トップ›研究者を探す›T細胞活性化の選択的制御によるアレルギー性結膜疾患の重症化の抑制

T細胞活性化の選択的制御によるアレルギー性結膜疾患の重症化の抑制

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17591838
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
外科系臨床医学
眼科学
研究機関 高知大学
代表研究者 福島 敦樹
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額（合計） 2,700,000 (直接経費 :2,700,000)
配分額（履歴） 2006年度：1,100,000 (直接経費 :1,100,000)
2005年度：1,600,000 (直接経費 :1,600,000)
キーワード アレルギー性結膜疾患
T細胞
共刺激分子
接着分子
4-1BB
OX40
VLA-4
VCAM-2
好酸球
PD-1
VCAM-1
シグナル伝達分子
サイトカイン
インターフェロンγ
TNFレセプター
Allergic Conjunctival Disease
T cell
Co-stimulatory Molecule
Adhesion Molecule
4-1BB
OX40
VLA-4
VCAM-2

研究成果

[雑誌論文] Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice.

Fukushima A et al. 2006

[雑誌論文] Roles of OX40 in the development of murine experimental allergic conjunctivitis : exacerbation and attenuation of eosniophil infiltration by stimulation and blocking of OX40.

Fukushima A et al. 2006

[雑誌論文] Role of VLA-4 in the development of allergic conjunctivitis in mice.

Fukushima A et al. 2006

[雑誌論文] Roles of OX40 in the development of murine experimental allergic conjunctivitis : exacerbation and attenuation of eosniophil infiltration by stimulation and blocking of OX40.

Fukushima A et al. 2006

[雑誌論文] Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice.

Fukushima A et al. 2006

[雑誌論文] Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.

Fukushima A et al. 2005

[雑誌論文] The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis.

Fukushima A et al. 2005

[雑誌論文] Dissection of antigen-specific humoral and cellular immune responses for he development of experimental immune-mediated blepharoconjunctivitis (EC) in C57BL/6 mice.

Fukushima A et al. 2005

[雑誌論文] Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.

Fukushima A et al. 2005

[雑誌論文] Fyn regulates eosinophil infiltration into the conjunctiva by downregulating the Th2 response.

Fukushima A et al. 2005

[雑誌論文] The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis.

Fukushima A et al. 2005

[雑誌論文] Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice.

Fukushima A et al. 2005

[雑誌論文] The immunization protocol determines whether endogenous interferon-γ suppresses the infiltration of eosinophils into the conjunctiva.

Fukushima A et al. 2005

[図書] 眼表面の免疫,眼科プラクティス 6眼科臨床に必要な解剖整理

福島 敦樹 2005

[雑誌論文] The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis.

Fukushima A et al. 2005