トップ研究者を探すTS抑制ベクターによる5-FU系抗腫瘍剤増感療法

TS抑制ベクターによる5-FU系抗腫瘍剤増感療法

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18591438
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
外科学一般
研究機関 香川大学
代表研究者 上野 正樹
研究分担者 黄 政龍
研究分担者 石川 真也
研究分担者 横見瀬 裕保
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額(合計) 4,010,000 (直接経費 :3,500,000、間接経費 :510,000)
配分額(履歴) 2007年度:2,210,000 (直接経費 :1,700,000、間接経費 :510,000)
2006年度:1,800,000 (直接経費 :1,800,000)
キーワード 遺伝子治療
thymidylate synthase
5-FU
アデノウィルスベクター
RNA干渉
化学療法
gene therapy
thymidylate synthase
5-FU
adenoviral vector
RNA interference
chemotherapy

研究成果

[雑誌論文] Wntl overexpression associated with tumor proliferation and a poor prognosis in non-small cell lung cancer patients

Nakashima, T, Ueno, M, et. al. 2008

[雑誌論文] The expression of osteopontin is increased in vessels with blood-brain bather impairment

Iwanaga, Y, Ueno, M, et. al. 2008

[雑誌論文] Wnt1 overexpression associated with tumor proliferation and o poor prognosis in non-small cell lung cancer patients

Nakashima T, Ueno M, et. al. 2008

[雑誌論文] The expression of osteopontin is increased in vessels with blood-brain barrier impairment

Iwanaga Y, Ueno M, et. al. 2008

[雑誌論文] Wnt1 overexpression associated with tumor proliferation and a poor prognosis in non-small cell lung cancer patients

Nakashima T, Ueno M, et. al. 2008

[学会発表] Microarray analysis of BBB-damaged vessels extracted by microdissection

Ueno M, et. al. 2007

[雑誌論文] E2F1 overexpression correlates with thymidylate synthase and surviving gene expressions and tumor proliferation in non-small-cell lung cancer

Huang C, Ueno M, et. al. 2007

[雑誌論文] Overexpression of matrix metalloproteinase-7(MMP-7)correlates with tumor proliferation, and a poor prognosis in non-small cell lung cancer

Liu D, Ueno M, et. al. 2007

[雑誌論文] Overexpression of matrix metalloproteinase-7(MMP-7) correlates with tumor proliferation, and a poor prognosis in non-small cell lung cancer

Liu, D, Ueno, M, et. al. 2007

[雑誌論文] Overexpression of matrix metalloproteinase-7(MMP-7)correlates with tumor proliferation,and a poor prognosis in non-small cell lung cancer

Liu D, Ueno M, et. al. 2007

[雑誌論文] E2Fl overexpression correlates with thymidylate synthase and survivingene expressions and tumor proliferation in non-small-cell lung cancer

Huang C, Ueno M, et. al. 2007

[学会発表] Microarray analysis of BBB-damaged vessels extracted by microdissection

Ueno M, et. al. 2007

[雑誌論文] E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non- small cell lung cancer

Huang, C, Ueno, M, et. al. 2007

[学会発表] Microarray analysis of BBB-damaged vessels extracted by microdissection

Ueno, M, et. al. 2007

[学会発表] E2FI overexpression associated with TS and surviving gene expressionsin non-small cell lung cancer

Huang C, Liu D, et. al. 2007

[学会発表] E2F1 overexpression associated with TS and surviving Gene expressions in non-small cell lung cancer

Huang, C, Liu, D, et. al. 2007

[学会発表] E2F1 overexpression associated with TS and surviving gene expressions in non-small cell lung cancer

Huang C, Liu D, et. al. 2007

[雑誌論文] Two pathways of apoptosis are simultaneously induced in the embroyonal brains of neural cell-specific HIF-lalpha-deficient mice

Masaki Ueno, et al. 2006

[雑誌論文] Effects of aging and HIF-lalpha deficiency on permeability of hippocampal vessels

Masaki Ueno, et al. 2006

[雑誌論文] Tailor-made chemotherapy for non-small cell lung cancer patients

Cheng-long Huang, et al. 2006

[雑誌論文] MRP-1/CD9 gene transduction regulates the actin cytoskeleton through the downregulation of WAVE2

Cheng-long Huang, et al. 2006