of methotrexate-induced pneumonitis in patients with rheumatoid arthritis.

Hirata S, Hattori N, Kumagai K, Haruta Y, Yokoyama A, Kohno N 2009

[雑誌論文] Airflow limitation in smokers is associated with subclinical atherosclerosis.

Iwamoto H, Yokoyama A, Kitahara Y, Ishikawa N, Haruta Y, Yamane K, Hattori N, Hara H, Kohno N 2009

[雑誌論文] Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.

animoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Igarashi K, Kohno N 2009

[図書] んがで読み解く呼吸器症例100

河野修興監修,横山彰仁,森山美智子,服部登(編集) 2009

[雑誌論文] Airflow Limitation in Smokers is Associated with Subclinical Atherosclerosis

Iwamoto H, Yokoyama A, Kitahara Y, et al 2009

[雑誌論文] Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.

Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N 2009

[雑誌論文] IL-12p40 is essential for the down-regulation of airway hyperresponsiveness in a mouse model of bronchial asthma with prolonged antigen exposure.

Onari Y, Yokoyama A, Haruta Y, Nakashima T, Iwamoto H, Hattori N, Kohno N 2009

[雑誌論文] Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.

Ishikawa N, Hattori N, Yokoyama A, Tanaka S, Nishino R, Yoshioka K, Ohshimo S, Fujitaka K, Ohnishi H, Hamada H, Arihiro K, Kohno N 2008

[雑誌論文] Suppressor of cytokine signaling 1 inhibits pulmonary inflammation and fibrosis

Nakashima T, Yokoyama A, Onari Y, Shoda H, Haruta Y, Hattori N, Naka T, Kohno N 2008

[雑誌論文] Circulating KL-6/MUC1 as an independent predictor for disseminated intravascular coagulation in acute respiratory distress syndrome.

Nakashima T, Yokoyama A, Ohnishi H, Hamada H, Ishikawa N, Haruta Y, Hattori N, Tanigawa K, Kohno N 2008

[雑誌論文] Anti-inflammatory effects and clinical efficacy of theophylline and tulobuterol in mild-to-moderate chronic obstructive pulmonary disease.

Kanehara M, Yokoyama A, Tomoda Y, Shiota N, Iwamoto H, Ishikawa N, Taooka Y, Haruta Y, Hattori N, Kohno N 2008

[雑誌論文] Differential expression of the glycosylated forms of MUC1 during lung development.

Sakurai J, Hattori N, Nakajima M, Moriya T, Suzuki T, Yokoyama A, Kohno N 2007

[図書] 呼吸器疾患最新の治療2007-2009

横山 彰仁 2007

[図書] 呼吸器専門医テキスト

横山 彰仁 2007

[雑誌論文] Productive cough is an independent risk factor for the development of COPD in former smokers.

Yamane T, Hattori N, Kitahara Y, Haruta Y, Sasaki H, Yokoyama A, Kohno N