トップ›研究者を探す›自己免疫疾患における臓器特異性決定要因の解明

自己免疫疾患における臓器特異性決定要因の解明

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18590473
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
基礎医学
免疫学
研究機関 鶴見大学
徳島大学
代表研究者 黒田 範行
研究分担者 松本 満
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額（合計） 3,900,000 (直接経費 :3,600,000、間接経費 :300,000)
配分額（履歴） 2007年度：1,300,000 (直接経費 :1,000,000、間接経費 :300,000)
2006年度：2,600,000 (直接経費 :2,600,000)
キーワード 自己免疫疾患
糖尿病
NODマウス
AIRE
胸腺上皮細胞
臓器特異性
autoimmune
diabetes
NOD mouse

研究成果

[雑誌論文] Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology

Mitsuru Matsumoto, Yiqing Zhou, Shinji Matsuo, Hideki Nakanishi, Kenji Hirose, Hajimu Oura, Seiji Arase, Akemi Ishida-Yamamoto, Yoshimi Bando, Keisuke Izumi, Hiroshi Kiyonari, Naoko Oshima, Rika Nakayama, Akemi Matsushima, Fumiko Hirota, Yasuhiro Mouri, Noriyuki Kuroda, Shigetoshi Sano, and David D.Chaplin 2008

[雑誌論文] Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology

Mitsuru Matsumoto, Yiqing Zhou, Shinji Matsuo, Hideki Nakanishi, Kenji Hirose, Hajimu Oura, Seiji Arase, Akemi Ishida-Yamamoto, Yoshimi Bando, Keisuke Izumi, Hiroshi Kiyonari, Naoko Oshima, Rika Nakayama, Akemi Matsushima, Fumiko Hirota, Yasuhiro Mouri, Noriyuki Kuroda, Shigetoshi Sano, David D. Chaplin 2008

[雑誌論文] Essential Role of I_κB Kinase (IKK) α in Thymic Organogenesis Required for the Establishment of Self-Tolerance

Dan Kinoshita, Fumiko Hirota, Tsuneyasu Kaisho, Michiyuki Kasai, Keisuke Izumi, Yoshimi Bando, Yasuhiro Mouri, Akemi Matsushima, Shino Niki, Hongwei Han, Kiyotaka Oshikawa, Noriyuki Kuroda, Masahiko Maegawa, Minoru Irahara, Kiyoshi Takeda, Shizuo Akira, and Mitsuru Matsumoto 2006

[雑誌論文] Essential Role of I_k B Kinase(IKK) α in Thymic Organogenesis Required for the Establishment of Self-Tolerance

Dan Kinoshita, Fumiko Hirota, Tsuneyasu Kaisho, Michiyuki Kasai, Keisuke Izumi, Yoshimi Bando, Yasuhiro Mouri, Akemi Matsushima, Shino Niki, Hongwei Han, Kiyotaka Oshikawa, Noriyuki Kuroda, Masahiko Mae gawa, Minoru Irahara, Kiyosbi Takeda, Shizuo Akira, Mitsuru Matsumoto 2006

[雑誌論文] Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

Shino Niki, Kiyotaka Oshikawa, Yasuhiro Mouri, Fumiko Hirota, Akemi Matsushima, Masashi Yano, Hongwei Han, Yoshimi Bando, Keisuke Izumi, Masaki Matsumoto, Keiichi I. Nakayama, Noriyuki Kuroda, Mitsuru Matsumoto 2006

[雑誌論文] Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

Shino Niki, Kiyotaka Oshikawa, Yasuhiro Mouri, Fumiko Hirota, Akemi Matsushima, Masashi Yano, Hongwei Han, Yoshimi Bando, Keisuke Izumi, Masaki Matsumoto, Keiichi I.Nakayama, Noriyuki Kuroda, and Mitsuru Matsumoto 2006

[雑誌論文] Targeted deletion of the murine corneodesmosin gene delineates its essential role in skin and hair physiology

Mitsuru Matsumoto, Yiqing Zhou, Shinji Matsuo, Hideki Nakanishi, Kenji Hirose, Hajimu Oura, Seiji Arase, Akemi Ishida-Yamamoto, Yoshimi Bando, Keisuke Izumi, Hiroshi Kiyonari, Naoko Oshima, Rika Nakayama, Akemi Matsushima, Fumiko Hirota, Yasuhiro Mouri, Noriyuki Kuroda, Shigetoshi Sano, and David D.