トップ研究者を探すメタボリック症候群を予防する低グリセミック・インデックス食の分子基盤

メタボリック症候群を予防する低グリセミック・インデックス食の分子基盤

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-18300232
研究種目 基盤研究(B)
研究分野 総合・新領域系
総合領域
健康・スポーツ科学
応用健康科学
研究機関 徳島大学
代表研究者 武田 英二
研究分担者 山本 浩範
研究分担者 新井 英一
研究期間 開始年月日 2006/4/1
研究期間 終了年度 2008
研究ステータス 完了 (2008/4/1)
配分額(合計) 17,400,000 (直接経費 :15,600,000、間接経費 :1,800,000)
配分額(履歴) 2008年度:3,900,000 (直接経費 :3,000,000、間接経費 :900,000)
2007年度:3,900,000 (直接経費 :3,000,000、間接経費 :900,000)
2006年度:9,600,000 (直接経費 :9,600,000)
キーワード メタボリック症候群
グリセミック・インデックス
パラチノース
オレイン酸
リノール酸
キシリトール
遺伝子発現
組み合わせ食
めかぶ
大麦
デスアシルグレリン
白血球遺伝子
シュクロース
糖毒性
脂肪毒性
脂肪組織炎症性反応

研究成果

[雑誌論文] Does-dependent Effects of Barley Cooked with White Rice on postprandial Glucose and Desacyl Ghrelin Levels

Sakuma M, Yamanaka-Okumura H, Naniwa N, Matsumoto D, Tsunematsu M, Yamamoto H, Taketani Y, Takeda E 2009

[雑誌論文] Fermented ginseng improves the first-night effect in humans

Kitaoka K, Uchida K, Okamoto N, Chikahisa S, Miyazaki T, Takeda E, Hiroyoshi Sei H 2009

[雑誌論文] Improvement of glucose metabolism in patients with impaired glucose tolerance or diabetes by long-term administration of a palatinose-based liquid formula as a part of breakfast

Sakuma M, Arai H, Mizuno A, Fukaya M, Matsuura M, Sasaki H, Yamanaka-Okumura H, Yamamoto H, Taketani Y, Doi T, Takeda E 2009

[学会発表] Effects of long-term intake of xylitol on visceral fat accumulation in rats fed high-fat diet

Amo K, Arai H, Uebanso T, Fukaya M, Koganei M, Sasaki H, Yamamoto H, Taketani Y, Takeda E 2008

[雑誌論文] Palatinose and oleic acid act together to prevent pancreatic islet disruption in nondiabetic obese Zucker rats

Sato K, Arai H, Miyazawa Y, Fukaya M, Uebanso T, Koganei M, Sasaki H, Sato T, Yamamoto H, Taketani Y, Takeda E 2008

[図書] 食品技術総合事典・食品の機能性の評価手法 ・ヒト試験による機能性評価

武田英二, 奥村仙示 2008

[雑誌論文] Diurnal amplitudes of arterial pressure and heart rate are dampened in Clock mutant mice and adrenalectomized mice

Sei H, Oishi K, Chikahisa S, Kitaoka K, Takeda E, Ishida N 2008

[雑誌論文] Natto and viscous vegetables in a Japanese style meal suppress postprandial glucose and insulin responses

Taniguchi A, Yamanaka-Okumura H, Nishida Y, Yamamoto H, Taketani Y, Takeda E 2008

[雑誌論文] Extracts of Momordica charantia Suppress Postprandial Hyperglycemia in Rats

Uebanso T, Arai H, Taketani Y, Fukaya M, Yamamoto H, Mizuno A, Uryu K, Hada T, Takeda E 2007

[雑誌論文] Effects of palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men

Arai H, Mizuno A, Sakuma M, Fukaya M, Matsuo K, Muto K, Sasaki H, Matsuura M, Okumura H, Yamamoto H, Taketani Y, Doi T, Takeda E 2007

[図書] 機能性食品の事典

武田 英二 2007

[学会発表] Combination of food and nutrients for metabolic syndrome

Takeda E 2007

[雑誌論文] Dietary Palatinose and Oleic Acid Ameliorate Disorders of Glucose and Lipid Metabolism in Zucker Fatty Rats

Sato K, Arai H, Mizuno A, Fukaya M, Sato T, Koganei M, Sasaki H, Yamamoto H, Taketani Y, Doi T, Takeda E 2007

[雑誌論文] Phosphate Restriction in Diet Therapy, Nutrition and Kidney Disease

Takeda E, Yamamoto H, Nishida Y, Sato T, Sawada N, Taketani Y 2007

[雑誌論文] Mechanism of rapid-phase insulin response to elevation of portal glucose concentration

Fukaya M, Mizuno A, Arai H, Muto K, Uebanso T, Matsuo K, Yamamoto H, Taketani Y, Doi T, Takeda E 2007

[雑誌論文] Effects of a palatinose-based liquid diet (Inslow) on glycemic control and the second-meal effect in healthy men

Arai H, Mizuno A, Sakuma M, M Fukaya M, Matsuo K, Muto K, Sasaki H, Matsuura H, Okumura H, Yamamoto H, Taketani Y, Doi T, Takeda E 2007

[雑誌論文] Gene Expression in Low Glycemic IndexDiet-Impact on Metabolic Control, Tai ES, Gillies PJ (eds)

Takeda E, Arai H, Muto K, Matsuo K, Sakuma M, Fukaya M, Yamanaka-Okumura H, Yamamoto H, Taketani Y 2007

[図書] Nutrition and Kidney Diseases : A New Era, Contrib Nephrol. (Basel, Suzuki H, Kimmel PL (eds), Karger, vol 155)

Takeda Eiji 2007

[雑誌論文] The Anti-Obesity Effect of the Palatinose-Based Formula Inslow is Likely due to an Increase in the Hepatic PPAR α and Adipocyte PPAR γ・Gene Expressions

Matsuo K, Arai H, Muto K, Fukaya M, Sato T, Mizuno A, Sakuma M, Yamanaka-Okumura H, Sasaki H, Yamamoto H, Taketani Y, Doi T, Takeda E 2007

[図書] Nutrigenomics-Opportunities in Asia.Forum Nutr

Takeda E 2007

[雑誌論文] Early-phase insulin secretion is disturbed in obese subjects with glucose intolerance

Mizuno A, Arai H, Fukaya M, Sato M, Yamanaka-Okumura H, Takeda E, Doi T 2007

[雑誌論文] Nutrigenomics-Opportunities

Takeda E 2007

[雑誌論文] Water extract of Cordyceps sinensis(WECS)inhibits the RANKL-induced osteoclast differentiation

Mizuha Y, Yamamoto H, Sato T, Tsuji M, Masuda M, Uchida H, Sakai K, Taketani Y, Yasutomo K, Sasaki H, Takeda E 2007

[雑誌論文] Effect of late evening snack with rice ball on energy metabolism in liver cirrhosis

Yamanaka-Okumura H, Nakamura T, Takeuchi H, Miyake H, Katayama T, Arai H, Taketani Y, Fujii M, Shimada H, Takeda E 2006

[雑誌論文] A novel function of phosphate-mediated intracellular signal transduction pathways.

Takeda Eiji 2006

[雑誌論文] Immobilization decreases duodenal calcium absorption through a 1, 25-dihydroxyvitamin D-dependent pathway

Sato T, Yamamoto H, Sawada N, Nashiki K, Tsuji M, Nikawa T, Arai H, Morita K, Taketani Y, Takeda E 2006

[雑誌論文] Acute sffect of oral phosphate loading on serum fibroblast groeth factor 23 levels in healthy men

Nishida Y, Taketani Y, Yamanaka-Okumura H, Imamura F, Tanigichi A, Sato T, Shuto E, Nashiki K, Arai H, Yamamoto H, Takeda E 2006

[雑誌論文] Alternative promoters and renal cell-specific regulation of the mouse type IIa sodium-dependent phosphate contransporter gene

Yamamoto H, Tani Y, Kobayashi K, Taketani Y, Sato T, Arai H, Morita K, Miyamoto K, Pike JW, Kato S, Takeda E 2006

[雑誌論文] Acute effect of elevation of serum phosphorus on endothelial function with reference to oxidative stress and NO production

Shuto E, Taketani Y, Tanaka R, Harada N, Isshiki M, Sato M, Nashiki K, Amo K, Yamamoto H, Higashi Y, Nakaya Y, Takeda E

[図書] メタボリックシンドローム、栄養評価と治療

武田英二、阿望幾久子、上番増喬

抗不安抗うつ剤

GABA作動性ニューロン賦活剤

抗不安抗うつ剤

血中デスアシルグレリン濃度による血糖値・血中インスリン濃度の予測方法

血中デスアシルグレリン濃度による血糖値・血中インスリン濃度の予測方法