超好熱菌由来の高度耐熱性アルドラーゼの機能開発

トップ›研究者を探す›超好熱菌由来の高度耐熱性アルドラーゼの機能開発

代表研究者	櫻庭春彦
研究課題番号	KAKENHI-PROJECT-17613002
研究種目	基盤研究(C)
研究分野	極限環境生物学
研究機関	徳島大学
研究分担者	大島敏久
研究期間開始年月日	2005/4/1
研究期間終了年度	2007
研究ステータス	完了 (2007/4/1)
配分額（合計）	3,800,000 (直接経費 :3,500,000、間接経費 :300,000)
配分額（履歴）	2007年度：1,300,000 (直接経費 :1,000,000、間接経費 :300,000) 2006年度：1,000,000 (直接経費 :1,000,000) 2005年度：1,500,000 (直接経費 :1,500,000)
キーワード	酵素反応遺伝子バイオテクノロジー微生物酵素工学 X線結晶構造解析超好熱菌耐熱性酵素 DERA hyperthermophile Pyrobaculum aerophilum Thermotoga maritime archaea sequential aldol condensation acetaldehyde 2-deoxy-D-ribose-5-phosphate aldolase

研究成果

[雑誌論文] Structure of L-aspartate oxidase from the hyperthermophilic archaeon Sulfolobus tokodaii

Sakuraba, H., Yoneda, K., Asai, I., Tsuge, H., Katunuma, N., Ohshima, T 2008

[雑誌論文] Stfucture of L-aspartate oxidase from the hyperthermophilic archaeon Sulfolobus tokodaii.

Sakuraba, H., et. al. 2008

[雑誌論文] Structure of L-aspartate oxidase from the hyperthermophilicarchaeon Sulfolobus tokodaii

Sakuraba H., et. al. 2008

[雑誌論文] Gene expression and characterization of 2-keto-3-deoxygluconate kinase, a key enzyme in the modified Entner-Doudoroff pathway of the aerobic and acidphilic hyperthermophile Sulfolobus tokodaii.

Ohshima, T., et. al. 2007

[雑誌論文] Gene expression and characterization of 2-keto-3-deoxygluconate kinase, a key enzyme in the modified Entner-Doudoroff pathway of the aerobic and acidphilic hyperthermophile Sulfolobus tokodaii

Ohshima, T., Kawakami, R., Kanai, Y., Goda, S., Sakuraba, H 2007

[雑誌論文] Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-D-ribose-5-phosphate aldolase

Sakuraba, H., Yoneda, K., Yoshihara, K., Satoh, K., Kawakami, R., Uto, Y., Tsuge, H., Takahashi, K., Hori, H., Ohshima, T 2007

[図書] ポストノゲム時代のタンパク質研究

大島敏久, et al. 2007

[雑誌論文] Gene expression and characterization of 2-keto-3-deoxygluconate kinase,a key enzyme in the modified Entner-Doudoroff pathway of the aerobic and acidphilic hyperthermop hile Sulfolobus tokodaii.

Ohshima T., et. al. 2007

[雑誌論文] Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-D-ribose-5-phosphate aldolase

Sakuraba H., et. al. 2007

[学会発表] 超好熱菌由来アルドラーゼの結晶構造解析

櫻庭春彦 2007

[図書] 構造生物学-ポストゲノム時代のタンパク質研究-

櫻庭春彦,et. al. 2007

[雑誌論文] Sequential aldol condensation catalyzed by hyperthermophilic2-deoxy-D-ribose-5-phosphate aldolase.

Sakuraba, H., et. al. 2007

[雑誌論文] 超好熱菌タンパク質の耐熱化の分子戦略

櫻庭春彦, et. al. 2006

[雑誌論文] 超好熱菌タンパク質の耐熱化の分子戦略

櫻庭春彦, et al. 2006

[学会発表] Crystal structure of D-2-deoxyribose-5-phosphate aldolase from ahyperthermohilic archaeon Aeropyrum pernix

T. Ohshima 2005

[学会発表] Crystal structure of D-2-deoxyribose-5-phosphate aldolase from a hyperthermophilic archaeon Aeropyrum pernix

T. Ohshima, H. Sakuraba 2005

[雑誌論文] Crystal structure of the NAD biosynthetic enzyme quinolinate synthase

Sakuraba, H., Tsuge, H., Yoneda, K., Katunuma, N., Ohshima, T 2005

[雑誌論文] First archaeal inorganic polyphosphate/ATP-dependent NAD kinase, from hyperthermophilic archaeon Pyrococcus horikoshii : cloning, expression, and characterization

Sakuraba, H., Kawakami, R., Ohshima, T 2005

[雑誌論文] Crystal structure of the NAD biosynthetic enzyme quinolinate synthase

H.Sakuraba, et al. 2005

[雑誌論文] Crystal structure of the NAD biosynthetic enzyme quinolinate synthase

H. Sakuraba, et. al. 2005

[雑誌論文] 超好熱菌由来アルドラーゼのユニークな4次構造と高度耐熱性

櫻庭春彦, et al. 2005

[雑誌論文] First archaeal inorganic polyphosphate/ATP-dependent NAD kinase, from hyperthermophilic archaeon Pyrococcus horikoshii cloning, expression, and characterization

H.Sakuraba, et al. 2005

[雑誌論文] 超好熱菌由来アルドラーゼのユニークな4次構造と高度耐熱性

櫻庭春彦, et. al. 2005

[雑誌論文] First archaeal inorganic polyphosphate/ATP-dependent NAD kinase, from hyperthermophilic archaeon Pyrococcus horikoshii cloning, expression, and characterization

H. Sakuraba, et. al. 2005