トップ研究者を探すES細胞を用いた悪性脳腫瘍に対する遺伝子・細胞治療の研究

ES細胞を用いた悪性脳腫瘍に対する遺伝子・細胞治療の研究

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17390402
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
外科系臨床医学
脳神経外科学
研究機関 香川大学
代表研究者 田宮 隆
研究分担者 長尾 省吾
研究分担者 河合 信行
研究分担者 三宅 啓介
研究分担者 香川 昌弘
研究分担者 松本 義人
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2007
研究ステータス 完了 (2007/4/1)
配分額(合計) 14,340,000 (直接経費 :13,200,000、間接経費 :1,140,000)
配分額(履歴) 2007年度:4,940,000 (直接経費 :3,800,000、間接経費 :1,140,000)
2006年度:3,800,000 (直接経費 :3,800,000)
2005年度:5,600,000 (直接経費 :5,600,000)
キーワード embryonic cell
neural stem cell
glioma
gene therapy
transplantation
YKL-40
embryonic stem cell
embryonic cell
neural stem cell
glioma
gene therapy
transplantation
YKL-40

研究成果

[雑誌論文] Targeting optimal biopsy location in basal ganglia germinoma using(11)C-methionine positron emission tomography

Kawai N, Miyake K, Nishiyama Y, Yamamoto Y, Miki A, Haba R, Imai T, Tamiya T, Nagao S 2008

[雑誌論文] Targeting optimal biopsy location in basal ganglia germinoma using(11)C-methionine positron emission tomography

Kawai N, Miyake K, Nishiyama Y, Yamamoto Y, Miki A, Haba R, Imai T, Tamiya T, Nagao S. 2008

[雑誌論文] Targeting optimal biopsy location in basal ganglia germinoma using(11)C-methionine positron emission tomography

Kawai, N., Miyake, K., Nishiyama, Y., Yamamoto, Y., Miki, A., Haba, R., Imai, T., Tamiya, T., Nagao, S 2008

[雑誌論文] Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage

Nakamura T, Kuroda Y, Yamashita S, Zhang X, Miyamoto O, Tamiya T, Nagao S, Xi G, Keep RF, Itano T. 2007

[雑誌論文] Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage

Nakamura T, Kuroda Y, Yamashita S, Zhang X, Miyamoto O, Tamiya T, Nagao S, Xi G, Keep RF, Itano T 2007

[学会発表] ERK1/2 involves in interferon-alpha induced inhibition of human astrocytoma U87 cells growth by down-regulating YKL-40 expression

Zhang, W., Nishiyama, A., Nagao, S., Zhang, X., Tamiya, T 2007

[学会発表] ERK1/2 involves in interferon-alpha induced inhibition of human astrocytoma U87 cells growth by down-regulating YKL-40 expression

Zhang W, Nishiyama A, Nagao S, Zhang X, Tamiya T 2007

[雑誌論文] Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage

Nakamura, T., Kuroda, Y., Yamashita, S., Zhang, X., Miyamoto, 0., Tamiya, T., Nagao, S., Xi, G., Keep, RF., Itano, T 2007

[雑誌論文] Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease

Wang, Q., Matsumoto, Y., Shindo, T., Miyake, K., Shindo, A., Kawanishi, M., Kawai, N., Tamiya, T., Nagao, S 2006

[雑誌論文] FDG-PET findings of the brain in lymphomatoid granulomatosis

Kawai, N., Miyake, K., Nishiyama, Y., Yamamoto, Y., Sasakawa, Y., Haba, R., Kushida, Y., Tamiya, T., Nagao, S 2006

[雑誌論文] Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury

Shindo T, Matsumoto Y, Wang Q, Kawai N, Tamiya T, Nagao S 2006

[雑誌論文] Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury

Shindo, T. Matsumoto, Y. Wang, Q. Kawai, N. Tamiya, T. Nagao, S 2006

[学会発表] Expression of ABC-transporter proteins in the human malignant gliomas

Miyake K, Matsumoto T, Tamiya T, Nagao S 2006

[雑誌論文] Differences in the neuronal stem cells survival, neuronal differentiation and neurological improvement after transplantation of neural stem cells between mild and severe experimental traumatic brain injury

Shindo T, Matsumoto Y, Wang Q, Kawai N, Tamiya T, Nagao S 2006

[学会発表] Transcranial epidural approach for giant pituitary adenomas invading the cavemous sinus and parasellar regions

Tamiya, T., Sindo, T., Sindo, A., Miyake, K., Kawanishi, M., Kagawa, M., Kawai, N., Nagao, S 2006

[雑誌論文] Iron metabolism after intracerebral hemorrhage in rat brain : role of transferrin

Nakamura T, Kuroda Y, Miyamoto O, Kawai N, Xi G, Keep RF, Tamiya T, Itano T, Nagao S 2006

[雑誌論文] FDG-PET findings of the brain in lymphomatoid granulomatosis

Kawai N, Miyake K, Nishiyama Y, Yamamoto Y, Sasakawa Y, Haba R, Kushida Y, Tamiya T, Nagao S 2006

[雑誌論文] Successful chemotherapy for congenital malignant gliomas: A report of two cases

Tamiya T, Takao S, Ichikawa T, Chayama K, Date I 2006

[学会発表] Transcranial epidural approach for giant pituitary adenomas invading the cavernous sinus and parasellar regions

Tamiya T, Sindo T, Sindo A, Miyake K, Kawanishi M, Kagawa M, Kawai N, Nagao S 2006

[雑誌論文] Successful chemotherapy for congenital malignant gliomas : A report of two cases

Tamiya, T., Takao, S., Ichikawa, T., Chayama, K., Date, I 2006

[雑誌論文] Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease

Wang Q, Matsumoto Y, Shindo T, Miyake K, Shindo A, Kawanishi M, Kawai N, Tamiya T, Nagao S 2006

[雑誌論文] 髄膜腫周囲脳浮腫の発生

田宮 隆, 小野恭裕, 大塚真司, 長尾省吾 2006

[雑誌論文] Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease

Wang Q, Matsumoto, Y, Shindo T, Tamiya T, et al. 2006

[雑誌論文] Successful chemotherapy for congenital malignant gliomas : A report of two cases

Tamiya T, Takao S, Ichikawa T, Chayama K, Date I 2006

[雑誌論文] Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells

Michiue H, Tomizawa K, Matsushita M, Tamiya T, et al. 2005

[雑誌論文] Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells

Michiue, H. Tomizawa, K. Matsushita, M. Tamiya, T. Lu, YF. Ichikawa, T. Date, I. Matsui, H 2005

[雑誌論文] Ubiquitination-resistant p53 protein transduction therapy facilitates anti-cancer effect on the growth of human malignant glioma cells

Michiue H, Tomizawa K, Matsushita M, Tamiya T, Lu YF, Ichikawa T, Date I, Matsui H 2005