トップ研究者を探す関節組織再生における関節リウマチ治療薬の薬理効果プロファイリング

関節組織再生における関節リウマチ治療薬の薬理効果プロファイリング

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18K08389
研究種目 基盤研究(C)
研究分野
研究機関 愛媛大学
代表研究者 劉 爽
研究期間 開始年月日 2018/4/1
研究期間 終了年度 2020
研究ステータス 完了 (2020/4/1)
配分額(合計) 4,420,000 (直接経費 :3,400,000、間接経費 :1,020,000)
配分額(履歴) 2020年度:1,170,000 (直接経費 :900,000、間接経費 :270,000)
2019年度:1,560,000 (直接経費 :1,200,000、間接経費 :360,000)
2018年度:1,690,000 (直接経費 :1,300,000、間接経費 :390,000)
キーワード 間葉系幹細胞
関節リウマチ
軟骨移植
免疫抑制薬
軟骨再生
異種移植モデル
関節再生能
軟骨細胞
関節軟骨再生
抗リウマチ薬
免疫抑制剤
ゲノム編集

研究成果

[雑誌論文] Tachykinin-1 receptor antagonism suppresses substance-P- and compound 48/80-induced mast cell activation from rat mast cells expressing functional mas-related GPCR B3

Sahid MNA, Liu S, Mogi M, Maeyama K 2020

[雑誌論文] Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress

Kiyoi T, Liu S, Takemasa E, Nakaoka H, Hato N, Mogi M 2020

[雑誌論文] A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis

Suzuki Y, Liu S, Ogasawara T, Sawasaki T, Takasaki Y, Yorozuya T, Mogi M 2020

[学会発表] Immune system observation in a murine sarcopenic model

Tomoya Kawanami, Masaki Mogi, Shuang Liu 2020

[学会発表] Establishment of a drug screening system for chondrogenic differentiation of mesenchymal stem cells

Marina Ishida, Shuang Liu, Masaki Mogi 2020

[雑誌論文] Denervation‐induced loss of skeletal muscle mass influences immune homeostasis and accelerates the disease progression of lupus nephritis

Liu S, Kiyoi T, Takemasa E, Mogi M 2020

[雑誌論文] Assessment and comparison of the efficacy of methotrexate, prednisolone, adalimumab, and tocilizumab on multipotency of mesenchymal stem cells

Liu S, Kiyoi T, Ishida M, Mogi M 2020

[学会発表] Establishment of a drug screening system for chondrogenic differentiation of mesenchymal stem cells.

Ishida M, Liu S, Mogi M 2019

[雑誌論文] Controlled isoflurane anesthesia exposure is required for reliable behavioral testing in murine surgical models

Toyama K, Spin JM, Abe Y, Suzuki Y, Deng AC, Wagenhauser MU, Yoshino T, Mulorz J, Liu S, Tsao PS, Mogi M 2019

[学会発表] The influence of sarcopenia on immune hemostasis

Kawanami T, Liu S, Mogi M 2019

[学会発表] Down-regulation of intracellualr vesicle trafficking by the treatment of zoledronate in mast cells

Liu S, Mogi M 2018

[学会発表] Regulation of mutiple differentiation potential in mesenchymal stem cells via an intercellular Ca2+ signaling pathway

Liu S 2018

[雑誌論文] High-throughput screening system for dynamic monitoring of exocytotic vesicle trafficking in mast cells

Kiyoi Takeshi、Liu Shuang、Sahid Muhammad Novrizal Abdi、Shudou Masachika、Maeyama Kazutaka、Mogi Masaki 2018

[図書] Rheumatoid Arthritis: Methods and Protocols

Liu S 2018

[学会発表] Modulation of multiple differetiation potential in mesenchymal stem cells via an intercellula calcium signaling pathway

Takahashi M, Liu S, Mogi M 2018