トップ研究者を探す血管壁不安定化の分子機構の解明と治療戦略の開発

血管壁不安定化の分子機構の解明と治療戦略の開発

KAKEN 科学研究費助成事業データベース で見る
研究課題番号 KAKENHI-PROJECT-17390227
研究種目 基盤研究(B)
研究分野 生物系
医歯薬学
内科系臨床医学
循環器内科学
研究機関 東京大学
代表研究者 佐田 政隆
研究分担者 平田 恭信
研究分担者 石坂 信和
研究期間 開始年月日 2005/4/1
研究期間 終了年度 2006
研究ステータス 完了 (2006/4/1)
配分額(合計) 15,500,000 (直接経費 :15,500,000)
配分額(履歴) 2006年度:5,200,000 (直接経費 :5,200,000)
2005年度:10,300,000 (直接経費 :10,300,000)
キーワード 心筋梗塞
外膜
動脈硬化
血管
組織
内皮細胞
血管新生
炎症
粥腫
プラーク
急性冠症候群
アンジオテンシン
前駆細胞
Myocardial Infarction
Adventitia
Atherosclerosis
Blood Vessel
Tissue
Endothelial Cell
Angiogenesis
Inflammation

研究成果

[雑誌論文] Mobilization of CD34-Positive bone marrow-derived cells after coronary stent implantation : impact on restenosis.

Inoue, T., Sata, M., Hikichi, Y., Sohma, R., Fukuda, D., Uchida, T., Shimizu, M., Komoda, H., Node, K. 2007

[雑誌論文] CXCR4, a key modulator of vascular progenitor cells.

Sainz, J., Sata, M. 2007

[雑誌論文] Mobilization of CD34-Positive bone marrow-derived cells after coronary stent implantation : impact on restenosis.

Inoue, T., Sata, M., Hikichi, Y., Sohma, R., Fukuda, D., Uchida, T., Shimizu, M., Komoda, H., Node, K. 2007

[雑誌論文] CXCR4, a key modulator of vascular progenitor cells.

Sainz, J., Sata M. 2007

[雑誌論文] Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Sahara, M., Sata, M., Morita, T., Nakamura, K., Hirata, Y., Nagai, R. 2007

[雑誌論文] Role of Bone Marrow Cells in the pathogenesis of atherosclerosis

Sata, M. 2007

[雑誌論文] Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis.

Sumi, M., Sata, M., Toya, N., Yanaga, K., Ohki, T., Nagai, R. 2007

[雑誌論文] Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced anaiogenesis.

Sumi, M., Sata, M., Toya, N., Yanaga, K., Ohki, T., Nagai, R. 2007

[雑誌論文] Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Sahara, M., Sata, M., Morita, T., Nakamura, K., Hirata, Y., Nagai, R. 2007

[雑誌論文] Diverse contribution of bone marrow-derived cells to vascular-remodeling associated with pulmonary arterial hypertension and arterial neointimal formation.

Sahara, M., Sata, M., Morita, T., Nakamura, K., Hirata, Y., Nagai 2007

[雑誌論文] The role of circulating vascular progenitors in angiogenesis, vascular healing and pulmonary hypertension : Lessons from animal models.

Sata, M. 2006

[雑誌論文] The role of circulating vascular progenitors in angiogenesis, vascular healing and pulmonary hypertension : Lessons from animal models.

Sata, M 2006

[雑誌論文] Maintenance of Vascular Homeostasis by Bone Marrow-derived Cells.

Sainz, J., Sata, M. 2006

[図書] (分担執筆)2章病態骨髄由来細胞の役割慢性冠動脈疾患の臨床

佐田政隆, (小川久雄編集) 2006

[雑誌論文] The role of circulating vascular progenitors in angiogenesis, vascular healing and pulmonary hypertension : Lessons from animal models.

Sata, M. 2006

[雑誌論文] Maintenance of Vascular Homeostasis by Bone Marrow-derived Cells.

Sainz, J., Sata, M. 2006

[図書] (分担執筆) 2章病態骨髄由来細胞の役割 慢性冠動脈疾患の臨床

佐田政隆 (小川久雄編集) 2006

[雑誌論文] Circulating Osteoblast-Lineage Cells.

Sata, M., Tanaka, K., Nagai, R. 2005

[雑誌論文] Age-associated Aortic Stenosis in ApoE-deficient Mice.

Tanaka, K., Sata.M., ら 2005

[図書] Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches

Sata, M, Nagai, R 2005

[雑誌論文] Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury.

Sahara, M., Sata, M.ら 2005

[雑誌論文] Potent inhibitory effect of sirolimus on circulating vascular progenitor cells

Fukuda, D., Sata, M., ら 2005

[雑誌論文] The role of circulating precursors in vascular repair and lesion formation.

Sata, M., ら 2005

[雑誌論文] Human umbilical cord blood cells improve cardiac function after myocardial infarction.

Hirata, Y., Sata, M., ら 2005

[雑誌論文] The angiotensin II type 1 receptor blocker valsartan attenuates graft vasculopathy.

Yamamoto, T., Sata, M., ら 2005