トップ研究者を探す肝癌に対する複合的免疫遺伝子治療:樹状細胞機能増強による免疫監視システム再構築

肝癌に対する複合的免疫遺伝子治療:樹状細胞機能増強による免疫監視システム再構築

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-19390200
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
内科系臨床医学
消化器内科学
研究機関 香川大学
代表研究者 出口 章広
研究分担者 正木 勉
連携研究者 正木 勉
研究期間 開始年月日 2007/4/1
研究期間 終了年度 2009
研究ステータス 完了 (2009/4/1)
配分額(合計) 18,330,000 (直接経費 :14,100,000、間接経費 :4,230,000)
配分額(履歴) 2009年度:4,160,000 (直接経費 :3,200,000、間接経費 :960,000)
2008年度:6,240,000 (直接経費 :4,800,000、間接経費 :1,440,000)
2007年度:7,930,000 (直接経費 :6,100,000、間接経費 :1,830,000)
キーワード 肝癌
肝硬変
サイトカイン
樹状細胞

研究成果

[雑誌論文] The close relationship between life-threatening breathing disorders and urine storage dysfunction in multiple system atrophy.

Deguchi K, Masaki T, 7others (last) 2010

[雑誌論文] Operative management of solitary intra-abdominal recurrence of hepatocellular carcinoma

Sano T, Izuishi K, Takebayashi R, Masaki T, Suzuki Y 2010

[雑誌論文] High concentration of lactic dehydrogenase in small volumes of ascites

Izuishi K, Masaki T, Suzuki Y 2010

[雑誌論文] Clinical characteristics of patients with hepatitis C virus-related chronic liver disease seropositive for anticentromere antibody

Himoto T, Masaki T, Deguchi A, 9others (5, 7)thnd 2009

[雑誌論文] Immunohistochemically detected expression of p27(Kip1) and Skp2 predicts survival in patients with intrahepatic cholangiocarcinomas

Hashimoto N, Masaki T, 20others (7)nd 2009

[雑誌論文] Education and imaging. Hepatobiliary and pancreatic:Isolated diaphragmatic metastasis from hepatocellular carcinoma

Sano T, Izuishi K, Takebayashi R, Kushida Y, Masaki T, Suzuki Y 2009

[雑誌論文] Cytomegalovirus-associated Acute Gastric Mucosal Lesion in an Immunocompetent Host

Himoto T, Masaki T, 13 others (11)nd 2009

[雑誌論文] Authors' reply

Kinekawa F, Masaki T, 10 others (2nd) 2009

[雑誌論文] Paraneoplastic necrotizing myelopathy in a patient with advanced esophageal cancer: An autopsied case report

Urai Y, Masaki T, 12 others (last) 2009

[雑誌論文] Hepatic von Meyenburg complex:a triggre of severe portal hypertension

Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T 2009

[雑誌論文] MicroRNA and hepatocellular carcinoma

Masaki T 2009

[雑誌論文] Tokumitsu H, Identification and Characterization of Wolframin

Yurimoto S, Masaki T, 6 others (6)nd 2009

[雑誌論文] Esophageal function worsens with long duration of diabetes

Kinekawa F, Masaki T, 10 others (last author) 2008

[雑誌論文] Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma

Mohammad SH, Yoneyama H, Deguchi A, Himoto T, Masaki T, 20 others (12th, last author) 2008

[雑誌論文] How many cytological examinations should be performed for the diagnosis of malignant biliary stricture via an endoscopic nasobiliary drainage tube?

Uchida N, Masaki T, 5 others (4th) 2008

[雑誌論文] Modulating effect of the PI3-kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells

Fujiwara M, Izuishi K, Sano T, Hossain MA, Kimura S, Masaki T, Suzuki Y 2008

[雑誌論文] A combination therapy of ethanol injection and radiofrequency ablation under general anesthesia for the treatment of hepatocellular carcinoma

Kurokohchi K, Yoneyama H, Deguchi A, Masaki T, Himoto T, 6 others (4, 5)ththh 2008

[雑誌論文] Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma

Mohammad SH, Deguchi A, Masaki T 2008

[雑誌論文] A method for measuring the three-dimensional refractive-index distribution of single cells using proximal two-beam optical tweezers and a phase-shifting mach-zehnder interferometer

Yasokawa T, Masaki T, 5 others (5th) 2007

[雑誌論文] Abundance of microRNA target motifs in the 3'-UTRs of 20527 humangenes.

Iwama H, Masaki T, Kuriyama S 2007

[雑誌論文] Usefulness of single and repetitive percutaneous transhepatic gallbladder aspiration for the treatment of acute cholecystitis.

Tsutsui K, Masaki T, 11 Others (11th) 2007

[雑誌論文] A double filtering method for measuring the translational velocity of fluorescently stained cells

Yasokawa T, Ishimaru I, Kuriyama S, Masaki T, Takegawa K, Tanaka N 2007

[雑誌論文] ndrd Successful treatment of hypovascular advanced hepatocellular carcinoma with lipiodol-targetting intervention radiology

Kurokohchi K, Deguchi A, Masaki T, Himoto T, Yoneyama H, 7 orhers (2, 3) 2007

[雑誌論文] ndrd Comparative study of the effects of percutaneous ethanol injection and radiofrequency ablation in cases treated with a straight or expandable electrode

Kurokohchi K, Deguchi A, Masaki T, Yoneyama H, Himoto T, 4 others 2007

[雑誌論文] Utility of pancreatic duct brushing for diagnosis of pancreatic carcinoma

Uchida N, Masaki T, 8 Others (6nd) 2007

[雑誌論文] thth Efficacy of zinc administration in patients with hepatitis C virus-related chronic liver disease

Himoto T, Deguchi A, Masaki T, 9 others (4, 8) 2007

[雑誌論文] rdthVitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells

Ogawa M, Deguchi A, Masaki T, 5 others (3, 5) 2007

[雑誌論文] thth Sequential assessment of the intrahepatic expression of epidermal growth factor and transforming growth factor-beta1 in hepatofibrogenesis of a rat cirrhosis model

Kuriyama S, Deguchi A, Masaki T, 12 others (8, 13) 2007

[雑誌論文] Abundance of microRNA target motifs in the 3'-UTRs of 20527human genes

Iwama H, Masaki T, Kuriyama S. 2007

[雑誌論文] Technique for measuring the rotational velocity of a single cell.

Yasokawa T, Masaki T, 6 others (6th) 2007

[雑誌論文]

Yamamoto K, Masaki T, 6 others (6th) 2007

[雑誌論文] Activation of c-Yes in hepatocellular carcinoma: A preliminary study

Feng H, Masaki T, Deguchi A, 14 others (2nd, 7th) 2006

[雑誌論文] Three-dimensional phase-contrast imaging of single floating cells

Kobayashi H, Masaki T, 7others (6th) 2006

[雑誌論文] Multidisciplinary treatment of patients with hepatocellular carcinoma

Masaki T, Morishita A, Kurokohchi K, Kuriyama S 2006

[雑誌論文] Further resolution of alpha-fetoprotein glycoforms by two-dimensional isoelectric focusing and lectin affinity electrophoresis

Ichikawa E, Masaki T, 5 others (5th) 2006

[雑誌論文] Imaging technology of three dimensional distribution for sugar chain on single living cell-membrane

Yamamoto K, Masaki T, 9 others (11th) 2006

[雑誌論文] Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: Involvement in the early stages of hepatocarcinogenesis

Nonomura T, Masaki T, Himoto T, 9 others (2nd) 2006

[雑誌論文] Successful treatment of large-size advanced hepatocellular carcinoma by transarterial chemoembolization followed by the combination therapy of percutaneous ethanol-lipiodol injection and radiofrequency ablation

Kurokohchi K, Masaki T, Yoneyama H, 9 others (9)th 2006

[雑誌論文] Attitudinal manipulation of an optically trapped bacillary probe by controlling the distance between focal points for local dosing in cells.

Yasokawa T, Masaki T, 7 others (5th) 2006

[雑誌論文] Variable phase-contrast fluorescence spectrometry for fluorescently stained cells

Inoue Y, Masaki T, 7 others (5th) 2006

[雑誌論文] Displacement measurement of the depth migration of transparent cells

Yoshida M, Masaki T, 7others (6th) 2006

[雑誌論文] Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer.

Jian G, Masaki T, 18 others (last)