トップ研究者を探すゲノミクス・プロテオミクスによる環境化学物質の新しい健康影響指標の探索

ゲノミクス・プロテオミクスによる環境化学物質の新しい健康影響指標の探索

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18590559
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
社会医学
衛生学
研究機関 徳島大学
代表研究者 有澤 孝吉
研究分担者 六反 一仁
研究分担者 上村 浩一
研究分担者 日吉 峰麗
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額(合計) 3,710,000 (直接経費 :3,500,000、間接経費 :210,000)
配分額(履歴) 2007年度:910,000 (直接経費 :700,000、間接経費 :210,000)
2006年度:2,800,000 (直接経費 :2,800,000)
キーワード カドミウム曝露集団(ヒト)
ストレスチップ
クラスター解析
四塩化炭素
肝障害
プロテオーム解析
タンパク質相対定量
ビスフェノールA曝露マウス
Cd-exposed population
Stress chip
Cluster analysis
Carbon tetrachloride
Liver injury
Proteomic analysis
Relative quantification of proteins

研究成果

[学会発表] Associations of cadmium-induced low molecular weight proteinuria with cancer mortality and cancer incidence rate

Arisawa, K 2008

[雑誌論文] Circulating osteoprotegerin associates with age and systolic blood pressure but not with lipid profile or fasting glucose in postmenopausal women.

Uemura H, et. al. 2008

[雑誌論文] Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor KB ligand in postmenopausal women

Uemura, H 2008

[学会発表] Associations of environmental exposure to dioxins with hypertension, hyperlipidemia, thyroid disease and allergic coryza among general inhabitants in Japan

Uemura, H 2008

[雑誌論文] Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor κB ligand in postmenopausal women.

Uemura H, et. al. 2008

[学会発表] 日本の一般環境におけるダイオキシン曝露と高血圧、高脂血症、甲状腺疾患、アレルギー性鼻炎との有病状況との関係の検討

上村 浩一, 他 2008

[学会発表] Body burden of dioxins in generalinhabitants in Japan-An investigation of blood levels of dioxins

Uemura, H 2008

[雑誌論文] Circulating osteoprotegerin associates with age and systolic blood pressure but not with lipid profile or fasting glucose in postmenopausal women

Uemura, H 2008

[学会発表] 日本の一般環境におけるダイオキシン曝露と高血圧、高脂血症、甲状腺疾患、アレルギー性鼻炎との有病状況との関係の検討.

上村 浩一, 他. 2008

[雑誌論文] Cadmium-induced renal dysfunction and mortality in two cohorts : disappearance of the association in a generation born later

Arisawa, K 2007

[雑誌論文] Cause-specific mortality and cancer incidence rates in relation to urinary β2-microglobulin: 23-year follow-up study in a cadmium-polluted area.

Arisawa K, et. al. 2007

[学会発表] Dietary intake of dioxins among Japanese population estimated by duplicate portion analysis : low proportion of adults whose long-term intake exceeded the tolerable daily intake

Arisawa, K 2007

[雑誌論文] Cause-specific mortality and cancer incidence rates in relation to urinary 82-microglobulin : 23-year follow-up study in a cadmium-polluted area

Arisawa, K 2007

[学会発表] カドミウムによる低分子量蛋白尿とがん死亡率およびがん罹患率.

有澤 孝吉, 他. 2007

[学会発表] Dietary intake of dioxins among Japanese population estimated by duplicate portion analysis:low proportion of adults whose long-term intake exceeded the tolerable daily intake

Arisawa K, et. al. 2007

[雑誌論文] Cause-specific mortality and cancer incidence rates in relation to urinary β2-microglobulin:23-year follow-up study in a cadmium-polluted area

Arisawa K, et. al. 2007

[学会発表] Dietary intake of dioxins among Japanese population estimated by duplicate portion analysis: low proportion of adults whose long-term intakeexceeded the tolerable daily intake.

Arisawa K, et. al. 2007

[雑誌論文] Cadmium-induced renal dysfunction and mortality in two cohorts: disappearance of the association in a generation born later.

Arisawa K, et. al. 2007

[雑誌論文] Cadmium-induced renal dysfunction and mortality in two cohorts: disappearance of the association in a generation born later

Arisawa K, et. al. 2007

[学会発表] 日本の一般環境におけるダイオキシン類の人体への蓄積状況〜血液中のダイオキシン類濃度の検討〜.

上村 浩一, 他. 2007

[学会発表] Relationships between circulating osteoprotegerin and the risk factors of vascular disorders in postmenopausal women

Uemura, H 2007

[学会発表] Associations of low levels exposure to dioxins with prevalent diabetes in Japanese general population

Uemura H, et. al. 2007

[学会発表] Associations of low levels exposure to dioxins with prevalent diabetes in Japanese general population

Uemura, H 2007

[学会発表] Associations of low levels exposure to dioxins with prevalent diabetes in Japanese general population.

Uemura H, et. al. 2007

[雑誌論文] Human T-cell lymphotropic virus type-1 infection and risk of cancer : 15.4 year longitudinal study among atomic bomb survivors in Nagasaki,Japan.

Arisawa K, et al. 2006

[雑誌論文] ダイオキシンの健康リスクと食の安全.

有澤孝吉. 2006

[図書] 遺伝 別冊 食の安全科学 19

有澤 孝吉 2006

[雑誌論文] Human T-cell lymphotropic virus type-1 infection and risk of cancer : 15.4 year longitudinal study among atomic bomb survivors in Nagasaki, Japan

Arisawa, K 2006

[雑誌論文] Human T-cell lymphotropic virus type-1 infection and risk of cancer: 15.4 year longitudinal study among atomic bomb survivors in Nagasaki, Japan.

Arisawa K, et. al. 2006

[雑誌論文] Cadmium-induced renal dysfunction and mortality in two cohorts : disappearance of the association in a generation born later.

Arisawa K, et al.

[図書] 国際感染症と公衆衛生感染の疫学.

有澤 孝吉.

[雑誌論文] Circulating profiles of osteoprotegerin and soluble receptor activator of nuclear factor κB ligand in postmenopausal women.

Uemura H, et. al.