トップ研究者を探す特発性血小板減少性紫斑病における自己反応性T細胞クローンの機能解析

特発性血小板減少性紫斑病における自己反応性T細胞クローンの機能解析

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18591069
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
内科系臨床医学
血液内科学
研究機関 愛媛大学
代表研究者 羽藤 高明
研究分担者 安川 正貴
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額(合計) 3,880,000 (直接経費 :3,400,000、間接経費 :480,000)
配分額(履歴) 2007年度:2,080,000 (直接経費 :1,600,000、間接経費 :480,000)
2006年度:1,800,000 (直接経費 :1,800,000)
キーワード 血小板
特発性血小板減少性紫斑病
インテグリン
GPIIb-IIIa
Talin
T細胞
platelet
idiopathic thrombocytopenic immure
mteerin
GPTTh-Tira
talin

研究成果

[雑誌論文] Cooperative role of the membrane-proximal and distal residues of the integrin ?3 cytoplasmic domain in regulation of talin-mediated fib? 3 activation

Hato, T, Yamanouchi, J, Tamura, T, Yakushijin, Y, Sakai, I, Yasukawa, M 2008

[雑誌論文] Cooperative role of the membrane-proximal and distal residues of the integrin?3 cytoplasmic domain in regulation of talin-mediated?IIb?3 activation

Hato T, et. al. 2008

[雑誌論文] Gooperative role of the membrane-proximal and distal residues of the integrin β3 cytoplasmic domain in regulation of talin-mediated αIIbβ3 activation

Hato T, et. al. 2008

[雑誌論文] Follicular dendritic cell tumor as unknown primary tumor

Yakushijin, Y, Shikata, H, Kito, K, Ohshima, K, Kojima, K, Hato, T, Hasegawa, H, Yasukawa, M 2007

[雑誌論文] Absence of chlamydial infection in Japanese patients with ocular adnexal lymphoma of mucosa-associated lymphoid tissue

Yakushijin, Y, Kodama, T, Takaoka, I, Tanimoto, K, Bessho, H, Sakai, I, Hato, T, Hasegawa, H, Yasukawa, M 2007

[雑誌論文] Budd-Chiari syndrome associated with hypereosinophilic syndrome ; A case report

Inoue, A, Michitaka, K, Shigematsu, S, Konishi, I, Hirooka, M, Hiasa, Y, Matsui, H, Matsuura, B, Horiike, N, Hato, T, Miyaoka, H, Onji, M 2007

[雑誌論文] Identification of critical residues for regulation of integrin activation in the 76-77 loop of the integrin ? 3 I-like domain

Hato, T, Yamanouchi, J, Yakushijin, Y, Sakai, I, Yasukawa, M 2006

[雑誌論文] Human herpesvirus 6 impairs differentiation of monocytes to dendritic cells

Niiya, H, Lei, J, Guo, Y, Azuma, T, Yakushijin, Y, Sakai, I, Hato, T, Tohyama, M, Hashimoto, K, Yasukawa, M 2006

[雑誌論文] Cappucino mutation in an autoimmune-prone strain of mice suggests a role of platelet function in the progression of immune complex crescentic elomerulonenhritis

Yoshida, M, Saiga, K, Hato, T, Iwaki, S, Niiya, T, Arita, N, Komori, H, Tsubaki, T, Furukawa, H, Terada, M, Maeyama, K, Nemoto, K, Nose, M, Ono, M 2006

[雑誌論文] Identification of critical residues for regulation of integrin activation in the β6-α7 loop of the integrin β3 I-like domain.

Hato T et al. 2006

[雑誌論文] Identification of critical residues for regulation of integrin activation in the ?6-?7 loop of the integrin ?3 I-like domain

Hato T, et. al. 2006