トップ›研究者を探す›抗原特異的CD8T細胞の活性化後誘導細胞死におけるインターロイキン-15の役割

抗原特異的CD8T細胞の活性化後誘導細胞死におけるインターロイキン-15の役割

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17590438
研究種目 基盤研究(C)
研究分野 生物系
医歯薬学
基礎医学
免疫学
研究機関 群馬大学
代表研究者 矢島 俊樹
研究分担者 吉開 泰信
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額（合計） 3,600,000 (直接経費 :3,600,000)
配分額（履歴） 2006年度：1,000,000 (直接経費 :1,000,000)
2005年度：2,600,000 (直接経費 :2,600,000)
キーワード 感染症
免疫学
細菌
Infectious disease
Immunology
Bacteria

研究成果

[雑誌論文] Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

Nakazato K, Yamada H, Yajima T, et al. 2007

[雑誌論文] Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

Nakazato K, Yamada H, Yajima T, Kagimoto Y, Kuwano H, Yoshikai Y. 2007

[雑誌論文] Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice.

Yoshihara K, Yajima T, Kubo C, Yoshikai Y. 2006

[雑誌論文] Toll-Like receptors 2 and 4 are differentially involved in Fas dependent apoptosis in Peyer's patch and the liver at an early stage after bile duct ligation in mice.

Ogawa A, Tagawa T, Nishimura H, Yajima T, Abe T, Arai T, Taniguchi M, Takeda K, Akira S, Nimura Y, Yosikai Y. 2006

[雑誌論文] IL-15 regulates CD8+ T cell contraction during primary infection

Yajima T, et al. 2006

[雑誌論文] Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice.

Yoshihara K, Yajima T, Kubo C, Yoshikai Y. 2006

[雑誌論文] Role of interleukin 15 in colitis induced by dextran sulphate sodium in mice

Yoshihara K, Yajima T, et al. 2006

[雑誌論文] Impaired protection against Mycobacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice.

Saito K, Yajima T, et al. 2006

[雑誌論文] Impaired protection against Mycobacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice.

Saito K, Yajima T, Kumabe S, Doi T, Yamada H, Sad S, Shen H, Yoshikai Y. 2006

[雑誌論文] Impaired protection against Mycobacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice

Saito K, Yajima T, Kumabe S, Doi T, Yamada H, Sad S, Shen H, Yoshikai Y. 2006

[雑誌論文] Impaired protection against Mycobacterium bovis bacillus Calmette-Guerin infection in IL-15-deficient mice.

Saito K, Yajima T, et al. 2006

[雑誌論文] A novel role of CD30/CD30L signaling in the generation of long-lived memory CD8^+T cell

Nishimura H, Yajima T, Muta H, Podack ER, Tani K, Yoshikai Y. 2005

[雑誌論文] A novel autoregulatory mechanism for transcriptional activation of the IL-15 gene by a nonsecretable isoform of IL-15 generated by alternative splicing.

Nishimura H, Fujimoto A, Tamura N, Yajima T, Wajjwaku W, Yoshikai Y. 2005

[雑誌論文] IL-15regulates CD8^+T cell contraction during primary infection

Yajima T., Yoshihara K., Nakazato K., Kumabe S., Koyasu S., Sad, S., Shen H., Kuwano H., Yoshikai Y. 2005

[雑誌論文] A novel role of IL-15 in early activation of memory CD8^+ CTL after reinfection.

Yajima T, Nishimura H, Sad S, Shen H, Kuwano H, Yoshikai Y. 2005

[雑誌論文] A novel role of CD30/CD30 ligand signaling in the generation of long-lived memory CD8^+T cells.

Nishimura H, Yajima T, Muta H, Podack ER, Tani K, Yoshikai Y. 2005

[雑誌論文] IL-15 regulates CD8^+T cell contraction during primary infection.

Yajima T, Yoshihara K, Nakazato K, Kumabe S, Koyasu S, Sad S, Shen H, Kuwano H, Yoshikai Y.