トップ研究者を探す原発性胆汁性肝硬変に対する免疫寛容誘導樹状細胞を用いた治療法の開発

原発性胆汁性肝硬変に対する免疫寛容誘導樹状細胞を用いた治療法の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17590651
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
内科系臨床医学
消化器内科学
研究機関 愛媛大学
代表研究者 AKBAR S・M・F
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額(合計) 3,400,000 (直接経費 :3,400,000)
配分額(履歴) 2006年度:1,200,000 (直接経費 :1,200,000)
2005年度:2,200,000 (直接経費 :2,200,000)
キーワード 原発性胆汁性肝硬変
制御性樹状細胞
Poly I:C
IL-10
自己抗体
Poly I : C
免疫治療
抗ミトコンドリア抗体
Primary biliary cirrhosis
Regulatory dendritic cells
Poly I : C
Interleukin-10
Bone marrow DC

研究成果

[雑誌論文] Dendritic cell-based therapy as a multidisciplinary approach to cancer treatment : present limitation and future scopes.

Akbar SM, Abe M, Yoshida M, Murakami H, Onji M 2006

[雑誌論文] Rationale for designing of antigen-specific immune therapy including dendritic cell-based therapy in patients with chronic hepatitis B virus infection.

Akbar SM, Murakami H, Horiike N, Onji M. 2006

[雑誌論文] Immune therapy including dendritic cell-based therapy in chronic hepatitis B virus infection.

Akbar SM, Horiike N, Onji M. 2006

[雑誌論文] Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice.

Niiya T, Akbar SM, et al. 2006

[雑誌論文] Rationale for designing of antigen-specific immune therapy including dendritic cell-based therapy in patients with chronic hepatitis B virus infection.

Akbar SM, Murakami H, Horiike N, Onji M 2006

[雑誌論文] impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice.

Niiya T, Akbar SM, et al. 2006

[雑誌論文] Rationale fcr desigdng of antigen-specific immune therapy including dendritic cell-based therapy in patients with chronic hepatitis B virus infection.

Akbar SM, Murakami H, Onji M. 2006

[雑誌論文] Immue therapy including dendritic cell-based therapy in chronic hepatitis B virus infection.

Akbar SM, Horiike N, Onji M 2006

[雑誌論文] Dendritic cell-based therapy as a multidisciplinary approach to cancer treatment : present limitation and future scopes.

Akbar SM, Abe M, Yoshida M, Murakami H, Onji M. 2006

[雑誌論文] Immune therapy including dendritic cell-baseed therapy in chronic hepatitis B virus infecticn.

Akbar SM, Horiike N, Onji M. 2006

[雑誌論文] Dendritic cell-based therapy as a multidisciplinary approach to cancer treatment : present limitaticn and future scopes.

Akbar SM, Abe M, Yoshida M, Murakami H, Onji M. 2006

[雑誌論文] Impaired functional capacities of liver dendritic cells from murine hepatitis B virus (HBV) carriers : relevance to low HBV-specific immune responses.

Hasebe A, Akbar SM, Furukawa S, Horiike N, Onji M. 2005

[雑誌論文] Therapeutic efficacy of decreased nitrite production by bezafibrate in patients with primary biliary cirrhosis.

Akbar SM, Furukawa S, Nakanishi S, Abe M, Horiike N, Onji M. 2005

[雑誌論文] Early development of primary biliary cirrhosis in female C57BL/6 mice because of poly IC administration.

Okada C, Akbar SM, Horiike N, Onji M. 2005

[雑誌論文] Impaired dendritic cell function resulting from chronic undernutrition disrupts the antigen-specific immune response in mice.

Niiya T, Akbar SM, Yoshida O, Miyake T, Matsuura B, Murakami H, Abe M, Hiasa Y, Onji M. 2001

[雑誌論文] Induction of anti-HBs in HB vaccine nonresponders in vivo by hepatitis B surface antigen-pulsed blood dendritic cells.

Akbar SM, Furukawa S, Yoshida, Hiasa Y, Horiike N, Onji M.

[雑誌論文] Induction of anti-HBs in HB vaccine nonresponders in vivo by hepatitis B surface antigen-pulsed blood dendritic cells.

Akbar SM, Furukawa S, Yoshida, Hiasa Y, Horiike N, Onji M