トップ›研究者を探す›D-アルギニンを基質として用いる環形動物のアルギニンキナーゼの構造と機能

D-アルギニンを基質として用いる環形動物のアルギニンキナーゼの構造と機能

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17570062
研究種目 基盤研究(C)
研究分野 生物系
生物学
基礎生物学
動物生理・行動
研究機関 高知大学
代表研究者 鈴木 知彦
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額（合計） 3,850,000 (直接経費 :3,700,000、間接経費 :150,000)
配分額（履歴） 2007年度：650,000 (直接経費 :500,000、間接経費 :150,000)
2006年度：800,000 (直接経費 :800,000)
2005年度：2,400,000 (直接経費 :2,400,000)
キーワード 酵素
基質特異性
D-アミノ酸
アルギニンキナーゼ
変異導入
フォスファゲンキナーゼ
グアニジノキナーゼ
クレアチンキナーゼ
enzyme
substrate snecificity
D-amino acid
arginine kinase
mutagenesis
phosnhaven kinase
guanidino kinase
creatine kinase

研究成果

[雑誌論文] Cytoplasmic and mitochondrial creatine kinases from the skeletal muscle of sperm whale(Physeter macrocephalus).Molecular cloning and enzyme characterization

Iwanami, K., Uda, K., Tada, H., and Suzuki, T. 2008

[雑誌論文] Cytoplasmic and mitochondrial creatine kinases from the skeletal muscle of sperm whale(Physeter macrocephalus). Molecular cloning and enzyme characterization

Iwanami, K., Uda, K., Tada, H., Suzuki, T 2008

[雑誌論文] Cooperativity in the Two-domain Arginine Kinase from the Sea Anemone Anthopleura japonicus. Int. J. Biol. Macromol

Tada, H., Nishimura, Y., and Suzuki, T. 2008

[雑誌論文] Cooperativity in the Two-domain Arginine Kinase from the Sea Anemone Anthopleura japonicus

Tada, H., Nishimura, Y., Suzuki, T 2008

[図書] Early Evolution of the Creatine Kinase Gene Family and the Capacity for Creatine Biosynthesis and Membrane Transport. In Creatine and Creatine Kinase in Health and Disease(Edited by Salomons, G. and Wyss, M.)pp.17-26

Ellington, W. R. and Suzuki, T. 2007

[学会発表] ケヤリアルギニンキナーゼの基質認識機構の解明

宇田 幸司・鈴木 知彦 2007

[学会発表] ヨロイイソギンチャク 2ドメイン型アルギニンキナーゼの酵素特性

多田 博, 鈴木 知彦 2007

[雑誌論文] Toxocara canis : Molecular cloning, characterization, expression and comparison of the kinetics of cDNA-derived arginine kinase

Wickramasinghe, S., Uda, K., Nagataki, M., Yatawara, L., Rajapakse, R. P. V., J., Watanabe, Y., Suzuki, T., Agatsuma, T 2007

[雑誌論文] A novel arginine kinase with substrate specificity toward D-arginine

Uda, K., and Suzuki, T. 2007

[雑誌論文] Evolution of Cytoplasmic and Mitochondrial Phosphagen Kinases Unique to Annelid Groups

Tanaka, K., Uda, K., Shimada, M., Takahashi, K., Gamou, S., Ellington, WR., and Suzuki, T. 2007

[雑誌論文] Origin of Creatine Kinase Isoforms : Insights from Basal Metazoans

Bertin, M., Pomponi, S., M., Kokufuta, C., Iwasaki, N., Suzuki, T., Ellington, W. R 2007

[学会発表] Enzymatic properties of Anthopleura 2-domain arginine kinase

Tada, H., Suzuki, T 2007

[雑誌論文] A novel arginine kinase with substrate specificity toward D-arginine

Uda, K., Suzuki, T 2007

[雑誌論文] Toxocara canis: Molecular cloning, characterization, expression and comparison of the kinetics of cDNA-derived arginine kinase

Wickramasinghe, S., Uda, K., Nagataki, M., Yatawara, L., Rajapakse, R.P.V.J., Watanabe, Y., Suzuki, T., and Agatsuma, T. 2007

[学会発表] Enzymatic properties of sea anemone 2-domain arginine kinase

Tada, H., Suzuki, T 2007

[雑誌論文] Arginine kinase from the beetle Cissites cephalotes(Olivier). Molecular cloning, phylogenetic analysis and enzymatic properties

Tanaka, K., Ichinari, S., Iwanami, K., Yoshimatsu, S., Suzuki, T 2007

[雑誌論文] Arginine kinase from the beetle Cissites cephalotes (Olivier).Molecular cloning, phylogenetic analysis and enzymatic properties

Tanaka, K., Ichinari, S, , Iwanami, K., Yoshimatsu, S., and Suzuki T. 2007

[雑誌論文] Arginine kinase from the beetle Cissites cephalotes (Olivier).Molecular cloning,phylogenetic analysis and enzymatic properties

Tanaka, K., Ichinari, S., Iwanami, K., Yoshimatsu, S., and Suzuki T. 2007

[雑誌論文] Evolution of Cytoplasmic and Mitochondrial Phosphagen Kinases Unique to Annelid Groups

Tanaka, K., Uda, K., Shimada, M., Takahashi, K., Gamou, S., Ellington, WR., Suzuki, T 2007

[図書] Early Evolution of the Creatine Kinase Gene Family and the Capacity for CreatineBiosynthesis and Membrane Transport.In Creatine and Creatine Kinase in Health and Disease (Edited by Salomons, G.and Wyss, M.)pp.17-26

Ellington, W.R.and Suzuki, T. 2007

[雑誌論文] Early Evolution of the Creatine Kinase Gene Family and the Capacity for Creatine Biosynthesis and Membrane Transport. In Creatine and Creatine Kinase in Health and Disease

Ellington, W. R., Suzuki, T 2007

[学会発表] Substrate recognition system of Sabellastarte arginine kinase

Uda, K., Suzuki, T 2007

[雑誌論文] Evolution of Cytoplasmic and Mitochondrial Phosphagen Kinases Unique to Annelid Groups

Tanaka, K., Uda, K., Shimada, M., Takahashi, K., Gamou, S., Ellington, WR., and Suzuki, T. 2007

[雑誌論文] Origin of Creatine Kinase Isoforms:Insights from Basal Metazoans.

Bertin, M., Pomponi, S.M., Kokufuta, C., Iwasaki, N., Suzuki, T. and Ellington, W.R. 2007

[学会発表] ヨロイイソギンチャク 2ドメイン型アルギニンキナーゼの酵素特性

多田 博・鈴木 知彦 2007

[学会発表] ケヤリアルギニンキナーゼの基質認識機構の解明

宇田 幸司・鈴木 知彦 2007

[学会発表] Reaction Mechanism of Arginine Kinase with Substrate Specificity Towards D-arginine.

Kouji Uda, Aiko Matsumoto, Tomohiko Suzuki 2006

[雑誌論文] クレアチンキナーゼの分子進化

鈴木, 知彦, 宇田, 幸司 2006

[雑誌論文] Evolution of the arginine kinase gene family.

Uda, K., Fujimoto, N., Akiyama, Y., Mizuta, K., Tanaka, K., Ellington, W.R., Suzuki, T. 2006

[雑誌論文] Evolution of the arginine kinase gene family

Uda, K., Fujimoto, N., Akiyama, Y., Mizuta, K., Tanaka, K., Ellington, W., R., Suzuki, T 2006

[学会発表] Substrate recognition system of phosphagen kinases. Importance of amino acid residue 95.

Kumiko Tanaka and Tomohiko Suzuki 2006

[学会発表] Substrate recognition system of mitochondorial taurocyamine kinase. Substrate inhibition caused by K95 to Y replacement.

KUMIKO TANAKA, TOMOHIKOSUZUKI 2006

[学会発表] Substrate recognition system of mitochondrial taurocyamine kinase. Substrate inhibition caused by K95 to Y replacement

Tanaka, K., Suzuki, T 2006

[雑誌論文] A novel arginine kinase with substrate specificity toward D-arginine.

Uda, K., Suzuki, T. 2006

[雑誌論文] Evolution of the arginine kinase gene family

Uda, K., Fujimoto, N., Akiyama, Y., Mizuta, K., Tanaka, K., Ellington, W.R., and Suzuki, T. 2006

[学会発表] A Novel Arginine Kinase with Substrate Specificity Towards D-arginine

KOUJI UDA, AIKO MATSUMOTO, TOMOHIKO SUZUKI 2006

[学会発表] Reaction mechanism of arginine kinase with substrate scecificity towards D-arginine

Uda, K., Matsumoto, I., Suzuki, T 2006

[図書] Evolution and divergence of creatine kinases. In Molecular Anatomy and Physiology of Proteins - Creatine Kinase (ed. C. Vial)

Ellington, W.R., Suzuki, T. 2006

[図書] Evolution and divergence of creatine kinases. In molecular Anatomy and Physiology of Proteins - Creatine Kinase (ed. C. Vial).New York: NovaScience pp.1-26. ISBN: 1-59454-715-7

Ellington, W. R. and Suzuki, T. 2006

[雑誌論文] Comparison of kinetic constants of creatine kinase isoforms

Matsushima, K., Uda, K., Ishida, K., Kokufuta, C., Iwasaki, N., Suzuki, T 2006

[学会発表] A Novel Arginine Kinase with Substrate Specificity Towards D-arginine

Uda,K., Matsumoto, A., Suzuki, T 2006

[雑誌論文] Comparison of kinetic constants of creatine kinase isoforms.

Matsushima, K., Uda, K., Ishida, K., Kokufuta, C., Iwasaki, N., Suzuki, T. 2006

[学会発表] Substrate recognition system of phosphagen kinases. Importance of amino acid residue 95

Tanaka, K., Suzuki, T 2006

[雑誌論文] クレアチンキナーゼの分子進化

鈴木 知彦, 宇田 幸司 2006

[雑誌論文] Comparison of kinetic constants of creatine kinase isoforms

Matsushima, K., Uda, K., Ishida, K., Kokufuta, C., Iwasaki, N. and Suzuki, T. 2006

[雑誌論文] Phosphagen kinase of the giant tubeworm Riftia pachyptila.Cloning and expression of cytoplasmic and mitochondrial isoforms of taurocyamine kinase

Uda, K., Tanaka, K., Bailly, X., Zal, F. and Suzuki, T. 2005

[雑誌論文] Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase.

Uda, K., Saishoji, N., Ichinari, S., Ellington, W.R., Suzuki, T. 2005

[雑誌論文] Hypotaurocyamine kinase evolved from a gene for arginine kinase

Uda, K., Iwai, A. and Suzuki, T. 2005

[学会発表] D-arginine concentrated in the marine worm Sabellastarte indica, and arginine kinase with substrate specificity for D-arginine

Uda, K., Suzuki, T 2005

[学会発表] Enzymatic properties of Sabellastarte arginine kinase with substrate specificity for D-arginine

Uda, K., Matsumoto, I., Shima, M., Suzuki, T 2005

[雑誌論文] Phosphagen kinase of the giant tubeworm Riftia pachyptila. Cloning and expression of cytoplasmic and mitochondrial isoforms of taurocyamine kinase.

Uda, K., Tanaka, K., Bailly, X., Zal, F.Suzuki, T. 2005

[学会発表] D-アミノ酸を基質とするケヤリ・アルギニンキナーゼの酵素機能解析

宇田 幸司・松本 愛子・島 めぐみ・鈴木 知彦 2005

[学会発表] ケヤリにおけるD-アルギニンの濃縮とD-アルギニンに活性をもつアルギニンキナーゼ

宇田 幸司・鈴木 知彦 2005

[雑誌論文] Hypotaurocyamine kinase evolved from a gene for arginine kinase.

Uda, K., Iwai, A., Suzuki, T. 2005

[雑誌論文] Hypotaurocyamine kinase evolved from a gene for arginine kinase

Uda, K., Iwai, A., Suzuki, T 2005

[学会発表] cDNA-derived amino acid sequence of arginine kinase from Cissites cephalotes

Ichinari, S., Iwanami, K., Uda, K., Suzuki, T., Yoshimatsu, S 2005

[雑誌論文] Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase

Uda, K., Saishoji, N., Ichinari, S., Ellington, W.R., and Suzuki, T. 2005

[学会発表] ヒラズゲンセイのアルギニンキナーゼの cDNA配列解析

市成 秀一・岩波 健太郎・宇田 幸司・鈴木 知彦・吉松 靖峯 2005

[雑誌論文] Phosphagen kinase of the giant tubeworm Riftia pachyptila. Cloning and expression of cytoplasmic and mitochondrial isoforms of taurocyamine kinase

Uda, K., Tanaka, K., Bailly, X., Zal, F., Suzuki, T 2005

[雑誌論文] Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase

Uda, K., Saishoji, N., Ichinari, S., Ellington, W., R., Suzuki, T 2005

[雑誌論文] Evolution and divergence of creatine kinases

Ellington, W. R., Suzuki, T