トップ研究者を探すPEG化生理活性蛋白質の新規噴霧乾燥手法の構築

PEG化生理活性蛋白質の新規噴霧乾燥手法の構築

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18560722
研究種目 基盤研究(C)
研究分野 理工系
工学
プロセス工学
化工物性・移動操作・単位操作
研究機関 鳥取大学
代表研究者 古田 武
研究分担者 吉井 英文
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2008
研究ステータス 完了 (2008/4/1)
配分額(合計) 3,930,000 (直接経費 :3,600,000、間接経費 :330,000)
配分額(履歴) 2008年度:650,000 (直接経費 :500,000、間接経費 :150,000)
2007年度:780,000 (直接経費 :600,000、間接経費 :180,000)
2006年度:2,500,000 (直接経費 :2,500,000)
キーワード PEG 化カタラーゼ
噴霧乾燥酵素粉末
カタラーゼ
結晶化
マンニトール
PEG化カタラーゼ
アルコール脱水素酵素(ADH)
トレハロース
酵素残存活性
ウシ血清アルブミン(BSA)
ラクトグロブリン(Lg)

研究成果

[学会発表] 噴霧乾燥による酵素の粉末化

古田武, 山内浩資, H. JOREAU, 吉井英文 2009

[学会発表] マンニトールを基本賦形剤とした酵素粉末の作製

吉井英文, 山内浩資, H. JOREAU, 古田武 2009

[学会発表] Spray dryingof Saccharomyces cerevisiae K-9 containingS-Adenosyl-L-methionine

V. Lauruengtana1, H. Yoshii, T. Furuta, Y.Murakami, M. Kanai, H. Iefuji 2009

[学会発表] マンニトールを基本賦形剤とした酵素粉末の作製

吉井 英文 2009

[学会発表] Coagulation Inhibition of Soy Milk with Nigari by Soybean Water-soluble Polysaccharides

H. Yoshii, T-L. Neoh, T. Furuta and S. Inoue 2008

[雑誌論文] Kinetic study of thermally stimulateddissociation of inclusion complex of1-methylcyclopropene with α-cyclodextrinby thermal analysis

T. L. Neoh, K. Yamauchi, H. Yoshii and T.Furuta 2008

[学会発表] Influential Drying Conditions on Morphology of Spray-dried Powders ofM odel d-Limonene Emulsion

V. Paramita, K. Iida, T-L. Neoh, H. Yoshiiand T. Furuta 2008

[雑誌論文] 多孔性無水結晶糖質による亜麻油の包括粉末化

大橋哲也, 渋谷孝, 奥和之, 吉井英文, 古田武 2008

[学会発表] Influenceof protein-pectin multilayer interfacialmembranes on O/W emulsion

山内浩資, 吉井英文, 古田武 2008

[雑誌論文] Effects of protein on retention of ADH enzyme activity encapsulated in trehalose matrices by spray drying

H. Yoshii, at al. 2008

[学会発表] Coagulation Inhibition of Soy Milk with Nigari by Soybean Water-soluble Polysaccharides

H. Yoshii, et al. 2008

[雑誌論文] Encapsulation of protein by spray drying and crystal transformation method

H. Yoshii, at al. 2008

[雑誌論文] Effects of protein on retention of ADH enzyme activity encapsulated in trehalose matrices by spray drying

T. Furuta, H. Yoshii, et. al. 2008

[雑誌論文] Encapsulation of protein by spraydrying and crystal transformation method

H. Yoshii, T. L. Neoh, T. Furuta and M.Ohkawara 2008

[学会発表] Effect of Feed Liquid Temperature on theMorphology of Spray-dried Powder

V. Paramita, K. Iida, H. Yoshii and T. Furuta 2008

[雑誌論文] Effects of proteinon retention of ADH enzyme activity encapsulated in trehalose matrices by spraydrying,

H. Yoshii, F. Buche, N. Takeuchi, C. Terrol,M. Ohgawara, T. Furuta 2008

[雑誌論文] Visual observation of hydrolyzed potato starch granules by α-amylase with confocal laser scanning microscopy

T. Furuta, H. Yoshii, et. al. 2007

[学会発表] Encapsulation of proteins by spray drying and crystal transformation method

T. Furuta, H. Yoshii, et. al. 2007

[雑誌論文] Kinetics of Molecular encapsulation of 1-methylcyclopropene into α-cyclodextrin

T. Furuta, H. Yoshii, et. al. 2007

[学会発表] Encapsulation of proteins by spraydrying and crystal transformation method

H. Yoshii, T-L. Neoh, M. Ohkawara and T.Furuta 2007

[雑誌論文] Innovative crystal transformation ofdihydrate trehalose to anhydrous trehaloseusing ethanol

T. Ohashi, H. Yoshii, and T. Furuta 2007

[雑誌論文] Kinetics of Molecular encapsulationof 1-methylcyclopropene into α-cyclodextrin

T. L. Neoh, K. Yamauchi, H. Yoshii and T.Furuta 2007

[雑誌論文] Release kinetics of (-)-menthol from chewing gum

H. Yoshii, A. Sakane, D. Kawamura, T-L.Neoh, H. Kajiwara and T. Furuta 2007

[雑誌論文] Innovative crystal transformation of dihydrate trehalose to anhydrous trehalose using ethanol

T.Ohashi, H.Yoshii, T.Furuta 2007

[雑誌論文] Effect ofdrying methods on crystal transformation oftrehalose

T. Ohashi, H. Yoshii, T. Furuta 2007

[学会発表] Encapsulation of MCT oil in modified starches by spray drying233rd American Chemical Society National Meeting

H. Yoshii, M. Yasuda, H. Tobe, T-L. Neoh,and T. Furuta 2007

[学会発表] Visualization offlavor release in the spray-dried particle byconfocal laser scanning microscopy

H. Yoshii, D. Kawamura, T-L. Neoh, M. Ohkawara and T. Furuta, 2007

[雑誌論文] M. Ohkawara, P. Linko,Structural analysis of spray-dried powdersby confocal laser scanning microscopy

A. Soottitantawat, J. Peiney, Y. Uekaji, H.Yoshii, T. Furuta 2007

[雑誌論文] Visual observation of hydrolyzed potatostarch granules by α-amylase with confocallaser scanning microscopy

A. Soottitantawat, Y. Ikuta, H. Yoshii, T.Furuta, M. Paivi, F. Pirkko and P. Kaisa 2007

[雑誌論文] Encapsulation and release characteristics ofcarbon dioxide in α-cyclodextrin

T-L. Neoh, H. Yoshii and T. Furuta 2006

[学会発表] The releasing of encapsulated flavor from the spray dried powder

A.Soottitantawat1, T. Yamamoto, A. Endo, T.Ohmori, M. Nakaiwa, H. Yoshii and T.Furuta 2006

[学会発表] Effect of additives on the formation of hollow particles in spray-dried powders

H. Yoshii, A. Sootintantawatt, K. Iida, M.Ohgawara and T. Furuta 2006

[雑誌論文] Enzyme encapsulation with crystal transformation of anhydrous maltose or ahhydrous trehalose

H. Yoshii, T. Ohhashi, T. Furuta and P. Linko 2006

[雑誌論文] Effects of fortifying protein on conservation of ADH enzyme activity encapsulated in trehalose matrices by spray drying

Furuta T, Yoshii et al. 2006

[雑誌論文] Enzyme encapsulation with crystal transformation of anhydrous maltose or ahhydrous trehalose

H.Yoshii, T.Furuta, et al. 2006

[学会発表] アルコール脱水素酵素の噴霧乾燥法による作製

竹内奈緒美, 古田武, 吉井英文, 大橋哲也, 大川原正明 2006

[雑誌論文] Effect of protein on retention of ADH enzyme activity encapsulated in trehalose matrices by spray drying

Furuta T, Yoshii et al. 2006

[学会発表] Innovative crystal transformation of trehalose by the use of ethanol and the structure of the transformed anhydrous trehalose.

T. Ohashi, H. Yoshii and T. Furuta 2006

[学会発表] Effects of fortifying protein on conservation of ADH enzyme activity encapsulated in trehalose matrices by spray drying

H. Yoshii, F. Buche, N. Takeuchi, M.Ohgawara and T. Furuta 2006

[学会発表] Release kinetics of menthol from chewing gum

H. Yoshii, A. Sakane, D. Kawamura, T.L.Neoh, H. Kajiwara and T. Furuta 2006

[学会発表] Effect of protein on retention of ADH enzyme activity encapsulated in trehalose matrices by spray drying

H. Yoshii, F. Buche, N. Takeuchi, M.Ohgawara and T. Furuta 2006