研究成果

[雑誌論文] Identification of prophylactic drugs for oxaliplatin-induced peripheral neuropathy using big data.

Zamami Y, Niimura T, Kawashiri T, Goda M, Naito Y, Fukushima K, Ushio S, Aizawa F, Hamano H, Okada N, Yagi K, Miyata K, Takechi K, Chuma M, Koyama T, Kobayashi D, Shimazoe T, Fujino H, Izawa-Ishizawa Y, Ishizawa K. 2022

[雑誌論文] Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity

Hamano H, Ikeda Y, Goda M, Fukushima K, Kishi S, Chuma M, Yamashita M, Niimura T, Takechi K, Imanishi M, Zamami Y, Horinouchi Y, Izawa-Ishizawa Y, Miyamoto L, Ishizawa K, Fujino H, Tamaki T, Aihara KI, 2021

[雑誌論文] Effects of Palonosetron on Nausea and Vomiting Induced by Multiple-Day Chemotherapy: A Retrospective Study

Hamano H, Mitsuhashi C, Suzuki Y, Zamami Y, Tsujinaka K, Okada N, Niimura T, Hayama T, Imai T, Ishida S, Sakamoto K, Goda M, Takechi K, Yagi K, Chuma M, Horinouchi Y, Shinomiya K, Ikeda Y, Kirino Y, Nakamura T, Yanagawa H, Hamada Y, Ishizawa K. 2021

[雑誌論文] Trends in hepatitis C virus‐associated mortality rates in Japan, 1998-2017

Hagiya Hideharu、Koyama Toshihiro、Deguchi Matsuo、Minato Yusuke、Miura Satomi、Funahashi Tomoko、Teratani Yusuke、Zamami Yoshito、Shinomiya Kazuaki、Kitamura Yoshihisa、Sendo Toshiaki、Hinotsu Shiro、Kano Mitsunobu 2021

[雑誌論文] Advanced Life Support vs. Basic Life Support for Patients With Trauma in Prehospital Settings: A Systematic Review and Meta-Analysis

Kondo Yutaka、Fukuda Tatsuma、Uchimido Ryo、Kashiura Masahiro、Kato Soichiro、Sekiguchi Hiroshi、Zamami Yoshito、Hifumi Toru、Hayashida Kei 2021

[雑誌論文] The Risk Factors Associated with Immune Checkpoint Inhibitor-Related Pneumonitis

Asada Mizuho、Mikami Takahisa、Niimura Takahiro、Zamami Yoshito、Uesawa Yoshihiro、Chuma Masayuki、Ishizawa Keisuke 2021

[雑誌論文] Population-Based Observational Study of Adverse Drug Event-Related Mortality in the Super-Aged Society of Japan

Funahashi Tomoko、Koyama Toshihiro、Hagiya Hideharu、Harada Ko、Iinuma Syunya、Ushio Soichiro、Zamami Yoshito、Niimura Takahiro、Shinomiya Kazuaki、Ishizawa Keisuke、Sendo Toshiaki、Hinotsu Shiro、Kano Mitsunobu R. 2021

[雑誌論文] Neuroimmunological adverse events associated with immune checkpoint inhibitor: a retrospective, pharmacovigilance study using FAERS database

Mikami Takahisa、Liaw Bobby、Asada Mizuho、Niimura Takahiro、Zamami Yoshito、Green-LaRoche Deborah、Pai Lori、Levy Michael、Jeyapalan Suriya 2021

[雑誌論文] Drug-Repositioning Approaches Based on Medical and Life Science Databases.

Zamami Y, Hamano H, Niimura T, Aizawa F, Yagi K, Goda M, Izawa-Ishizawa Y, Ishizawa K. 2021

[雑誌論文] Proton pump inhibitors block iron absorption through direct regulation of hepcidin via the aryl hydrocarbon receptor-mediated pathway

Hamano Hirofumi、Niimura Takahiro、Horinouchi Yuya、Zamami Yoshito、Takechi Kenshi、Goda Mitsuhiro、Imanishi Masaki、Chuma Masayuki、Izawa-Ishizawa Yuki、Miyamoto Licht、Fukushima Keijo、Fujino Hiromichi、Tsuchiya Koichiro、Ishizawa Keisuke、Tamaki Toshiaki、Ikeda Yasumasa 2020

[雑誌論文] Antibiotic prescriptions for Japanese outpatients with acute respiratory tract infections (2013-2015): A retrospective Observational Study

Koyama Toshihiro、Hagiya Hideharu、Teratani Yusuke、Tatebe Yasuhisa、Ohshima Ayako、Adachi Mayu、Funahashi Tomoko、Zamami Yoshito、Tanaka Hiroyoshi Y.、Tasaka Ken、Shinomiya Kazuaki、Kitamura Yoshihisa、Sendo Toshiaki、Hinotsu Shiro、Kano Mitsunobu R. 2020

[雑誌論文] Comparison of Hemorrhagic Risk between Prasugrel and Clopidogrel: a Retrospective Study using Adverse Drug Event Reporting Databases

Hagiwara Hiromi、Fukuta Hidekatsu、Niimura Takahiro、Zamami Yoshito、Ishizawa Keisuke、Kimura Kazunori、Kamiya Takeshi、Ohte Nobuyuki 2020

[雑誌論文] Investigation of drugs affecting hypertension in bevacizumab‐treated patients and examination of the impact on the therapeutic effect

Yagi Kenta、Mitstui Marin、Zamami Yoshito、Niimura Takahiro、Izawa‐Ishizawa Yuki、Goda Mitsuhiro、Chuma Masayuki、Fukunaga Kimiko、Shibata Takahiro、Ishida Shunsuke、Sakurada Takumi、Okada Naoto、Hamano Hirofumi、Horinouchi Yuya、Ikeda Yasumasa、Yanagawa Hiroaki、Ishizawa Keisuke 2020

[雑誌論文] Deletion of H-ferritin in macrophages alleviates obesity and diabetes induced by high-fat diet in mice

Ikeda Yasumasa、Watanabe Hiroaki、Shiuchi Tetsuya、Hamano Hirofumi、Horinouchi Yuya、Imanishi Masaki、Goda Mitsuhiro、Zamami Yoshito、Takechi Kenshi、Izawa-Ishizawa Yuki、Miyamoto Licht、Ishizawa Keisuke、Aihara Ken-ichi、Tsuchiya Koichiro、Tamaki Toshiaki 2020

[雑誌論文] Preventive Effects of Quercetin against the Onset of Atherosclerosis-Related Acute Aortic Syndromes in Mice

Kondo Masateru、Izawa-Ishizawa Yuki、Goda Mitsuhiro、Hosooka Mayuko、Kagimoto Yuu、Saito Naoko、Matsuoka Rie、Zamami Yoshito、Chuma Masayuki、Yagi Kenta、Takechi Kenshi、Tsuneyama Koichi、Ishizawa Keisuke 2020

[雑誌論文] Risk factors of immune checkpoint inhibitor-related interstitial lung disease in patients with lung cancer: a single-institution retrospective study

Okada Naoto、Matsuoka Rie、Sakurada Takumi、Goda Mitsuhiro、Chuma Masayuki、Yagi Kenta、Zamami Yoshito、Nishioka Yasuhiko、Ishizawa Keisuke 2020

[雑誌論文] Differences in risk factors for anticoagulant‐related nephropathy between warfarin and direct oral anticoagulants: Analysis of the Japanese adverse drug event report database

Mitsuboshi Satoru、Niimura Takahiro、Zamami Yoshito、Ishizawa Keisuke 2020

[雑誌論文] Concomitant Use of Acetaminophen and Aspirin Increases Risk of Kidney Injury: Analysis of the Japanese Adverse Drug Event Report Database

Mitsuboshi Satoru、Niimura Takahiro、Zamami Yoshito 2020

[雑誌論文] Association Between Immune-Related Adverse Events and Clinical Efficacy in Patients with Melanoma Treated With Nivolumab: A Multicenter Retrospective Study

Okada Naoto、Kawazoe Hitoshi、Takechi Kenshi、Matsudate Yoshihiro、Utsunomiya Ryo、Zamami Yoshito、Goda Mitsuhiro、Imanishi Masaki、Chuma Masayuki、Hidaka Noriaki、Sayama Koji、Kubo Yoshiaki、Tanaka Akihiro、Ishizawa Keisuke 2019

[雑誌論文] Factors Associated With Immune Checkpoint Inhibitor?Related Myocarditis

Zamami Yoshito、Niimura Takahiro、Okada Naoto、Koyama Toshihiro、Fukushima Keijo、Izawa-Ishizawa Yuki、Ishizawa Keisuke 2019

[学会発表] 医療ビッグデータ解析と基礎研究を融合した薬剤性副作用の機序解明および治療薬の開発

新村 貴博, 座間味 義人, 石澤 有紀, 合田 光寛, 武智 研志, 中馬 真幸, 福島 圭穣, 堀ノ内 裕也, 池田 康将, 藤野 裕道, 土屋 浩一郎, 石澤 啓介 2019

[雑誌論文] Nerve growth factor (NGF) has an anti-tumor effects through perivascular innervation of neovessels in HT1080 fibrosarcoma and HepG2 hepatitis tumor in nude mice

Kawasaki Hiromu、Goda Mitsuhiro、Fukuhara Satoko、Hashikawa-Hobara Narumi、Zamami Yoshito、Takatori Shingo 2019

[学会発表] Successful dose adjustment of vancomycin utilizing cystatin C in septic patients with bacterial meningitis: A case report

Masayuki Chuma, Masateru Kondo, Yoshito Zamami, Kenshi Takechi, Mitsuhiro Goda, Naoto Okada, Akitomo Shibata, Mizuho Asada, Jun Oto, Hiroaki Yanagawa, Keisuke Ishizawa 2019

[学会発表] 大規模医療情報データベースを活用したオキサリプラチン誘発末梢神経障害に対する予防薬探索

合田 光寛, 座間味 義人, 新村 貴博, 川尻 雄大, 武智 研志, 中馬 真幸, 萱野 純史, 濱野 裕章, 岡田 直人, 小林 大介, 島添 隆雄, 石澤 有紀, 桐野 靖, 中村 敏己, 寺岡 和彦, 石澤 啓介 2019

[学会発表] Development of therapeutic agents using drug discovery tools and large-scale medical information

Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Mitsuhiro Goda, Naoto Okada, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Keisuke Ishizawa 2019

[学会発表] 大規模医療情報データベースを活用した周術期領域における薬剤疫学研究

座間味 義人, 石澤 有紀, 新村 貴博, 小山 敏広, 濱野 裕章, 岡田 直人, 合田 光寛, 武智 研志, 中馬 真幸, 堀ノ内 裕也, 桐野 靖, 中村 敏己, 寺岡 和彦, 石澤 啓介 2019

[学会発表] Effect of new preventive medicine on cisplatin-induced acute kidney injury

Mitsuhiro Goda, Kazuhito Saike, Masaya Kanda, Takahiro Niimura, Kenshi Takechi, Masayuki Chuma, Yuki Izawa-Ishizawa, Yoshito Zamami, Keisuke Ishizawa 2019

[学会発表] ドラッグリポジショニング手法を用いたバンコマイシン関連腎障害の予防薬探索とその有用性の検討

中馬 真幸, 合田 光寛, 谷 友歩, 座間味 義人, 武智 研志, 石澤 有紀, 濱野 裕章, 石田 俊介, 新村 貴博, 近藤 正輝, 坂東 貴司, 岡田 直人, 福島 圭穣, 藤野 裕道, 土屋 浩一郎, 堀ノ内 裕也, 池田 康将, 楊河 宏章, 石澤 啓介 2019

[学会発表] Nicorandil improve prognosis of cardiac arrest patient: A large-scale medical information analysis

Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Keisuke Ishizawa 2019

[学会発表] 大規模医療情報を活用した多施設共同臨床研究の提案

座間味 義人, 新村 貴博, 川尻 雄大, 合田 光寛, 相澤 風花, 岡田 直人, 濱野 裕章, 武智 研志, 中馬 真幸, 石澤 有紀, 楊河 宏章, 石澤 啓介 2019

[学会発表] 持続的腎代替療法

中馬 真幸, 武智 研志, 座間味 義人, 合田 光寛, 岡田 直人, 近藤 正輝, 石澤 啓介, 楊河 宏章 2019

[学会発表] 免疫チェックポイント阻害薬の副作用発現及び治療効果に関連するバイオマーカーについて

岡田 直人, 座間味 義人, 武智 研志, 新村 貴博, 中馬 真幸, 合田 光寛, 石澤 啓介 2019

[雑誌論文] Iron accumulation causes impaired myogenesis correlated with MAPK signaling pathway inhibition by oxidative stress

Ikeda Yasumasa、Satoh Akiho、Horinouchi Yuya、Hamano Hirofumi、Watanabe Hiroaki、Imao Mizuki、Imanishi Masaki、Zamami Yoshito、Takechi Kenshi、Izawa‐Ishizawa Yuki、Miyamoto Licht、Hirayama Tasuku、Nagasawa Hideko、Ishizawa Keisuke、Aihara Ken‐Ichi、Tsuchiya Koichiro、Tamaki Toshiaki 2019

[雑誌論文] Place of death trends among patients with dementia in Japan: a population-based observational study

Koyama Toshihiro、Sasaki Misato、Hagiya Hideharu、Zamami Yoshito、Funahashi Tomoko、Ohshima Ayako、Tatebe Yasuhisa、Mikami Naoko、Shinomiya Kazuaki、Kitamura Yoshihisa、Sendo Toshiaki、Hinotsu Shiro、Kano Mitsunobu R. 2019

[雑誌論文] Association between rapid antigen detection tests and antibiotics for acute pharyngitis in Japan: A retrospective observational study

Teratani Yusuke、Hagiya Hideharu、Koyama Toshihiro、Ohshima Ayako、Zamami Yoshito、Tatebe Yasuhisa、Tasaka Ken、Shinomiya Kazuaki、Kitamura Yoshihisa、Sendo Toshiaki、Hinotsu Shiro、Kano Mitsunobu R. 2019

[雑誌論文] Fall-related mortality trends in older Japanese adults aged ?65 years: a nationwide observational study

Hagiya Hideharu、Koyama Toshihiro、Zamami Yoshito、Tatebe Yasuhisa、Funahashi Tomoko、Shinomiya Kazuaki、Kitamura Yoshihisa、Hinotsu Shiro、Sendo Toshiaki、Rakugi Hiromi、Kano Mitsunobu R 2019

[雑誌論文] Potential Usefulness of Early Potassium Supplementation for Preventing Severe Hypokalemia Induced by Liposomal Amphotericin B in Hematologic Patients: A Retrospective Study

Okada Naoto、Azuma Momoyo、Imanishi Masaki、Zamami Yoshito、Kirino Yasushi、Nakamura Toshimi、Teraoka Kazuhiko、Abe Masahiro、Ishizawa Keisuke 2018

[学会発表] 大規模医療情報データベースおよび遺伝子発現データベースを活用した薬剤性心筋炎に対する予防薬の探索

新村 貴博、座間味 義人、石澤 有紀、齊藤 広海、西牟田 剛広、今西 正樹、武智 研志、中馬 真幸、福島 圭穣、堀ノ内 裕也、池田 康将、藤野 裕道、土屋 浩一郎、石澤 啓介 2018

[雑誌論文] Relationship between the administration of nicardipine hydrochloride and the development of delirium in patients on mechanical ventilation.

Yoshito Zamami, Yuki Kouno, Takahiro Niimura, Masayuki Chuma, Toru Imai, Marin Mitsui, Toshihiro Koyama, Masahumi Kayano, Naoto Okada, Hirofumi Hamano, Mitsuhiro Goda, Masaki Imanishi, Kenshi Takechi, Yuya Horinouchi, Yutaka Kondo, Hiroaki Yanagawa, Yoshihisa Kitamura, Toshiaki Sendo, Yoshihito Ujike, Keisuke Ishizawa. 2018

[学会発表] 医療情報データベースを活用した抗がん剤誘発副作用に対する予防薬の探索研究

座間味 義人、新村 貴博、石澤 有紀、武智 研志、今西 正樹、中馬 真幸、堀ノ内 裕也、池田 康将、土屋 浩一郎、石澤 啓介 2018

[雑誌論文] Pharmacovigilance evaluation of the relationship between impaired glucose metabolism and BCR-ABL inhibitor use by using an adverse drug event reporting database

Okada Naoto、Niimura Takahiro、Zamami Yoshito、Hamano Hirofumi、Ishida Shunsuke、Goda Mitsuhiro、Takechi Kenshi、Chuma Masayuki、Imanishi Masaki、Ishizawa Keisuke 2018

[雑誌論文] Development and pharmacist-mediated use of tools for monitoring atypical antipsychotic-induced side effects related to blood glucose levels

Ishida Shunsuke、Takechi Kenshi、Bando Hiroshi、Imanishi Masaki、Zamami Yoshito、Chuma Masayuki、Yanagawa Hiroaki、Kirino Yasushi、Nakamura Toshimi、Teraoka Kazuhiko、Ishizawa Keisuke 2018

[学会発表] 救急・集中治療領域において大規模医療情報データベースを活用したトランスレーショナルリサーチ

座間味 義人、石澤 有紀、新村 貴博、今西 正樹、武智 研志、中馬 真幸、堀ノ内 裕也、池田 康将、桐野 靖、中村 敏己、寺岡 和彦、石澤 啓介 2018

[学会発表] ３段階の学年積み上げ式多職種連携教育

座間味義人、濱野 裕章、川原 里枝子、木内 恵里、合田 光寛、岡田 直人、柴田 高洋、今西 正樹、桐野 靖、中村 敏己、寺岡 和彦、吾妻 雅彦、石澤 啓介 2018

[学会発表] Drug repositioning for post cardiopulmonary resuscitation syndrome using large-scale medical claims

Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Kenshi Takechi, Masaki Imanishi, Masayuki Chuma, Yuya Horinouchi, Yasumasa Ikeda, Koichiro Tsuchiya, Keisuke Ishizawa 2018

[雑誌論文] Administration of Kampo medicine through a tube at an advanced critical care center

Niimura Takahiro、Zamami Yoshito、Imai Toru、Ito Tsuyoshi、Sagara Hidenori、Hiroyuki Hichiya、Esumi Satoru、Takechi Kenshi、Imanishi Masaki、Koyama Toshihiro、Amano Manabu、Kurata Naomi、Kitamura Yoshihisa、Nakura Hironori、Sendo Toshiaki、Ishizawa Keisuke 2018

[学会発表] Search for drugs that attenuate the antitumor effect of bevacizumab using adverse event database

Yoshito Zamami, Yuki Izawa-Ishizawa, Kenshi Takechi, Masaki Imanishi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Toshiaki Tamaki, Keisuke Ishizawa 2018

[雑誌論文] Trends in Polypharmacy in Japan: A Nationwide Retrospective Study

Onoue Hiroshi、Koyama Toshihiro、Zamami Yoshito、Hagiya Hideharu、Tatebe Yasuhisa、Mikami Naoko、Shinomiya Kazuaki、Kitamura Yoshihisa、Hinotsu Shiro、Sendo Toshiaki、Ouchi Yasuyoshi、Kano Mitsunobu R. 2018

[学会発表] 大規模医療情報データベースを活用した抗がん剤誘発副作用に対する予防薬の探索

座間味 義人、川尻 雄大、新村 貴博、合田 光寛、岡田 直人、濱野 裕章、武智 研志、中馬 真幸、堀ノ内 裕也、石澤 有紀、池田 康将、小林 大介、島添 隆雄、石澤 啓介 2018

[学会発表] 大規模医療情報および生命科学データベースを活用したトランスレーショナルリサーチ

座間味 義人 2018